Výsledky vyhledávání - "C. J. Petropoulos"

Manufacture of Proteins Based on Recombinant Chinese Hamster Ovary Cells: Assessment of Genetic Issues and Assurance of Consistency and Quality

Autor: J. V. O’Connor, C. J. Petropoulos, F. M. Wurm

Publikováno v: Transgenic Organisms and Biosafety ISBN: 9783540610779

Chinese Hamster Ovary (CHO) cells are a popular mammalian host for the production of complex proteins for clinical applications. Today, more than 60% of candidate proteins for therapeutic and prophylactic purposes are being produced in mammalian cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a2bfbc8e32256b0781953641034c6d3
https://doi.org/10.1007/978-3-642-61460-6_28

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Expression and role of c-myc in chondrocytes undergoing endochondral ossification

Autor: M, Iwamoto, K, Yagami, P, Lu Valle, B R, Olsen, C J, Petropoulos, D L, Ewert, M, Pacifici

Publikováno v: The Journal of biological chemistry. 268(13)

To analyze the relationship between c-myc gene expression and chondrocyte proliferation and maturation during endochondral ossification, Day 18-19 chick embryo sterna were pulse-labeled with [3H]thymidine, and serial sections were processed for autor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd62cf6fc5a959bb4323fb2e6b782b6c
https://pubmed.ncbi.nlm.nih.gov/8486652

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Appropriate in vivo expression of a muscle-specific promoter by using avian retroviral vectors for gene transfer [corrected]

Autor: William S. Payne, Donald W. Salter, Stephen H. Hughes, C J Petropoulos

Publikováno v: Journal of virology. 66(6)

The promoter regions of the chicken skeletal muscle alpha-actin (alpha sk-actin) and the cytoplasmic beta-actin genes were linked to the bacterial chloramphenicol acetyltransferase (CAT) gene. Replication-competent retroviral vectors were used to int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02759366b935582c7c35c85469811d55
https://pubmed.ncbi.nlm.nih.gov/1637416

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Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors

Autor: S H Hughes, C J Petropoulos, P Sutrave, J J Greenhouse

Publikováno v: Journal of Virology. 61:3004-3012

We have previously described several helper independent vector constructions (S. Hughes and E. Kosik, Virology 136:89-99, 1984; J. Sorge and S. H. Hughes, J. Mol. Appl. Genet. 1:547-599, 1982; J. Sorge, B. Ricci, and S. Hughes, J. Virol. 48:667-675,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d332e3f9196a13bd8344a124ef8b7f
https://doi.org/10.1128/jvi.61.10.3004-3012.1987

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The chicken skeletal muscle alpha-actin promoter is tissue specific in transgenic mice

Autor: Nancy A. Jenkins, S. H. Hughes, Michael P. Rosenberg, Neal G. Copeland, C. J. Petropoulos

Publikováno v: Molecular and Cellular Biology. 9:3785-3792

We have generated transgenic mouse lines that carry the promoter region of the chicken skeletal muscle alpha (alpha sk) actin gene linked to the bacterial chloramphenicol acetyltransferase (CAT) gene. In adult mice, the pattern of transgene expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::977c0b8e8c59771ac49ae057bf94ba28
https://doi.org/10.1128/mcb.9.9.3785

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Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver

Autor: P R Shank, C J Petropoulos, Michele Goyette, Nelson Fausto

We examined the transcription of six cellular oncogenes during the process of compensatory growth in rat liver after partial hepatectomy. We have previously reported that transcripts of c-rasH are elevated during regenerative growth of the liver. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4df4edbbe9561c235235daa1b2b27c
https://europepmc.org/articles/PMC368939/

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Cell lineages in liver carcinogenesis: possible clues from studies of the distribution of alpha-fetoprotein RNA sequences in cell populations isolated from normal, regenerating, and preneoplastic rat livers

Autor: C J, Petropoulos, P, Yaswen, M, Panzica, N, Fausto

Publikováno v: Cancer research. 45(11 Pt 2)

We analyzed in isolated rat liver cell populations and in fetal and neoplastic livers the distribution of RNA sequences which hybridize with alpha-fetoprotein (AFP) complementary DNA clones. Parenchymal and nonparenchymal cell populations were isolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6577d7e150572c9f7a5187828cdc6c68
https://pubmed.ncbi.nlm.nih.gov/2413996

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Homology between rat liver RNA populations during development, regeneration, and neoplasia

Autor: C J, Petropoulos, J M, Lemire, D, Goldman, N, Fausto

Publikováno v: Cancer research. 45(10)

To investigate the degree of homology which may exist between rat liver RNA populations during development, regeneration, and neoplasia, we hybridized polyadenylated RNAs from (a) normal adult, (b) 24-h regenerating, (c) 20-day fetal livers, and (d)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7261afa9c7f0f8c90e458e602e8cf6fd
https://pubmed.ncbi.nlm.nih.gov/2411393

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