Zobrazeno 1 - 10
of 220
pro vyhledávání: '"C. J. Thiele"'
Publikováno v:
Cell Death & Differentiation. 10:230-239
Poor prognosis neuroblastoma (NB) tumors are marked by amplification and overexpression of N-myc. Retinoic acid (RA) decreases N-myc levels and induces cell cycle arrest in vitro and increases event-free survival in advanced stage NB patients. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b496e0ef080d800124eaea3e847fd4
https://doi.org/10.1038/sj.cdd.4401125
https://doi.org/10.1038/sj.cdd.4401125
Publikováno v:
The Journal of biological chemistry. 275(22)
The human unc-33-like phosphoprotein (hUlip/CRMP-4) is a member of a family of developmentally regulated genes that are highly expressed in the nervous system. Mutations in the C. elegans unc-33 gene lead to worms with abnormal movements. The hUlip g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a395a1e7fa0a383ed581cf1724956a96
https://pubmed.ncbi.nlm.nih.gov/10748015
https://pubmed.ncbi.nlm.nih.gov/10748015
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 79(8)
Expression level of trkA tyrosine kinase receptor for nerve growth factor is a major prognostic determinant of neuroblastoma, suggesting that defective trkA-mediated signaling is responsible for the tumorigenesis of this childhood malignancy. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f427edaef7299c3f26e0f97971850fd
https://pubmed.ncbi.nlm.nih.gov/10462038
https://pubmed.ncbi.nlm.nih.gov/10462038
Autor:
L A, Goodman, B C, Liu, C J, Thiele, M L, Schmidt, S L, Cohn, J M, Yamashiro, D S, Pai, N, Ikegaki, R K, Wada
Publikováno v:
Clinicalexperimental metastasis. 15(2)
N-myc oncogene expression plays a pivotal role in the biology of neuroblastoma, a common childhood tumor. High N-myc expression is associated with advanced disease stage, and in animal models, increased expression results in increased metastatic pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::326d41d718e982241438ed6eab5ec786
https://pubmed.ncbi.nlm.nih.gov/9062389
https://pubmed.ncbi.nlm.nih.gov/9062389
Publikováno v:
Journal of neuro-oncology. 31(1-2)
Cell proliferation, the balance between mitosis and apoptosis is the result of the continuous integration of a number of different signal transduction pathways stimulated in a cell at any given point in its life. Neuroblastoma cells regulate the swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91a50e9be1ddf2af42f0925af9d31103
https://pubmed.ncbi.nlm.nih.gov/9049832
https://pubmed.ncbi.nlm.nih.gov/9049832
Publikováno v:
Cancer research. 55(11)
Recent work on a variety of normal and malignant cell lines has shown that induction and secretion of biologically active TGF-beta may occur after exposure to all-trans-retinoic acid (RA), coincident with decreased growth rate and/or differentiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a74dfc0d0ba28f17cd268119a970e325
https://pubmed.ncbi.nlm.nih.gov/7757990
https://pubmed.ncbi.nlm.nih.gov/7757990
Autor:
Y.-H. Kubota, C. J. Thiele, Balboni Gc, Tullio Barni, Giovanni G. Camici, A. Becchetti, F. Ensoli, Gabriella B. Vannelli, R. Zonefrati, Annarosa Arcangeli
Publikováno v:
Scopus-Elsevier
Primary cell cultures from human fetal olfactory neuroepithelium have been isolated, cloned, and propagated in continuous in vitro culture for approximately 1 year. The two clones we report here synthesize both neuronal proteins and olfactory-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8665996c1097e32cb3fb97d3dc2c6612
https://europepmc.org/articles/PMC6577713/
https://europepmc.org/articles/PMC6577713/
Publikováno v:
Cancer research. 55(8)
A large number of poor prognosis neuroblastoma (NB) tumors constitutively express brain-derived neurotrophic factor (BDNF) and variably express the gene for its tyrosine kinase (Trk) receptor TrkB. Good prognosis NB tumors typically express high leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a03ba1252df3e0c46f5707d1a5820c74
https://pubmed.ncbi.nlm.nih.gov/7712490
https://pubmed.ncbi.nlm.nih.gov/7712490
Autor:
C J, Thiele, G, Melino
Publikováno v:
Cell death and differentiation. 1(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88e21a81c8b8938f3410313fbea3442f
https://pubmed.ncbi.nlm.nih.gov/17334329
https://pubmed.ncbi.nlm.nih.gov/17334329
Publikováno v:
Cell death and differentiation. 1(1)
Retinoic Acid (RA) has been shown to control growth and induce differentiation in a number of human neuroblastoma (NB) cell lines. However, a number of NB cell lines may be termed resistant to RA as they fail to growth arrest and differentiate. In st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43821269d820723bd3d90da3609f296c
https://pubmed.ncbi.nlm.nih.gov/17180006
https://pubmed.ncbi.nlm.nih.gov/17180006