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In vivo T cell depletion with pretransplant anti-thymocyte globulin reduces graft-versus-host disease without increasing relapse in good risk myeloid leukemia patients after stem cell transplantation from matched related donors

Autor: Rudolf Erttmann, W Krüger, Ulrika M. Schade, F. Tögel, H Renges, N Stute, J Rischewski, S Sonnenberg, H Fiegel, F Ayuk, Tatjana Zabelina, N Kröger, C Löliger, A R Zander

Publikováno v: Bone Marrow Transplantation. 29:683-689

One-hundred and two patients with good risk myeloid leukemia (CML first chronic phase or AML first CR) were transplanted from HLA-related donors after conditioning with (n = 45) or without anti-thymocyte globulin (ATG) (n = 57). One graft failure was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7688622c367fd8ffeaa01d2dc5fb518e
https://doi.org/10.1038/sj.bmt.1703530

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Anti-Thymocyte-Globulin as part of the preparative regimen prevents graft failure and severe Graft versus Host disease (GvHD) in allogeneic stem cell transplantation from unrelated donors

Autor: William Krüger, Tatjana Zabelina, C Löliger, Nicole Jaburg, Nicolaus Kröger, M Dürken, Axel R. Zander, Helmut Renges, Philipe Schafhausen, Friedrich Graf von Finkenstein, R. Erttmann, Norbert Stute, Hartmut Kabisch

Publikováno v: Annals of Hematology. 80:209-215

To reduce the incidence of GvHD and the rate of graft failure in unrelated stem cell transplantation, we incorporate anti-thymocyte globulin in the preparative regimen in 98 patients with hematological or inherited storage disease. The median age was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6267ca82add4bf9bd8b7a9742efffeca
https://doi.org/10.1007/s002770000269

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Comparison of Progenitor Cell Collection on Day 4 or Day 5 After Steady-State Stimulation with G-CSF Alone in Breast Cancer Patients: Influence on CD34+Cell Yield, Subpopulation, and Breast Cancer Cell Contamination

Autor: William Krüger, C Löliger, Nicolaus Kröger, Claudia Rauhoft, Axel R. Zander, Helmut Renges, W. Zeller

Publikováno v: Journal of Hematotherapy & Stem Cell Research. 9:111-117

To determine the influence of apheresis timing on CD34+ cell yield, subpopulation, and breast cancer cell contamination, 48 women with breast cancer were stimulated from steady-state hematopoiesis in a prospective but nonrandomized study with 2 x 5 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b012a2a1626e108cd8790ed70d03cb
https://doi.org/10.1089/152581600319694

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Physiological features of primary cultures and subcultures of human retinal pigment epithelial cells before and after cryopreservation for cell transplantation

Autor: Gisbert Richard, A S Ventura, R Krüger, M. Valtink, Katrin Engelmann, C Löliger, Olaf Strauss

Publikováno v: Graefe's Archive for Clinical and Experimental Ophthalmology. 237:1001-1006

· Background: One striking disadvantage of in vitro culturing of human retinal pigment epithelial (RPE) cells is the loss of epithelial differentiation and specific cell function during culture. This may be one of the main reasons for the failure of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c82e7c207a36ba244aaaed4d650eba5
https://doi.org/10.1007/s004170050336

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Improved outcome in haemophagocytic lymphohistiocytosis after bone marrow transplantation from related and unrelated donors: a single-centre experience of 12 patients

Autor: William Krüger, N Kröger, C Löliger, H H Hellwege, Rudolf Erttmann, P. Bieling, Gritta Janka, M Dürken, Axel R. Zander, E. M. Schneider, Hartmut Kabisch, Martin A. Horstmann

Publikováno v: British Journal of Haematology. 106:1052-1058

Haemophagocytic lymphohistiocytosis (HLH) is an autosomal recessive disease with histiocytic and lymphocytic infiltrations in multiple organs. Cure seems possible only by allogeneic bone marrow transplantation (BMT), but matched sibling donors (MSD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d6e7560a43d4e3ccdc991063864cdde
https://doi.org/10.1046/j.1365-2141.1999.01625.x

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Natürliche humane IgM-Antikörper in der Therapie des Neuroblastoms: Vorläufige Ergebnisse einer Phase I/II-Therapiestudie

Autor: Carl-Wilhelm Vogel, C. Löliger, Reinhard Bredehorst, C. Schmitt, K. David, J. Schrum, Rudolf Erttmann, J. Hiller

Publikováno v: Klinische Pädiatrie. 211:314-318

Background Sera from healthy individuals contain natural IgM antibodies (anti-NB-Ab) cytotoxic to neuroblastoma (NB) cells. In contrast to healthy children the prevalence of anti-NB-Ab in sera of NB patients is low. Binding of anti-NB-Ab to the NB ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d14986276f1a7e6da55d5798c37194f
https://doi.org/10.1055/s-2008-1043807

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The impact of HLA on long-term outcome after thymectomy for myasthenia gravis

Autor: J. R. Izbicki, C. Löliger, A. Machens, Uwe Pichlmeier, Christoph Busch, Th. Emskötter

Publikováno v: Journal of Neuroimmunology. 88:177-181

In a retrospective series of 86 patients with myasthenia gravis, the only factors predictive of improvement in muscular strength after transsternal thymectomy were preoperative severity of myasthenia (90% versus 54%, p =0.0014) and HLA-B8 (79% versus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcbe9f364fb6f1ee88b7a1abff4c083
https://doi.org/10.1016/s0165-5728(98)00120-9

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