Zobrazeno 1 - 9
of 9
pro vyhledávání: '"C. L. A. Mann"'
Autor:
L. Pepper, W. E. R. Ollier, M. B. Davies, Mike Boggild, Jane Worthington, Anthony A. Fryer, Carolyn A Young, C. L. A. Mann, Rachelle Donn, Richard C. Strange, Clive Hawkins, Wendy Thomson, S. J. M. Weatherby, Peter W. Jones
Publikováno v:
Journal of Neurology. 248:304-310
The association between susceptibility to multiple sclerosis (MS) and the class II MHC allele HLA-DRB1*15 is well established although a possible relationship between this allele and outcome in MS is less clear. HLA-DRB1 typing was performed on 375 u
Autor:
Carolyn A Young, C. L. A. Mann, Richard C. Strange, W. E. R. Ollier, M. B. Davies, S. J. M. Weatherby, Mike Boggild, Anthony A. Fryer, D. Carthy, Clive Hawkins
Publikováno v:
Scopus-Elsevier
Allelic variants of the apolipoprotein E (APOE) gene influence the course of several neurological diseases. In multiple sclerosis the concentration of APOE in cerebrospinal fluid and its intrathecal synthesis is reduced. Specific isoforms of APOE may
Autor:
W. E. R. Ollier, Ian V. Hutchinson, Rachelle Donn, Mike Boggild, Richard C. Strange, C Pickard, P. Sinnott, Clive Hawkins, C. L. A. Mann
Publikováno v:
Journal of Neuroimmunology. 101:207-210
Interleukin-10 (IL10) is an anti-inflammatory cytokine which may modulate disease expression in multiple sclerosis (MS). Three dimorphic polymorphisms within the IL10 promoter region at positions - 1082, -819 and -519 have previously been identified.
Autor:
W. E. R. Ollier, Richard C. Strange, John Woolmore, C. L. A. Mann, Mike Boggild, Anthony A. Fryer, S. J. M. Weatherby, Clive Hawkins, J. M. Partridge, D. J. Highland
Publikováno v:
Neurology. 62:2323-2325
Multiple sclerosis (MS) risk is determined by environment and genes. The authors investigated in 419 cases and 422 controls if polymorphism in the vitamin D receptor (VDR), melanocortin-1 receptor (MC1R), and tyrosinase (TYR) genes is linked with MS
Publikováno v:
Obesity Surgery. 3:271-274
A prospective study of biochemical changes after vertical banded gastroplasty for morbid obesity, in 94 patients (10 males and 84 females, ages ranging from 18 to 59 years) has been carried out. Liver function tests and electrolyte estimations were p
Autor:
M. B. Davies, Mike Boggild, C. Ko Ko, Peter W. Jones, Anthony A. Fryer, Valerie L. Stevenson, C. L. A. Mann, Alan J. Thompson, Richard C. Strange, Clive Hawkins, Siobhan M. Leary
Publikováno v:
Journal of neuroimmunology. 129(1-2)
We studied the association between clinical outcome in MS and allelic variants single nucleotide polymorphisms (SNPs) of interleukin-1α (IL-1α), IL-1β and a variable number tandem repeat (VNTR) in IL-1 receptor antagonist (IL-1RN). A total of 377
Autor:
M. B. Davies, C. L. A. Mann, S. J. M. Weatherby, N. Haq, Clive Hawkins, Anthony A. Fryer, Richard C. Strange
Publikováno v:
Journal of neurology. 247(6)
Autor:
C. L. A. Mann, Anthony A. Fryer, S M Leary, S. J. M. Weatherby, Richard C. Strange, Valerie L. Stevenson, Clive Hawkins, Aj Thompson
Recent reports, primarily in patients with secondary progressive and relapsing-remitting multiple sclerosis have suggested that the apolipoprotein (APOE) e4 allele may be associated with a worse prognosis.1-3 The e class of APOE is involved in lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c28d00f2269eea8da497b39addabc9
https://europepmc.org/articles/PMC1736883/
https://europepmc.org/articles/PMC1736883/
Autor:
Peter W. Jones, Julie Alldersea, C. Ko Ko, M. B. Davies, Mike Boggild, Richard C. Strange, Anthony A. Fryer, Carolyn A Young, Clive Hawkins, C. L. A. Mann
Publikováno v:
Neurology. 54(3)
Background: Oxidative stress has been implicated in inflammatory demyelination. The glutathione S-transferase (GST) supergene family encodes isoenzymes that appear to be critical in protection against oxidative stress. Certain GST loci are polymorphi