Výsledky vyhledávání - "C. L. Barsuhn"

Influence of organic acid excretion on cuticle pH and drug absorption by Haemonchus contortus

Autor: Timothy G. Geary, C. L. Barsuhn, David P. Thompson, Eileen M. Thomas, Sandra M. Sims, N.F.H. Ho, J. S. Day

Publikováno v: International Journal for Parasitology. 26:25-35

To determine if a cuticle microenvironment pH is maintained by adult Haemonchus contortus , organic acid excretion kinetics and absorption kinetics of selected model weak acids and a weak base were measured in incubation media that varied in buffer c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5505798214eec0610e4f12ce3e59d9ac
https://doi.org/10.1016/0020-7519(95)00113-1

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Interrelationships among physicochemical properties, absorption and anthelmintic activities of 2-desoxoparaherquamide and selected analogs

Autor: S. S. Johnson, Timothy G. Geary, C. L. Barsuhn, David P. Thompson, B. H. Lee, R. M. Zaya, George A. Conder, R. A. Martin, Thomas J. Vidmar, N.F.H. Ho, J. P. Davis, J. S. Day, E. M. Coscarelli

Publikováno v: Journal of veterinary pharmacology and therapeutics. 27(3)

The interrelationships between physicochemical properties, absorption and potency of 2-desoxoparaherquamide and five analogs, representing a new anthelmintic class, were evaluated in in vitro and in vivo assays. At pH 7.5, rates of drug absorption by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33564b7cec31dcadc5a37a217e390e02
https://pubmed.ncbi.nlm.nih.gov/15189303

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Increased lipophilicity and subsequent cell partitioning decrease passive transcellular diffusion of novel, highly lipophilic antioxidants

Autor: G A, Sawada, C L, Barsuhn, B S, Lutzke, M E, Houghton, G E, Padbury, N F, Ho, T J, Raub

Publikováno v: The Journal of pharmacology and experimental therapeutics. 288(3)

Oxidative stress is considered a cause or propagator of acute and chronic disorders of the central nervous system. Novel 2, 4-diamino-pyrrolo[2,3-d]pyrimidines are potent inhibitors of iron-dependent lipid peroxidation, are cytoprotective in cell cul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::316a9bdd761d4fb88ac7cc0794c817cc
https://pubmed.ncbi.nlm.nih.gov/10027873

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Transcellular permeability of chlorpromazine demonstrating the roles of protein binding and membrane partitioning

Autor: G A, Sawada, N F, Ho, L R, Williams, C L, Barsuhn, T J, Raub

Publikováno v: Pharmaceutical research. 11(5)

Transcellular permeability of the neuroleptic-anesthetic chlorpromazine (CPZ) was examined using a cell type (MDCK) that forms a confluent monolayer of polarized cells resulting in distinct apical (AP) and basolateral (BL) membrane domains separated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04f88322143949f8b34a29fe07859baf
https://pubmed.ncbi.nlm.nih.gov/8058634

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Kinetics of the metal-exchange reaction between N,N'-bis(2-picolyl)ethylenediaminenickel(II) and copper(II)

Autor: R. K. Steinhaus, C. L. Barsuhn

Publikováno v: Inorganic Chemistry. 13:2922-2929

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2313934fb2191aaf9a86372bf396048
https://doi.org/10.1021/ic50142a030

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ChemInform Abstract: KINETICS OF THE METAL-EXCHANGE REACTION BETWEEN N,N′-BIS(2-PICOLYL)ETHYLENEDIAMINENICKEL(II) AND COPPER(II)

Autor: R. K. STEINHAUS, C. L. BARSUHN

Publikováno v: Chemischer Informationsdienst. 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b7fd3a9571acc1ab2e08ebe61dd2fb1
https://doi.org/10.1002/chin.197507414

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