Zobrazeno 1 - 10
of 31
pro vyhledávání: '"C. L. Eaton"'
Autor:
Sabapathy P. Balasubramanian, MW Reed, F.C. Hamdy, James W.F. Catto, C L Eaton, A Mitchell, Steve J. Winder, Simon S. Cross, J M Lippitt, F Hollingsbury
Publikováno v:
Histopathology. 53:561-566
AIMS Dystroglycan is an important structural and signalling protein that is expressed in most human cells. alpha-Dystroglycan has been investigated and found to be reduced in human cancers, but there is only one published study on the expression of b
Publikováno v:
The Prostate. 31:29-36
BACKGROUND. Polyunsaturated fatty acids (n-6) are reported to selectively kill malignant cells. Most investigations, however, did not compare neoplastic with non-neoplastic cells from the same tissue type. Here we evaluate the effects of n-6 fatty ac
Autor:
Keith Griffiths, Julia Margaret Wendy Gee, Carol Mary Dutkowski, C. L. Eaton, Denise Barrow, Helen E. Jones
Publikováno v:
The Prostate. 30:219-231
BACKGROUND The role of growth factors in prostate cell growth has been investigated as these peptides may be involved in the autonomous growth of hormone-independent prostate cancer. METHODS Responses of neoplastic (PC-3 and CPA) and non-neoplastic (
Publikováno v:
The Prostate. 25:210-218
The expression of transforming growth factor beta 1 (TGF-β1) in prostate specimens obtained from patients with benign prostatic hyperplasia (BPH, n = 32) and prostate carcinoma (n = 66) was investigated using Northern blot analysis and immunohistoch
Autor:
K J Reeves, G. van der Pluijm, C L Eaton, Freddie C. Hamdy, Nicola J. Brown, Marco G. Cecchini
Publikováno v:
The FASEB Journal. 23
Autor:
Ishtiaq Rehman, Stéphane Larré, Caroline A. Evans, James W.F. Catto, C L Eaton, Freddie C. Hamdy, Adam Glen, Phillip C. Wright
Publikováno v:
Proteomics. Clinical applications. 3(2)
Prostate cancer (PCa) is the most common cancer diagnosis and the second most common cause of cancer-related deaths in men. Currently, serum prostate-specific antigen (PSA) is the only biomarker widely used in the diagnosis and management of patients
Autor:
Freddie C. Hamdy, C.S. Gan, Simon S. Cross, James W.F. Catto, Phillip C. Wright, Adam Glen, C L Eaton, Ishtiaq Rehman
Publikováno v:
Journal of proteome research. 7(3)
The unpredictable behavior of prostate cancer presents a major clinical challenge during patient management. In order to gain an insight into the molecular mechanisms associated with prostate cancer progression, we employed the shot-gun proteomic app
Publikováno v:
The Prostate. 48(4)
In this study, defined culture conditions were used to examine the effects of recombinant TGFbeta1 on prostatic stromal cells and to determine the role of endogenous TGFbeta produced by these cells.Cells were grown +/- recombinant TGFbeta1 and cell p
Publikováno v:
The Prostate. 41(2)
The majority of the overgrowth in benign prostatic hyperplasia (BPH) specimens is comprised of connective tissue. Factors that control stromal growth in the prostate are poorly understood; however, members of the transforming growth factor beta (TGFb
Publikováno v:
The Prostate. 31(1)
Polyunsaturated fatty acids (n-6) are reported to selectively kill malignant cells. Most investigations, however, did not compare neoplastic with non-neoplastic cells from the same tissue type. Here we evaluate the effects of n-6 fatty acids on a non