Výsledky vyhledávání - "C. K. Acosta"

A practical large-scale synthesis of 17α-acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914)

Autor: Pemmaraju N. Rao, C. K. Acosta, James W. Cessac, James E. Burdett, P A Morrison, M. L. Bahr, Hyun K. Kim

Publikováno v: Steroids. 65:395-400

A new practical synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914) is described. The synthesis gives easily isolable solids at all steps and is amenable to large-scale process.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6bcd8bbb9311ef158e2cdb1af23990
https://doi.org/10.1016/s0039-128x(00)00100-8

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Synthesis of N-desmethyl derivatives of 17α-acetoxy-11β- (4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione and mifepristone1 Substrates for the synthesis of radioligands

Autor: Pemmaraju N. Rao, M. L. Bahr, James W. Cessac, C. K. Acosta, Hyun K. Kim

Publikováno v: Steroids. 64:205-212

The syntheses of N-desmethyl derivatives of CDB-2914 and the mono-N-desmethyl derivative of Mifepristone are described. We also describe the use of the mono-desmethyl derivatives as substrates for the synthesis of N-tritomethyl derivatives of CDB-291

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d4ec0f1ef4bfa124429b1f27f87135
https://doi.org/10.1016/s0039-128x(98)00086-5

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ChemInform Abstract: Synthesis of cis- and trans-4-Aminocyclohexyl-D-alanine Derivatives and Determination of Their Stereochemistry

Autor: M. L. Bahr, Dorothy M. Peterson, Hyun K. Kim, C. K. Acosta, Pemmaraju N. Rao

Publikováno v: ChemInform. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd685671761cfb2205c9933e9d478265
https://doi.org/10.1002/chin.199145265

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ChemInform Abstract: Synthesis of Unnatural Amino Acids

Autor: Hyun K. Kim, Rodolfo A. Martinez, M. L. Bahr, C. K. Acosta, Pemmaraju N. Rao, James W. Cessac, J. E. Jun. Burdett

Publikováno v: ChemInform. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4233426b11c79aec70e808bcdb50ea9c
https://doi.org/10.1002/chin.199133264

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Tritium labeled trans-4-n-butyl-2,3-3H-cyclohexanecarboxylic acid. Preparation of testosterone 17β-trans-4-n-butyl-2,3-3H-cyclohexanecarboxylate and [4-14C]-testosterone 17β-trans-4-n-butylcyclohexane carboxylate

Autor: Pemmaraju N. Rao, C. K. Acosta, Hyun K. Kim, James W. Cessac

Publikováno v: Journal of Labelled Compounds and Radiopharmaceuticals. 28:1201-1212

The synthesis of trans-4-n-butyl-2,3-3H-cyclohexanecarboxylic acid is described. The title compound was synthesized by catalytic tritiation of 4-n-butylcyclohex-2-enecarboxylic acid, which was obtained from a “double” Birch reduction of 4-n-butyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edfd3477b7a30ae714b702b4c986f901
https://doi.org/10.1002/jlcr.2580281013

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