Zobrazeno 1 - 10
of 62
pro vyhledávání: '"C. L. Bashford"'
Autor:
Peter W. Andrew, C. L. Bashford, Charles A. Pasternak, Timothy J. Mitchell, Yuri E. Korchev, C Pederzolli, Peter J. Morgan
Publikováno v:
Biochemical Journal. 329:571-577
Pneumolysin is one of the family of thiol-activatable, cytolytic toxins. Within these toxins the amino acid sequence Trp-Glu-Trp-Trp is conserved. Mutations made in this region of pneumolysin, residues 433-436 inclusive, did not affect cell binding o
Autor:
M. J. Lab, Elena V. Sviderskaya, Dorothy C. Bennett, I. Vodyanoy, C. L. Bashford, Yuri E. Korchev, M. Milovanovic
Publikováno v:
Journal of Microscopy. 188:17-23
A specialized scanning ion conductance microscope (SICM) for imaging living cells has been developed from a conventional patch-clamp apparatus, which uses a glass micropipette as the sensitive probe. In contrast with other types of scanning probe mic
Autor:
Noriyasu Nagaoka, N Reber, Masaharu Asano, C.A. Pasternak, Hideki Omichi, Hitoshi Kubota, V. Ang, Reimar Spohr, Ryoichi Katakai, C. L. Bashford, G.M. Alder, A. Wolf, Masaru Yoshida
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 131:350-356
Heavy ion beams with energy in the order of 10 MeV/n were irradiated onto polyethylene terephthalate (PET) and polydiethyleneglycol-bis-allylcarbonate commercially known as CR-39 for producing organic porous membranes. The condition to obtain cylindr
Autor:
Charles A. Pasternak, Donald T. Edmonds, K Nandi, C. L. Bashford, Aleksey V. Zima, P Y Apel, A.A. Lev, G. M. Alder, Yuri E. Korchev
Publikováno v:
The FASEB Journal. 11:600-608
Fluctuation of ion current, between a high conductance and a low conductance state, through biological ion channels and pores is assumed to arise from conformational changes between an "open" and a "closed" configuration. Here we offer an additional
Autor:
C. L. Bashford, A. MacKinnon, Charles A. Pasternak, L.G. Fulford, Cecilia Pederzolli, Yuri E. Korchev, E. Kovacs, G. M. Alder
Publikováno v:
Journal of Membrane Biology. 150:37-45
Nonelectrolytes such as polyethylene glycols (PEG) and dextrans (i) promote the association of S. aureus alpha-toxin with liposomes (shown by Coomassie staining) and (ii) enhance the rate and extent of calcein leakage from calcein-loaded liposomes; s
Autor:
M. Milovanovich, Donald T. Edmonds, G.M. Alder, P. Yu. Apel, N.I. Zhitariuk, A.A. Lev, C.A. Pasternak, G. Lowe, T.K. Rostovtseva, C. L. Bashford, Yuri E. Korchev, C.W. Pitt
Publikováno v:
Radiation Measurements. 25:675-683
Ion current through individual pores in track-etched polyethyleneterephthalate filters can have the following properties which are shared by a number of biological ion channels: 1. 1) selectivity for cations over anions, or vice versa depending on th
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 77:119-124
The flow of electrolytes and non-electrolytes through narrow pores (about 1 nm radius) in synthetic membranes is reported. The characteristic features of such flow are the following. (i) The electrical conductivity displays fluctuations typical of si
Autor:
C. L. Bashford, T.K. Rostovtseva, A.A. Lev, Charles A. Pasternak, Donald T. Edmonds, Y. E. Korchev
Publikováno v:
Proceedings of the Royal Society of London. Series B: Biological Sciences. 252:187-192
Ions flowing through purely synthetic filters made of polyethylene terephthalate which have been etched to produce narrow pores show: (i) rapid transitions between a high-conducting and a low-conducting state; (ii) selectivity of ion flow; and (iii)
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1061:111-120
Leakage of ions and low-molecular-weight metabolites from Lettre cells is induced by synthetic melittin, as effectively as by melittin isolated from bee venom; in each case leakage is inhibited by Ca 2+ , Zn 2+ or H + . Inhibition of leakage by dival
Publikováno v:
Toxicon. 28:477-491
Three quite different bacterial toxins (S. aureus alpha-toxin, C. perfringens theta-toxin and E. coli haemolysin) induce the leakage of phosphorylated metabolites from Lettre cells and of calcein from liposomes; in each case leakage is inhibited by Z