Zobrazeno 1 - 10
of 25
pro vyhledávání: '"C. J. PARLI"'
Publikováno v:
Toxicological Sciences. 19:197-201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b517cda813d793ce75077762b924277
https://doi.org/10.1093/toxsci/19.2.197
https://doi.org/10.1093/toxsci/19.2.197
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(2)
Recently discovered serotonin3 (5-HT3) receptor antagonists are potent antiemetics in cytotoxic drug-induced vomiting. The specific site where 5-HT3 receptor antagonists act to abolish emesis is controversial. The major objective of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0e2513d8d4c21ef612969ce3ed59725
https://pubmed.ncbi.nlm.nih.gov/7752072
https://pubmed.ncbi.nlm.nih.gov/7752072
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 22(3)
The major in vivo human metabolite of zatosetron is 8-alpha-methyl,8-beta-oxo zatosetron [N-O (1) zatosetron]. N-Desmethyl zatosetron (NdM zatosetron) and 3-hydroxy-zatosetron (3-OH-zatosetron) are minor human metabolites. In the rat, the primary in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1488152f9e820a0950411024ec10346d
https://pubmed.ncbi.nlm.nih.gov/8070310
https://pubmed.ncbi.nlm.nih.gov/8070310
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 19(2)
Studies were undertaken to define the subchronic toxicologic profile of ameltolide, an aminobenzamide anticonvulsant, in young adult rhesus monkeys. Daily doses of ameltolide, dissolved in 10% aqueous acacia, were administered orally via nasogastric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432a9aff10838b6b350332ddaba84e36
https://pubmed.ncbi.nlm.nih.gov/1516775
https://pubmed.ncbi.nlm.nih.gov/1516775
Autor:
R A, Hahn, B R, MacDonald, E, Morgan, B D, Potts, C J, Parli, L E, Rinkema, C A, Whitesitt, W S, Marshall
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(3)
In vitro studies have shown LY203647 to be a selective antagonist of contractile responses to leukotriene (LT) D4 and LTE4 in guinea pig ileum, trachea and lung parenchyma. In pithed rat, i.v. injection of LTD4 produced pressor responses that were se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45cffe9c0184d6ecc8bbb6f352affe2a
https://pubmed.ncbi.nlm.nih.gov/1312172
https://pubmed.ncbi.nlm.nih.gov/1312172
Autor:
M M, Foreman, R W, Fuller, D L, Nelson, D O, Calligaro, K D, Kurz, J W, Misner, W L, Garbrecht, C J, Parli
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(1)
8B-N-cyclohexyl-6-methyl-1(1-methylethyl)ergoline-8-carboxamide (LY237733) is an ergoline with potent and highly selective 5-hydroxytryptamine (5-HT) antagonist activity. The in vitro radioligand displacement studies showed that LY237733 has a prefer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94ccfe4be6934aa995a7b8b516776f5f
https://pubmed.ncbi.nlm.nih.gov/1731051
https://pubmed.ncbi.nlm.nih.gov/1731051
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 253(1)
Injection of leukotriene (LT)B4 (0.1-3 micrograms/kg i.v.) in normal anesthetized dogs produced dose-related leukopenia that was accompanied by arterial hypotension and tachycardia at higher tested doses. LTD4 (0.1-3 micrograms/kg i.v.), in contrast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a156e82716785ac35b340b2e6ff6e492
https://pubmed.ncbi.nlm.nih.gov/2158553
https://pubmed.ncbi.nlm.nih.gov/2158553
Publikováno v:
ACS Symposium Series ISBN: 9780841217409
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d06c3c8d79a32258bf98da496789518
https://doi.org/10.1021/bk-1990-0420.ch012
https://doi.org/10.1021/bk-1990-0420.ch012
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 251(3)
The ergoline esters, LY53857 [6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid 2-hydroxy-1-methylpropylester (Z)-2-butenedioate] and sergolexole (LY281067) ([trans-(8 beta)]6-methyl-1-[1-methylethyl]ergoline-8-carboxylic acid, 4-methoxycyclohexyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c4cc3c567dceb4a1864ee9a9e1f001e
https://pubmed.ncbi.nlm.nih.gov/2600800
https://pubmed.ncbi.nlm.nih.gov/2600800
Autor:
C J, Parli
Publikováno v:
Psychopharmacology bulletin. 12(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8ae8861ada32cfacd59b3ea92b68b76
https://pubmed.ncbi.nlm.nih.gov/959472
https://pubmed.ncbi.nlm.nih.gov/959472