Zobrazeno 1 - 10
of 921
pro vyhledávání: '"C. Kraft"'
Publikováno v:
Heliyon, Vol 7, Iss 4, Pp e06714- (2021)
Salmonella spp. remains a wide-spread pathogen among pig herds and its control has major impact on food borne Salmonella infections in humans. The objective of the study was to investigate the influence of an Enterisol® Ileitis vaccination on Salmon
Externí odkaz:
https://doaj.org/article/102e6c261c2e4249b169850df2810957
Autor:
Marcos C. Miranda, Elizabeth Kepl, Mary Jane Navarro, Chengbo Chen, Max Johnson, Kaitlin R. Sprouse, Cameron Stewart, Anne Palser, Adian Valdez, Deleah Pettie, Claire Sydeman, Cassandra Ogohara, John C. Kraft, Minh Pham, Michael Murphy, Sam Wrenn, Brooke Fiala, Rashmi Ravichandran, Daniel Ellis, Lauren Carter, Davide Corti, Paul Kellam, Kelly Lee, Alexandra C. Walls, David Veesler, Neil P. King
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract We previously described a two-component protein nanoparticle vaccine platform that displays 60 copies of the SARS-CoV-2 spike protein RBD (RBD-NP). The vaccine, when adjuvanted with AS03, was shown to elicit robust neutralizing antibody and
Externí odkaz:
https://doaj.org/article/649dcf2c588340c39547078121604655
Autor:
Jared Adolf-Bryfogle, Jason W Labonte, John C Kraft, Maxim Shapovalov, Sebastian Raemisch, Thomas Lütteke, Frank DiMaio, Christopher D Bahl, Jesper Pallesen, Neil P King, Jeffrey J Gray, Daniel W Kulp, William R Schief
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1011895 (2024)
Carbohydrates and glycoproteins modulate key biological functions. However, experimental structure determination of sugar polymers is notoriously difficult. Computational approaches can aid in carbohydrate structure prediction, structure determinatio
Externí odkaz:
https://doaj.org/article/5de12898393041bbb087434f918ee19f
Autor:
Anindya Roy, Lei Shi, Ashley Chang, Xianchi Dong, Andres Fernandez, John C. Kraft, Jing Li, Viet Q. Le, Rebecca Viazzo Winegar, Gerald Maxwell Cherf, Dean Slocum, P. Daniel Poulson, Garrett E. Casper, Mary L. Vallecillo-Zúniga, Jonard Corpuz Valdoz, Marcos C. Miranda, Hua Bai, Yakov Kipnis, Audrey Olshefsky, Tanu Priya, Lauren Carter, Rashmi Ravichandran, Cameron M. Chow, Max R. Johnson, Suna Cheng, McKaela Smith, Catherine Overed-Sayer, Donna K. Finch, David Lowe, Asim K. Bera, Gustavo Matute-Bello, Timothy P. Birkland, Frank DiMaio, Ganesh Raghu, Jennifer R. Cochran, Lance J. Stewart, Melody G. Campbell, Pam M. Van Ry, Timothy Springer, David Baker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The RGD (Arg-Gly-Asp)-binding integrins αvβ6 and αvβ8 are clinically validated cancer and fibrosis targets of considerable therapeutic importance. Compounds that can discriminate between homologous αvβ6 and αvβ8 and other RGD integri
Externí odkaz:
https://doaj.org/article/e3c311aafe5446188603fdc35eee2511
Autor:
Annie Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael J. Watson, John C. Kraft, Minh N. Pham, Miklos Guttman, Kelly K. Lee, Masaru Kanekiyo, Neil P. King
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113553- (2023)
Summary: The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques to enhance the functional breadth
Externí odkaz:
https://doaj.org/article/3cefb334ae1442beba2b9a737c54329f
Autor:
Annie Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael Watson, John C. Kraft, Minh N. Pham, Miklos Guttman, Kelly K. Lee, Masaru Kanekiyo, Neil P. King
Publikováno v:
bioRxiv
SUMMARYThe head domain of influenza hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies during infection and vaccination. Here we evaluated a series of immunogens that combined several immunofocusing techniques for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125c1b7bbe454c51105c2da3d7034c45
https://europepmc.org/articles/PMC10245820/
https://europepmc.org/articles/PMC10245820/
Akademický článek
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Akademický článek
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Autor:
David C. Kraft, Muhammad Naeem, Joseph Mansour, Michael A. Beal, Thomas C. Bailey, Sanjeev Bhalla
Publikováno v:
RadioGraphics. 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e2f226c44ae8793107cb2392b625c5
https://doi.org/10.1148/rg.220092
https://doi.org/10.1148/rg.220092
Autor:
John C. Kraft, Minh N. Pham, Laila Shehata, Mitch Brinkkemper, Seyhan Boyoglu-Barnum, Kaitlin R. Sprouse, Alexandra C. Walls, Suna Cheng, Mike Murphy, Deleah Pettie, Maggie Ahlrichs, Claire Sydeman, Max Johnson, Alyssa Blackstone, Daniel Ellis, Rashmi Ravichandran, Brooke Fiala, Samuel Wrenn, Marcos Miranda, Kwinten Sliepen, Philip J.M. Brouwer, Aleksandar Antanasijevic, David Veesler, Andrew B. Ward, Masaru Kanekiyo, Marion Pepper, Rogier W. Sanders, Neil P. King
Publikováno v:
Cell Reports Medicine, 3(10):100780. Cell Press
Protein nanoparticle scaffolds are increasingly used in next-generation vaccine designs, and several have established records of clinical safety and efficacy. Yet the rules for how immune responses specific to nanoparticle scaffolds affect the immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4dee6a89727fda946352d9dc45e9a4
https://pure.amc.nl/en/publications/antigen-and-scaffoldspecific-antibody-responses-to-protein-nanoparticle-immunogens(715ac779-3b1c-4879-9a6b-1a3c0e954171).html
https://pure.amc.nl/en/publications/antigen-and-scaffoldspecific-antibody-responses-to-protein-nanoparticle-immunogens(715ac779-3b1c-4879-9a6b-1a3c0e954171).html