Zobrazeno 1 - 10
of 116
pro vyhledávání: '"C. Kirchberger"'
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Microviruses encompass an astonishing array of small, single-stranded DNA phages that, due to the surge in metagenomic surveys, are now known to be prevalent in most environments. Current taxonomy concedes the considerable diversity within t
Externí odkaz:
https://doaj.org/article/8de1aac521c849d6b97f1772b0630755
Autor:
Libuše Janská, Libi Anandi, Nell C. Kirchberger, Zoran S. Marinkovic, Logan T. Schachtner, Gizem Guzelsoy, Carlos Carmona-Fontaine
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
There is an urgent need for accurate, scalable and cost-efficient models of the tumor microenvironment. Here, we detail how to fabricate and use the metabolic microenvironment chamber (MEMIC) – a 3D-printed ex vivo model of intratumoral heterogenei
Externí odkaz:
https://doaj.org/article/1cedd57074184b5d984999b8e368a9e5
Autor:
Markus V. Heppt, Teresa Amaral, Katharina C. Kähler, Lucie Heinzerling, Jessica C. Hassel, Markus Meissner, Nicole Kreuzberg, Carmen Loquai, Lydia Reinhardt, Jochen Utikal, Evelyn Dabrowski, Anja Gesierich, Claudia Pföhler, Patrick Terheyden, Kai-Martin Thoms, Lisa Zimmer, Thomas K. Eigentler, Michael C. Kirchberger, Henner M. Stege, Friedegund Meier, Max Schlaak, Carola Berking
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Uveal melanoma (UM) is highly refractory to treatment with dismal prognosis in advanced stages. The value of the combined checkpoint blockade with CTLA-4 and PD-1 inhibition in metastatic UM is currently unclear. Methods Patients
Externí odkaz:
https://doaj.org/article/39e18ef3acc940829b41d0958141f699
Autor:
Theresa Steeb, Anja Wessely, Heike Merkl, Michael C. Kirchberger, Caroline Voskens, Michael Erdmann, Lucie Heinzerling, Carola Berking, Markus V. Heppt
Publikováno v:
Acta Dermato-Venereologica, Vol 101, Iss 6, p adv00482 (2021)
An important measure of hospital quality is the satisfaction of patients. The aim of this cross-sectional study, performed in the dermato-oncology unit of the university hospital in Erlangen, Germany, was to assess skin cancer patients’ degree of s
Externí odkaz:
https://doaj.org/article/4235e391fd95414fa60de17709833e62
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The type VI secretion system (T6SS) operons of Vibrio cholerae contain extraordinarily diverse arrays of toxic effector and cognate immunity genes, which are thought to play an important role in the environmental lifestyle and adaptation of this huma
Externí odkaz:
https://doaj.org/article/dedbec7ed5e0450ebbbb0125e23ab7b4
Autor:
Anju Nohria, Alexander R Lyon, Stephane Ederhy, Franck Thuny, Michael Mahmoudi, Magid Awadalla, Dahlia Banerji, Merna Armanious, Dipti Gupta, Sarju Ganatra, Paaladinesh Thavendiranathan, Gagan Sahni, Ryan Sullivan, Lili Zhang, Tomas G Neilan, Daniel A Zlotoff, Malek Z O Hassan, Amna Zafar, Raza M Alvi, Syed S Mahmood, Carol L Chen, Ana Barac, Maeve Jones-O'Connor, Sean P Murphy, Brian J Forrestal, Michael C Kirchberger, Otavio R Coelho-Filho, Muhammad A Rizvi, Anant Mandawat, Carlo G Tocchetti, Sarah Hartmann, Hannah K Gilman, Eduardo Zatarain-Nicolás, Lucie M Heinzerling, Justine V Cohen, John Groarke, Michael G Fradley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Myocarditis is a highly morbid complication of immune checkpoint inhibitor (ICI) use that remains inadequately characterized. The QRS duration and the QTc interval are standardized electrocardiographic measures that are prolonged in other
Externí odkaz:
https://doaj.org/article/e0d49c053cc347dfa4d4fbdd78de84e0
Autor:
Paul C Kirchberger, Howard Ochman
Publikováno v:
eLife, Vol 9 (2020)
Gokushoviruses are single-stranded, circular DNA bacteriophages found in metagenomic datasets from diverse ecosystems worldwide, including human gut microbiomes. Despite their ubiquity and abundance, little is known about their biology or host range:
Externí odkaz:
https://doaj.org/article/b7f2e1041a13404daf2c7d0fd10ae88d
Autor:
Justine V. Cohen, Doll Lauren Alexandra Golden, Syed S. Mahmood, Raza M. Alvi, Nathaniel D. Mercaldo, Malek Z. O. Hassan, Adam Rokicki, Connor Mulligan, Sean P. T. Murphy, Maeve Jones-O’Connor, Lucie M. Heinzerling, Rongras Damrongwatanasuk, Carol L. Chen, Michael C. Kirchberger, Sachin P. Shah, Muhammad A. Rizvi, Carlo G. Tocchetti, Valentina Mercurio, Donald P. Lawrence, John D. Groarke, Michael G. Fradley, Kerry L. Reynolds, Tomas G. Neilan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
BackgroundInfluenza vaccination (FV) is recommended for patients with cancer. Recent data suggested that the administration of the FV was associated with an increase in immune-related adverse events (irAEs) among patients on immune checkpoint inhibit
Externí odkaz:
https://doaj.org/article/23d13b13f69045c4aed81f89294aab8e
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Autor:
Tania Nasreen, Nora A. S. Hussain, Mohammad Tarequl Islam, Fabini D. Orata, Paul C. Kirchberger, Rebecca J. Case, Munirul Alam, Stephanie K. Yanow, Yann F. Boucher
Publikováno v:
Pathogens, Vol 9, Iss 12, p 1053 (2020)
Vibrio metoecus is a recently described aquatic bacterium and opportunistic pathogen, closely related to and often coexisting with Vibrio cholerae. To study the relative abundance and population dynamics of both species in aquatic environments of cho
Externí odkaz:
https://doaj.org/article/4beac85abe30490fa79c0b6ee34bb352