Výsledky vyhledávání - "C. J. Greenbaum"

Intra-islet insulin permits glucose to directly suppress pancreatic A cell function

Autor: Peter J. Havel, Leslie J. Klaff, Gerald J. Taborsky, C. J. Greenbaum

Publikováno v: Greenbaum, CJ; Havel, PJ; Taborsky, GJ; & Klaff, LJ. (1991). Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.. The Journal of clinical investigation, 88(3), 767-773. doi: 10.1172/jci115375. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2sg4377x
The Journal of clinical investigation, vol 88, iss 3

Inhibition of pancreatic glucagon secretion during hyperglycemia could be mediated by (a) glucose, (b) insulin, (c) somatostatin, or (d) glucose in conjunction with insulin. To determine the role of these factors in the mediation of glucagon suppress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f290a47998620f611983540807c4e77
https://doi.org/10.1172/jci115375

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Insulin Antibodies and Insulin Autoantibodies

Autor: C. J. Greenbaum, Jerry P. Palmer

Publikováno v: Diabetic Medicine. 8:97-105

Antibodies to insulin are of two types, insulin antibodies which occur in patients who have been exposed to exogenous insulin treatment, and insulin autoantibodies which appear in insulin-naive subjects. The occurrence and clinical significance of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1476fff8525e8bfd2a8309085e321da8
https://doi.org/10.1111/j.1464-5491.1991.tb01553.x

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Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study

Autor: D. K. McCulloch, L. J. Klaff, S. E. Kahn, S. L. Schoenfeld, C. J. Greenbaum, R. S. Mauseth, E. A. Benson, G. T. Nepom, L. Shewey, J. P. Palmer

Publikováno v: Diabetes. 39:549-556

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::baa869f2fc2d1b9947ce408a2cd3e914
https://doi.org/10.2337/diabetes.39.5.549

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Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope

Autor: D G, Alleva, R A, Maki, A L, Putnam, J M, Robinson, M S, Kipnes, P, Dandona, J B, Marks, D L, Simmons, C J, Greenbaum, R G, Jimenez, P J, Conlon, P A, Gottlieb

Publikováno v: Scandinavian journal of immunology. 63(1)

NBI-6024 is an altered peptide ligand (APL) corresponding to the 9-23 amino acid region of the insulin B chain (B(9-23)), an epitope recognized by inflammatory interferon-gamma-producing T helper (Th)1 lymphocytes in type 1 diabetic patients. Immunom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da9ac9612f7436ed2262c814bfa8e675
https://pubmed.ncbi.nlm.nih.gov/16398702

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Macrophages from high-risk HLA-DQB1*0201/*0302 type 1 diabetes mellitus patients are hypersensitive to lipopolysaccharide stimulation

Autor: A, Plesner, C J, Greenbaum, L K, Gaur, R K, Ernst, A, Lernmark

Publikováno v: Scandinavian journal of immunology. 56(5)

Levels of nonantigen-induced pro-inflammatory cytokines and prostaglandin in macrophages isolated from human leucocyte antigen (HLA)-matched type 1 diabetes mellitus patients, first-degree relatives and healthy controls were determined. We hypothesiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87c169973a252c33007cc00754e3bd2e
https://pubmed.ncbi.nlm.nih.gov/12410803

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Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria

Autor: C J, Greenbaum, D, Cuthbertson, J P, Krischer

Publikováno v: Diabetes. 50(2)

The clinical presentation of type 1 diabetes usually involves symptoms such as polyuria and polydipsia. However, investigators in the Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) have detected a group of subjects with type 1 diabetes who have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d61bd7a7b374462f557bf70830ef4a29
https://pubmed.ncbi.nlm.nih.gov/11272162

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Islet cell antibody-positive relatives with human leukocyte antigen DQA1*0102, DQB1*0602: identification by the Diabetes Prevention Trial-type 1

Autor: C J, Greenbaum, D A, Schatz, D, Cuthbertson, A, Zeidler, G S, Eisenbarth, J P, Krischer

Publikováno v: The Journal of clinical endocrinology and metabolism. 85(3)

The presence of human leukocyte antigen (HLA) haplotype DQA1*0102, DQB1*0602 is associated with protection from type 1 diabetes. The Diabetes Prevention Trial-type 1 has identified 100 islet cell antibody (ICA)-positive relatives with this protective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71e51c3bee62763eb240cbbec2fea0bc
https://pubmed.ncbi.nlm.nih.gov/10720072

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Short-term responses to periodontal therapy in insulin-dependent diabetic patients

Autor: B D Johnson, C J Greenbaum, G R Persson, Gregory T. Smith

Publikováno v: Journal of periodontology. 67(8)

This investigation studied relative changes in periodontal conditions of 18 insulin-dependent diabetic patients. Measures of gingival inflammation, crevicular fluid aspartate aminotransferase (AST) levels, probing depth and attachment levels, the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6573dd89a3e2c507d406aeff954a743d
https://pubmed.ncbi.nlm.nih.gov/29539807

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