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pro vyhledávání: '"C. Jenny Mu"'
Autor:
C. Jenny Mu, Justin P. Edwards, Haiying Qin, David M. Hilbert, David W. Lafleur, Terry J. Fry, Ankit Gupta, Liubov Zaritskaya
Publikováno v:
Mol Ther
Chimeric antigen receptor (CAR) T cell therapies have demonstrated impressive initial response rates in hematologic malignancies. However, relapse rates are significant, and robust efficacies in other indications, such as solid tumors, will likely re
Autor:
Terry J. Fry, Haiying Qin, David W. Lafleur, C. Jenny Mu, Laura K. Richman, Justin P. Edwards, Ankit Gupta, David M. Hilbert, Liubov Zaritskaya
Publikováno v:
Cancer Research. 80:601-601
Unlike the tumor targets associated with initial CAR T cell successes, the vast majority of tumor associated antigens are not unique, but rather expressed at elevated levels compared to normal tissue. For example, while CD123 is overexpressed on many
Publikováno v:
ACS Nano. 4:1511-1520
Target-activatable fluorogenic probes based on gold nanoparticles (AuNPs) functionalized with self-assembled heterogeneous monolayers of dye-labeled peptides and poly(ethylene glycol) have been developed to visualize proteolytic activity in vivo. A o