Zobrazeno 1 - 10
of 115
pro vyhledávání: '"C. López-Berges"'
Autor:
Jesús F. San Miguel, Alfonso García de Coca, Natalia de las Heras, Magdalena Sierra, María-Belén Vidriales, Rebeca Cuello, Ramón García-Sanz, José J. Pérez, Emilia Pardal, Bruno Paiva, José Augusto Evangelho Hernandez, Josefina Galende, M C López-Berges, Enrique M. Ocio, Maria-Victoria Mateos, Abelardo Bárez, Lissbett Suárez, José L. Alonso
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The clinical value of multiparameter flow cytometry (MFC) immunophenotyping in primary or light chain amyloidosis (AL) remains unknown. We studied 44 consecutive bone marrow samples from newly diagnosed patients with amyloidosis; 35 patients with AL
Autor:
C S Osuna, J M Hernández, María Tabernero, Ramón García-Sanz, Miranda Romero, Manuel Giralt, Norma C. Gutiérrez, J F San Miguel, M C López-Berges, Ana Belén Espinosa, M. Barbón, Ana Rasillo, A. Orfao, José J. Pérez, Daniel Primo, J M Sayagués
Publikováno v:
Leukemia. 19:713-720
Philadelphia-positive (Ph(+)) B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a genetically heterogeneous disease with a very poor prognosis. In this study, we analyzed the frequency of supernumerary Ph, trisomy 8, monosomy 7, and del(9p21
Autor:
Josefina Galende, J F San Miguel, J. Fernández-Calvo, J. A. Portero, Maria Isabel González-Fraile, Ramón García-Sanz, Gema Mateo, M C López-Berges, J M Hernández, Francisco Ortega, Abelardo Bárez, N. de las Heras, A. Orfao
Publikováno v:
International Journal of Cancer. 112:884-889
Although multiple myeloma (MM) is predominantly a disease of the elderly, few studies have focused on the identification of prognostic factors in this group of patients. Four hundred twenty five MM patients >65 years were uniformly treated with chemo
Autor:
M C López-Berges, M A García-Marcos, Marcos González, Alberto Orfao, Julia Almeida, Guillermo Martín-Núñez, M. Barbón, David Gonzalez, Ana Balanzategui, J. Fernández-Calvo, Teresa Vallespi, Jesus-Maria Hernandez, Alejandro Martín, Jesús F. San Miguel, Maria-Luz Sanchez, Josep F. Nomdedeu, Pilar de la Fuente
Publikováno v:
Blood. 102:2994-3002
Leukemic B-chronic lymphoproliferative disorders (B-CLPDs) are generally believed to derive from a monoclonal B cell; biclonality has only occasionally been reported. In this study, we have explored the incidence of B-CLPD cases with 2 or more B-cell
Autor:
Joan Bladé, Luis Palomera, Julia Almeida, C. López-Berges, José L. Hernández, Maria Jesus Moro, Dolores Caballero, Joaquín Díaz-Mediavilla, Alberto Orfao, J. Fernández-Calvo, Jesús F. San Miguel, Gema Mateo
Publikováno v:
Blood. 99:1853-1856
Multiparametric immunophenotyping can be a sensitive method for analyzing the plasma cell (PC) compartment in patients with multiple myeloma because it discriminates between myelomatous and normal PCs. Using this approach, we compared the efficacy of
Autor:
C. López-Berges, Marcos González, Consuelo del Cañizo, Jesús F. San Miguel, Norma C. Gutiérrez, Joaquín Díaz-Mediavilla, José J. Pérez, Alberto Orfao, M J Calmuntia, María Belén Vidriales, Fernando Ramos
Publikováno v:
Blood. 98:1746-1751
Early response to therapy is one of the most important prognostic factors in acute leukemia. It is hypothesized that early immunophenotypical evaluation may help identify patients at high risk for relapse from those who may remain in complete remissi
Autor:
Gema Mateo, Marcos González, J F San Miguel, Ramón García-Sanz, A. Orfao, I. Alaejos, María Dolores Tabernero, Ana Rasillo, A. M. Bortoluci, J M Sayagués, M C López-Berges, M.L. Márquez García
Publikováno v:
Leukemia. 15:406-414
The Philadelphia chromosome (Ph+) reflects a balanced reciprocal translocation between the long arms of chromosomes 9 and 22 [t(9;22)(q34;q11.2] involving the BCR and ABL genes. At present, detection of BCR/ABL gene rearrangements is mandatory in pre
Autor:
A. Orfao, A. Martínez, M J Calmuntia, Francisco Ortega, M B Vidriales, Juana Ciudad, M C López-Berges, M. D. Caballero, J F San Miguel, Moro Mj
Publikováno v:
Cytometry. 38:70-75
During conventional follow-up of patients with acute myeloid leukemia (AML), the emergence of cytopenias is considered to be a sign of impending relapse, and it represents an example of how leukemic hematopoiesis affects normal hemopoietic differenti
Autor:
Marcos González, A. Orfao, M.C. del Cañizo, Lourdes Vázquez, M C López-Berges, J F San Miguel, Aurelio López, J. J. M. Van Dongen, Juana Ciudad, M. A. Garcia Marcos
Publikováno v:
British Journal of Haematology. 104:695-705
Immunophenotypic investigation of minimal residual disease (MRD) has traditionally been based on the investigation of phenotypic aberrants at diagnosis to be used later as a target for MRD detection. This approach has several shortcomings (it is only
Autor:
Maria Luisa Najera, J F San Miguel, A. Durán, J M Hernández, M C López-Berges, María Tabernero, M. Garcia-Isidoro, A. Martínez, M. A. Garcia Marcos, Juan Luis García, A. Orfao
Publikováno v:
Annals of Hematology. 74:209-214
In the present study we have used FISH to analyze the incidence of trisomy 8 in acute leukemias following either a primary myeloproliferative disorder (MPD) or a myelodysplastic syndrome (MDS) and correlated it with both the immunophenotype and the c