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Embryonic Stem Cells Generate Airway Epithelial Tissue

Autor: Dominique Gaillard, Edith Puchelle, Christian Dani, Christelle Coraux, Béatrice Nawrocki-Raby, Jocelyne Hinnrasky, C. Kileztky

Publikováno v: American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2005, 32 (2), pp.87-92. ⟨10.1165/rcmb.2004-0079RC⟩

Embryonic stem (ES) cells are self-renewable and pluripotent cells derived from the inner cell mass of a blastocyst-stage embryo. ES cell pluripotency is being investigated increasingly to obtain specific cell lineages for therapeutic treatments and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1327e79ad15c621539c21949c6be4eb1
https://doi.org/10.1165/rcmb.2004-0079rc

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Airway Epithelial Integrity Is Protected by a Long-Acting β2-Adrenergic Receptor Agonist

Autor: Edith Puchelle, Jocelyne Hinnrasky, Christelle Coraux, Philippe Devillier, Jean-Marie Zahm, Sophie de Bentzmann, C. Kileztky, Myriam Polette

Publikováno v: American Journal of Respiratory Cell and Molecular Biology
American Journal of Respiratory Cell and Molecular Biology, American Thoracic Society, 2004, 30 (5), pp.605-12. ⟨10.1165/rcmb.2003-0056OC⟩
American Journal of Respiratory Cell and Molecular Biology, 2004, 30 (5), pp.605-12. ⟨10.1165/rcmb.2003-0056OC⟩

Airway epithelial integrity may be impaired by bacterial exoproducts, which are able to degrade tight junction-associated proteins such as zonula occludens 1 (ZO-1). We have investigated the protective effect of salmeterol, a long-acting beta(2)-adre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6de77a6da4e1e9a3c8cd68346239a2f
https://doi.org/10.1165/rcmb.2003-0056oc

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Long acting β2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant

Autor: Jean-Marie Zahm, C. Kileztky, Malcolm Johnson, Christelle Coraux, Gérard Balossier, Béatrice Nawrocki-Raby, Philippe Birembaut, Jean Michel, Férial Toumi, Franck Delavoie

Publikováno v: Respiratory Research
Respiratory Research, BioMed Central, 2010, 11 (1), pp.6. ⟨10.1186/1465-9921-11-6⟩
Respiratory Research, 2010, 11 (1), pp.6. ⟨10.1186/1465-9921-11-6⟩
Respiratory Research, Vol 11, Iss 1, p 6 (2010)

Background: Staphylococcus aureus releases virulence factors (VF) that may impair the innate protective functions of airway cells. The aim of this study was to determine whether a long-acting b2 adrenergic receptor agonist (salmeterol hydroxynaphthoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a63c3cf7915dcb775a716835639b0e8
https://www.hal.inserm.fr/inserm-00663538/file/1465-9921-11-6.pdf

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Downregulation by a long-acting beta2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial inflammatory mediator production

Autor: Malcolm Johnson, Edith Puchelle, C. Kileztky, Chantal Trentesaux, Odile Bajolet, Konstantina Fragaki, Jean-Marie Zahm

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2006, 291 (1), pp.L11-8. ⟨10.1152/ajplung.00488.2005⟩

Although Staphylococcus aureus is a major cause of pulmonary infection, the role played by this bacterium in the induction of inflammation of human airway epithelial cells (HAEC) is poorly understood. In this study, we investigated the inflammatory r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb638ce6e42a1e1f36d10548cedd6ca9
https://www.hal.inserm.fr/inserm-00143592

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Pseudomonas aeruginosa virulence factors delay airway epithelial wound repair by altering the actin cytoskeleton and inducing overactivation of epithelial matrix metalloproteinase-2

Autor: Alain Filloux, C. Kileztky, Odile Bajolet, S. de Bentzmann, Jocelyne Hinnrasky, E. Puchelle, Jean-Michel Klossek, Myriam Polette, Andrée Lazdunski, J.M. Zahm

Publikováno v: Laboratory investigation; a journal of technical methods and pathology. 80(2)

To investigate the role of P. aeruginosa virulence factors in the repair of human airway epithelial cells (HAEC) in culture, we evaluated the effect of stationary-phase supernatants from the wild-type strain PAO1 on cell migration, actin cytoskeleton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7665808f037cb7bc18c73ef209479a4
https://pubmed.ncbi.nlm.nih.gov/10701690

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010 Effet anti-inflammatoire de l’association d’un agoniste des récepteurs β2-adrenergiques et d’un corticostéroïde sur les cellules épithéliales bronchiques humaines après l’infection par Staphylococcus aureus

Autor: C. Kileztky, J.M. Zahm, E. Puchelle, Konstantina Fragaki

Publikováno v: Revue des Maladies Respiratoires. 22:848

Introduction L’epithelium respiratoire represente la premiere ligne de defense vis-a-vis des agents pathogenes tels que S. aureus . L’objectif de ce travail a ete l’analyse de l’effet anti-inflammatoire de l’association d’un agoniste des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8a918339e140de48d05d82854b30b68
https://doi.org/10.1016/s0761-8425(05)92422-4

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015 Les sphéroïdes bronchiques: un modèle d’étude des cellules épithélialesbronchiques au cours des BPCO

Autor: Gaëtan Deslée, Konstantina Fragaki, Jocelyne Hinnrasky, E. Puchelle, Sandra Dury, F. Vitry, François Lebargy, C. Kileztky, V. Garcia

Publikováno v: Revue des Maladies Respiratoires. 22:850

Introduction Les cellules epitheliales bronchiques (CEB) secretent differents mediateurs inflammatoires impliques dans la physio-pathologie des BPCO. L’objectif de ce travail est d’etudier les specificites des CEB au cours des BPCO au moyen d’u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1193dad8d4d5b808b31e3c91acbf3d3
https://doi.org/10.1016/s0761-8425(05)92427-3

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