Zobrazeno 1 - 10
of 33
pro vyhledávání: '"C. L. Cooney"'
Publikováno v:
Biotechnology and Bioengineering. 67:691-703
Autor:
C. L. Cooney, R. L. Dabora
Publikováno v:
Applied Molecular Genetics ISBN: 354052794X
This article focusses on lytic enzyme systems available in E. coli and their potential use for cellular disruption. In the systems described here the genetic information for lysis would be carried within the microbial host, either integrated or natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2b9e28a5f0d8eacace6adea7c492b55
https://doi.org/10.1007/bfb0009077
https://doi.org/10.1007/bfb0009077
Autor:
T, Schluep, C L, Cooney
Publikováno v:
Bioseparation. 7(6)
Triplex affinity interaction provides a new process for the purification of plasmid DNA, which is especially suited to meet the demands of a gene therapy use. We developed a method for the functionalization of a large pore affinity support suitable f
Publikováno v:
Biotechnology and bioengineering. 63(5)
The development of a safe and efficient bioreactor design has remained a challenge for the clinical application of immobilized enzymes. Specifically, the use of immobilized heparinase I has been the target of many studies to make heparin anticoagulat
Publikováno v:
The Journal of biological chemistry. 271(6)
In this study we have identified the primary heparin binding site of heparinase I (EC 4.2.2.7). Chemical and proteolytic digests of heparinase I were used in direct binding and competition assays, to map the regions of heparinase I that interact spec
Gene therapy: biotech's n + 1 technology. What they are teaching at MIT's Sloan School of Management
Autor:
N M, Summers, C L, Cooney
Publikováno v:
Bio/technology (Nature Publishing Company). 12(1)
Autor:
R L, Dabora, C L, Cooney
Publikováno v:
Advances in biochemical engineering/biotechnology. 43
This article focusses on lytic enzyme systems available in E. coli and their potential use for cellular disruption. In the systems described here the genetic information for lysis would be carried within the microbial host, either integrated or natur
Publikováno v:
Bioseparation. 1(1)
Simulation and optimization of continuous affinity recycle extraction (CARE), a protein purification unit operation based on protein adsorption to solid phase adsorbents, is described in this paper. Rather than packing conventional adsorbent particle
Publikováno v:
Journal of General Microbiology. 96:415-422
SUMMARY: The effects of different nutrient limitations on the production of the two enzymes of gramicidin S biosynthesis were studied during continuous culture of Bacillus brevis. Gramicidin S synthetases I and II were produced in the chemostat under
Autor:
F. Acevedo, C. L. Cooney
Publikováno v:
European Journal of Applied Microbiology. 2:9-17
The production of penicillin amidase fromBacillus megaterium ATCC 14945 was examined in a sulfur-limited chemostat. Below 50% of the maximum growth rate, enzyme production was independent of dilution rate; above this point production decreased as gro