Zobrazeno 1 - 10
of 51
pro vyhledávání: '"C. J. Michejda"'
Publikováno v:
Photochemistry and photobiology. 70(4)
Bisimidazoacridones (BIA) are highly selective antineoplastic and antiviral agents. Ultraviolet-visible spectroscopy and steady-state and time-resolved fluorescence spectroscopy studies were carried out to probe the behavior of BIA in aqueous and non
Autor:
N I, Tarasova, G, Czerwinski, N B, Roberts, J, Lubkowski, T L, Sumpter, B N, Green, C J, Michejda
Publikováno v:
Advances in experimental medicine and biology. 436
Autor:
B. N. Green, C. J. Michejda, G. Czerwinski, Norman B. Roberts, J. Lubkowski, N. I. Tarasova, T. L. Sumpter
Publikováno v:
Aspartic Proteinases ISBN: 9781461374527
In the late eighties, two novel mass spectrometric methods with the sensitivity in the femtomole range were introduced, electrospray mass spectrometry (ESMS) and matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1e4ea9323758209e4f866410f48a1a4
https://doi.org/10.1007/978-1-4615-5373-1_28
https://doi.org/10.1007/978-1-4615-5373-1_28
Publikováno v:
Cancer research. 55(11)
Antitumor bisimidazoacridones are bifunctional DNA binders which have recently been shown to selectively target human colon carcinoma cells in vitro and in vivo and appear to be excellent candidates for clinical development. We have studied the mecha
Autor:
C J, Michejda, M B, Kroeger Koepke
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 27
The foregoing pages presented a substantial body of data that established that sulfotransferase conjugation can transform many xenobiotics into agents that can modify cellular macromolecules. However, activation by sulfation is rarely the only metabo
Publikováno v:
IARC scientific publications. (125)
Publikováno v:
Cancer research. 52(12)
N-Nitrosomethyl(2-hydroxyethyl)amine (NMHEA), when administered by gavage, is a strong liver carcinogen in F344 female rats, but a weak liver carcinogen in male rats. After repeated exposure to NMHEA, either in drinking water or by gavage, female rat
Autor:
C J, Michejda
Publikováno v:
Contributions to gynecology and obstetrics. 18
Publikováno v:
IARC scientific publications. (105)
N-Nitroso-N-methylaniline (NMA) is a strong oesophageal carcinogen in rats but exhibits few overt genotoxic effects. Previous work from our laboratory established that NMA is readily metabolized by cytochrome P450-catalysed N-demethylation to produce