Zobrazeno 1 - 10
of 54
pro vyhledávání: '"C. Kuijper"'
Autor:
Ronald A. M. Buijsen, Linda M. van der Graaf, Elsa C. Kuijper, Barry A. Pepers, Elena Daoutsali, Lotte Weel, Vered Raz, David A. Parfitt, Willeke M. C. van Roon-Mom
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1933 (2024)
Antisense technology demonstrates significant potential for addressing inherited brain diseases, with over a dozen products already available and numerous others in the development pipeline. The versatility of differentiating induced pluripotent stem
Externí odkaz:
https://doaj.org/article/327ffa18f86647849ab4e8f6806628e2
Autor:
Elsa C. Kuijper, Maurice Overzier, Ernst Suidgeest, Oleh Dzyubachyk, Cécile Maguin, Jean-Baptiste Pérot, Julien Flament, Yavuz Ariyurek, Hailiang Mei, Ronald A.M. Buijsen, Louise van der Weerd, Willeke van Roon-Mom
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106368- (2024)
In Huntington disease, cellular toxicity is particularly caused by toxic protein fragments generated from the mutant huntingtin (HTT) protein. By modifying the HTT protein, we aim to reduce proteolytic cleavage and ameliorate the consequences of muta
Externí odkaz:
https://doaj.org/article/0b4874be3df4497fb539494749184266
Autor:
Steven C. Kuijper, Marieke Pape, Nadia Haj Mohammad, Theo van Voorthuizen, Rob H. A. Verhoeven, Hanneke W. M. van Laarhoven
Publikováno v:
International Journal of Cancer, 152(6), 1202-1209. Wiley-Liss Inc.
Kuijper, S C, Pape, M, Haj Mohammad, N, van Voorthuizen, T, Verhoeven, R H A & van Laarhoven, H W M 2023, ' SOURCE beyond first-line : A survival prediction model for patients with metastatic esophagogastric adenocarcinoma after failure of first-line palliative systemic therapy ', International Journal of Cancer, vol. 152, no. 6, pp. 1202-1209 . https://doi.org/10.1002/ijc.34385
Kuijper, S C, Pape, M, Haj Mohammad, N, van Voorthuizen, T, Verhoeven, R H A & van Laarhoven, H W M 2023, ' SOURCE beyond first-line : A survival prediction model for patients with metastatic esophagogastric adenocarcinoma after failure of first-line palliative systemic therapy ', International Journal of Cancer, vol. 152, no. 6, pp. 1202-1209 . https://doi.org/10.1002/ijc.34385
Prior models have been developed to predict survival for patients with esophagogastric cancer undergoing curative treatment or first-line chemotherapy (SOURCE models). Comprehensive clinical prediction models for patients with esophagogastric cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc286d0b7634d537847a58c7d02245a1
http://www.scopus.com/inward/record.url?scp=85146532112&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85146532112&partnerID=8YFLogxK
Autor:
Ivo S. Hansen, Lisette Krabbendam, Jochem H. Bernink, Fabricio Loayza-Puch, Willianne Hoepel, Johan A. van Burgsteden, Elsa C. Kuijper, Christianne J. Buskens, Willem A. Bemelman, Sebastiaan A. J. Zaat, Reuven Agami, Gestur Vidarsson, Gijs R. van den Brink, Esther C. de Jong, Manon E. Wildenberg, Dominique L. P. Baeten, Bart Everts, Jeroen den Dunnen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Dendritic cells (DC) are important for maintaining immune homeostasis in the gut, but how they promote intestinal inflammation upon bacterial infection is still unclear. Here the authors show that IgA immune complexes induce proinflammatory cytokine
Externí odkaz:
https://doaj.org/article/292a58835f16458d974a1336ef0a74da
Autor:
Steven C. Kuijper, Marieke Pape, Pauline A. J. Vissers, Paul M. Jeene, Ewout A. Kouwenhoven, Nadia Haj Mohammad, Jelle P. Ruurda, Meindert N. Sosef, Rob H. A. Verhoeven, Hanneke W. M. van Laarhoven
Publikováno v:
International Journal of Cancer, 153(1), 33-43. Wiley-Liss Inc.
Kuijper, S C, Pape, M, Vissers, P A J, Jeene, P M, Kouwenhoven, E A, Haj Mohammad, N, Ruurda, J P, Sosef, M N, Verhoeven, R H A & van Laarhoven, H W M 2023, ' Trends in best-case, typical and worst-case survival scenarios of patients with non-metastatic esophagogastric cancer between 2006 and 2020 : A population-based study ', International Journal of Cancer, vol. 153, no. 1, pp. 33-43 . https://doi.org/10.1002/ijc.34488
Kuijper, S C, Pape, M, Vissers, P A J, Jeene, P M, Kouwenhoven, E A, Haj Mohammad, N, Ruurda, J P, Sosef, M N, Verhoeven, R H A & van Laarhoven, H W M 2023, ' Trends in best-case, typical and worst-case survival scenarios of patients with non-metastatic esophagogastric cancer between 2006 and 2020 : A population-based study ', International Journal of Cancer, vol. 153, no. 1, pp. 33-43 . https://doi.org/10.1002/ijc.34488
New treatment options and centralization of surgery have improved survival for patients with non-metastatic esophageal or gastric cancer. It is unknown, however, which patients benefitted the most from treatment advances. The aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffb503e8269e45c680a56e27a8720db
https://research.vumc.nl/en/publications/a8617038-5bf7-47bc-8db3-01b8276e29bc
https://research.vumc.nl/en/publications/a8617038-5bf7-47bc-8db3-01b8276e29bc
Autor:
Paul M. Jeene, Steven C. Kuijper, Héctor G. van den Boorn, Sherif Y. El Sharouni, Pètra M. Braam, Vera Oppedijk, Rob H. A. Verhoeven, Maarten C. C. M. Hulshof, Hanneke W. M. van Laarhoven
Publikováno v:
Acta Oncologica, 61, 7, pp. 849-855
Jeene, P M, Kuijper, S C, van den Boorn, H C G, el Sharouni, S Y, Braam, P T M, Oppedijk, V, Verhoeven, R H A, Hulshof, M C C M & van Laarhoven, H W M 2022, ' Improving survival prediction of oesophageal cancer patients treated with external beam radiotherapy for dysphagia ', Acta Oncologica, vol. 61, no. 7, pp. 849-855 . https://doi.org/10.1080/0284186X.2022.2079385
Acta Oncologica, 61, 849-855
Acta Oncologica, 61(7), 849-855. Informa Healthcare
Jeene, P M, Kuijper, S C, van den Boorn, H C G, el Sharouni, S Y, Braam, P T M, Oppedijk, V, Verhoeven, R H A, Hulshof, M C C M & van Laarhoven, H W M 2022, ' Improving survival prediction of oesophageal cancer patients treated with external beam radiotherapy for dysphagia ', Acta Oncologica, vol. 61, no. 7, pp. 849-855 . https://doi.org/10.1080/0284186X.2022.2079385
Acta Oncologica, 61, 849-855
Acta Oncologica, 61(7), 849-855. Informa Healthcare
Contains fulltext : 251435.pdf (Publisher’s version ) (Open Access) INTRODUCTION: The recent POLDER trial investigated the effects of external beam radiotherapy (EBRT) on dysphagia caused by incurable oesophageal cancer. An estimated life expectanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5532339a867c13d20f96cabe500097f7
https://doi.org/10.1080/0284186x.2022.2079385
https://doi.org/10.1080/0284186x.2022.2079385
Autor:
Marieke Pape, Linde M. Veen, Thom M. Smit, Steven C. Kuijper, Pauline A.J. Vissers, Elisabeth D. Geijsen, Peter S.N. van Rossum, Mirjam A.G. Sprangers, Sarah Derks, Rob H.A. Verhoeven, Hanneke W.M. van Laarhoven
Publikováno v:
Pape, M, Veen, L M, Smit, T M, Kuijper, S C, Vissers, P A J, Geijsen, E D, van Rossum, P S N, Sprangers, M A G, Derks, S, Verhoeven, R H A & van Laarhoven, H W M 2023, ' Late Toxicity and Health-Related Quality of Life Following Definitive Chemoradiotherapy for Esophageal Cancer : A Systematic Review and Meta-analysis ', International Journal of Radiation Oncology Biology Physics . https://doi.org/10.1016/j.ijrobp.2023.05.025
Purpose: Definitive chemoradiotherapy (dCRT) is a treatment option with curative intent for patients with esophageal cancer that could result in late toxicities and affect health-related quality of life (HRQoL). This study aimed to review the literat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d86235c7072466b2ff705aae970e42
https://research.vumc.nl/en/publications/3e030dd4-63ec-4136-964a-39eb062a903e
https://research.vumc.nl/en/publications/3e030dd4-63ec-4136-964a-39eb062a903e
Publikováno v:
Prevention science : the official journal of the Society for Prevention Research.
The prevalence of bullying worldwide is high (UNESCO, 2018). Over the past decades, many anti-bullying interventions have been developed to remediate this problem. However, we lack insight into for whom these interventions work and what individual in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84c1eb138af4e254050d1f109a420b87
https://pubmed.ncbi.nlm.nih.gov/35796879
https://pubmed.ncbi.nlm.nih.gov/35796879
Autor:
Marieke, Pape, Steven C, Kuijper, Pauline A J, Vissers, Laurens V, Beerepoot, Geert-Jan, Creemers, Hanneke W M, van Laarhoven, Rob H A, Verhoeven
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 20(12)
In recent years, clinical trials have shown improved survival of patients with metastatic esophageal or gastric cancer. The number of patients participating in clinical trials is limited, and survival improvements observed from clinical trials are un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10a9148f9af88a9329d53e25b5045008
https://pubmed.ncbi.nlm.nih.gov/36509070
https://pubmed.ncbi.nlm.nih.gov/36509070
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071620090
Methods in Molecular Biology ISBN: 9781071620090
The use of antisense oligonucleotides (AONs) is a promising therapeutic strategy for central nervous system disorders. However, the delivery of AONs to the central nervous system is challenging because their size does not allow them to diffuse over t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9cdd8a1119c84c49e6f2b4c2db5f43
https://europepmc.org/articles/PMC9703226/
https://europepmc.org/articles/PMC9703226/