Zobrazeno 1 - 10
of 918
pro vyhledávání: '"C. Kraft"'
Publikováno v:
Heliyon, Vol 7, Iss 4, Pp e06714- (2021)
Salmonella spp. remains a wide-spread pathogen among pig herds and its control has major impact on food borne Salmonella infections in humans. The objective of the study was to investigate the influence of an Enterisol® Ileitis vaccination on Salmon
Externí odkaz:
https://doaj.org/article/102e6c261c2e4249b169850df2810957
Autor:
Marcos C. Miranda, Elizabeth Kepl, Mary Jane Navarro, Chengbo Chen, Max Johnson, Kaitlin R. Sprouse, Cameron Stewart, Anne Palser, Adian Valdez, Deleah Pettie, Claire Sydeman, Cassandra Ogohara, John C. Kraft, Minh Pham, Michael Murphy, Sam Wrenn, Brooke Fiala, Rashmi Ravichandran, Daniel Ellis, Lauren Carter, Davide Corti, Paul Kellam, Kelly Lee, Alexandra C. Walls, David Veesler, Neil P. King
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract We previously described a two-component protein nanoparticle vaccine platform that displays 60 copies of the SARS-CoV-2 spike protein RBD (RBD-NP). The vaccine, when adjuvanted with AS03, was shown to elicit robust neutralizing antibody and
Externí odkaz:
https://doaj.org/article/649dcf2c588340c39547078121604655
Autor:
Jared Adolf-Bryfogle, Jason W Labonte, John C Kraft, Maxim Shapovalov, Sebastian Raemisch, Thomas Lütteke, Frank DiMaio, Christopher D Bahl, Jesper Pallesen, Neil P King, Jeffrey J Gray, Daniel W Kulp, William R Schief
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1011895 (2024)
Carbohydrates and glycoproteins modulate key biological functions. However, experimental structure determination of sugar polymers is notoriously difficult. Computational approaches can aid in carbohydrate structure prediction, structure determinatio
Externí odkaz:
https://doaj.org/article/5de12898393041bbb087434f918ee19f
Autor:
Annie Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael J. Watson, John C. Kraft, Minh N. Pham, Miklos Guttman, Kelly K. Lee, Masaru Kanekiyo, Neil P. King
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113553- (2023)
Summary: The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques to enhance the functional breadth
Externí odkaz:
https://doaj.org/article/3cefb334ae1442beba2b9a737c54329f
Autor:
Annie Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael Watson, John C. Kraft, Minh N. Pham, Miklos Guttman, Kelly K. Lee, Masaru Kanekiyo, Neil P. King
Publikováno v:
bioRxiv
SUMMARYThe head domain of influenza hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies during infection and vaccination. Here we evaluated a series of immunogens that combined several immunofocusing techniques for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125c1b7bbe454c51105c2da3d7034c45
https://europepmc.org/articles/PMC10245820/
https://europepmc.org/articles/PMC10245820/
Akademický článek
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Autor:
David C. Kraft, Muhammad Naeem, Joseph Mansour, Michael A. Beal, Thomas C. Bailey, Sanjeev Bhalla
Publikováno v:
RadioGraphics. 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e2f226c44ae8793107cb2392b625c5
https://doi.org/10.1148/rg.220092
https://doi.org/10.1148/rg.220092
Autor:
John C. Kraft, Minh N. Pham, Laila Shehata, Mitch Brinkkemper, Seyhan Boyoglu-Barnum, Kaitlin R. Sprouse, Alexandra C. Walls, Suna Cheng, Mike Murphy, Deleah Pettie, Maggie Ahlrichs, Claire Sydeman, Max Johnson, Alyssa Blackstone, Daniel Ellis, Rashmi Ravichandran, Brooke Fiala, Samuel Wrenn, Marcos Miranda, Kwinten Sliepen, Philip J.M. Brouwer, Aleksandar Antanasijevic, David Veesler, Andrew B. Ward, Masaru Kanekiyo, Marion Pepper, Rogier W. Sanders, Neil P. King
Publikováno v:
Cell Reports Medicine, 3(10):100780. Cell Press
Protein nanoparticle scaffolds are increasingly used in next-generation vaccine designs, and several have established records of clinical safety and efficacy. Yet the rules for how immune responses specific to nanoparticle scaffolds affect the immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4dee6a89727fda946352d9dc45e9a4
https://pure.amc.nl/en/publications/antigen-and-scaffoldspecific-antibody-responses-to-protein-nanoparticle-immunogens(715ac779-3b1c-4879-9a6b-1a3c0e954171).html
https://pure.amc.nl/en/publications/antigen-and-scaffoldspecific-antibody-responses-to-protein-nanoparticle-immunogens(715ac779-3b1c-4879-9a6b-1a3c0e954171).html
Autor:
Morgan M. Sparks, Joshua C. Kraft, Kliffi M. Subida Blackstone, Gordon G. McNickle, Mark R. Christie
Publikováno v:
Proceedings of the Royal Society B: Biological Sciences. 289
Environmentally covarying local adaptation is a form of cryptic local adaptation in which the covariance of the genetic and environmental effects on a phenotype obscures the divergence between locally adapted genotypes. Here, we systematically docume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5be8efbd17efa6eb9c5d68dcb4070d
https://doi.org/10.1098/rspb.2022.1472
https://doi.org/10.1098/rspb.2022.1472
Autor:
Jason Z. Zhang, Hsien-Wei Yeh, Alexandra C. Walls, Basile I. M. Wicky, Kaitlin R. Sprouse, Laura A. VanBlargan, Rebecca Treger, Alfredo Quijano-Rubio, Minh N. Pham, John C. Kraft, Ian C. Haydon, Wei Yang, Michelle DeWitt, John E. Bowen, Cameron M. Chow, Lauren Carter, Rashmi Ravichandran, Mark H. Wener, Lance Stewart, David Veesler, Michael S. Diamond, Alexander L. Greninger, David M. Koelle, David Baker
Publikováno v:
Nature biotechnology, vol 40, iss 9
We designed a protein biosensor that uses thermodynamic coupling for sensitive and rapid detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in serum. The biosensor is a switchable, caged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458cd9dfec1e4f5632dd9fdbf5b270ba
https://escholarship.org/uc/item/1b11v74r
https://escholarship.org/uc/item/1b11v74r