Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C. L. Chio"'
Autor:
H. H. M. Van Tol, Marc G. Caron, M. F. Piercey, M. E. Lajiness, C. L. Chio, C. A. Tamminga, A. Carlsson, J. C. Schwartz, Rita M. Huff
Publikováno v:
Clinical Neuropharmacology. 18:S25-S33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7d4bdcd3bf24e3a7da778388c9bc2ec
https://doi.org/10.1097/00002826-199501001-00004
https://doi.org/10.1097/00002826-199501001-00004
D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells
Publikováno v:
Journal of Biological Chemistry. 269:11813-11819
A Chinese hamster ovary (CHO) cell line stably expressing a recombinant human D4 dopamine receptor made from a synthetic gene has been used to determine potential D4-mediated signaling events. We designed and synthesized a modified gene coding for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcea41444283b38b1419c0eaa75c35e
https://doi.org/10.1016/s0021-9258(17)32645-5
https://doi.org/10.1016/s0021-9258(17)32645-5
Autor:
R Huff, R TenBrink, Robert L Hoffman, N R Higdon, N B Ghazal, C L Bergh, R B McCall, Michael D. Ennis, C L Chio, E Hall, K Meisheri
Publikováno v:
Cephalalgia : an international journal of headache. 22(10)
The present study describes the preclinical pharmacology of a highly selective 5-HT1Dreceptor agonist PNU-142633. PNU-142633 binds with a Ki of 6 nM at the human 5-HT1Dreceptor and a Ki of > 18 000 nM at the human 5-HT1B receptor. The intrinsic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b671ef13fee7f8a28a64c549725f0bfd
https://pubmed.ncbi.nlm.nih.gov/12485205
https://pubmed.ncbi.nlm.nih.gov/12485205
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa3f1ace2908c44368a443f6a8f37dc5
https://pubmed.ncbi.nlm.nih.gov/9327937
https://pubmed.ncbi.nlm.nih.gov/9327937
D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells
Publikováno v:
The Journal of biological chemistry. 269(16)
A Chinese hamster ovary (CHO) cell line stably expressing a recombinant human D4 dopamine receptor made from a synthetic gene has been used to determine potential D4-mediated signaling events. We designed and synthesized a modified gene coding for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfb85ebc626fcc5ab2cea5dc7af3f2f2
https://pubmed.ncbi.nlm.nih.gov/7512953
https://pubmed.ncbi.nlm.nih.gov/7512953
Publikováno v:
Molecular pharmacology. 45(1)
Recombinant rat D3 dopamine receptors heterologously expressed in Chinese hamster ovary (CHO) cells are functionally coupled to endogenous G proteins. The affinity of the receptors for agonists is regulated by guanine nucleotides in the same manner a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7dc105191bf0860d6e02708639ea9c46
https://pubmed.ncbi.nlm.nih.gov/8302280
https://pubmed.ncbi.nlm.nih.gov/8302280
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(3)
Several neurotransmitters that act through G protein-linked receptors have been shown to affect the growth rate of dividing cells. An analysis of the early signaling events that mediate this response revealed some novel activities for G protein-linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::639e5d4d8f838ff30cb4bcc8dbaff4f0
https://pubmed.ncbi.nlm.nih.gov/7903393
https://pubmed.ncbi.nlm.nih.gov/7903393
Publikováno v:
Nature. 343(6255)
OVEREXPRESSION of the D2dopamine receptor has been proposed to be part of the pathology of schizophrenia1.The isolation of a D2dopamine receptor clone has assisted the molecular characterization of D2 receptors2. We have now isolated an identical rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89acd19d611eff80a6e67cb70cf9da43
https://pubmed.ncbi.nlm.nih.gov/2137198
https://pubmed.ncbi.nlm.nih.gov/2137198
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