Zobrazeno 1 - 10
of 20
pro vyhledávání: '"C. J. F. Bichard"'
The preparation of the δ-heptonolactones, 4- O -benzyl- D - glycero - D - D - gulo -heptono-1,5-lactoneand 4- O -benzyl- D - glycero - D - allo -heptono-1,5-lactone, by Kiliani reactions on 3- O -benzylglucose and 3- O -benzylallose are reported; ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0011cd16d297a921420dc3e81b0ada
https://ora.ox.ac.uk/objects/uuid:a7eee170-786e-4a4f-b76d-4f1a3af64f65
https://ora.ox.ac.uk/objects/uuid:a7eee170-786e-4a4f-b76d-4f1a3af64f65
Autor:
Maria Kontou, H. S. Tsitoura, Louise N. Johnson, K.R. Acharya, C. J. F. Bichard, K.A. Watson, Spyros E. Zographos, Demetres D. Leonidas, E. P. Mitchell, George W. J. Fleet, Nikos G. Oikonomakos, Jong Chan Son
alpha-D-glucose is a weak inhibitor (Ki = 1.7 mM) of glycogen phosphorylase (GP) and acts as physiological regulator of hepatic glycogen metabolism; it binds to GP at the catalytic site and stabilizes the inactive T state of the enzyme promoting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b4e8773c0f89d62eb8d10ee6f38a0b
https://doi.org/10.1007/bf03188920
https://doi.org/10.1007/bf03188920
Autor:
C. J. F. Bichard, Joseph R. Wheatley, George W. J. Fleet, David Hughes, Tilmann W. Brandstetter, Juan C. Estévez
A practical synthesis of epimeric C-glycosides of glucofuranose from the cheap gluco-heptono-1,4-lactone is reported; the ring contractions of 2-O-triflates of protected gluco-heptono-1,5-lactones are discussed. No tetrahydropyrancarboxylates were is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52cbdffa1e2add5634d3a8a2b81b4031
https://ora.ox.ac.uk/objects/uuid:9c13055e-30be-40de-82eb-996f07b089c0
https://ora.ox.ac.uk/objects/uuid:9c13055e-30be-40de-82eb-996f07b089c0
Autor:
K. Vogt, O. Doherty, C. J. F. Bichard, L. Pearce, Nigel Ramsden, Antony J. Fairbanks, George W. J. Fleet, David J. Watkin
Publikováno v:
ChemInform. 22
The preparation and characterisation of some derivatives of α-hydroxy-δ-lactones, in which the δ-carbon substituent on the lactone ring is trans to an adjacent isopropylidene protected diol, are described; the X-ray crystal structures of 3,4-O-iso
Autor:
George W. J. Fleet, David R. Brown, Simon J. Mantell, J. Saunders, B. M. Skead, C. J. F. Bichard, S. Choi, Antony J. Fairbanks, Jong Chan Son, Paul M. Myerscough
Publikováno v:
ChemInform. 24
Autor:
Ian Bruce, C. J. F. Bichard, George W. J. Fleet, David Hughes, Aarti Girdhar, David J. Watkin
Publikováno v:
ChemInform. 24
The preparation of 3,5-(R)-O-benzylidene-D-glycero-D-gulo-heptono-1,4-lactone, a readily available and powerful chiron, is described; other benzylidene derivatives of heptono-1,4-lactones are characterised. The X-ray crystal structure of 3,5(R):6,7(R
Autor:
David R. Brown, George W. J. Fleet, Jong Chan Son, Simon J. Mantell, David Hughes, C. J. F. Bichard, Joseph R. Wheatley
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 25
The preparation of the δ-heptonolactones, 4- O -benzyl- D - glycero - D - D - gulo -heptono-1,5-lactoneand 4- O -benzyl- D - glycero - D - allo -heptono-1,5-lactone, by Kiliani reactions on 3- O -benzylglucose and 3- O -benzylallose are reported; ac
Autor:
George W. J. Fleet, Nikos G. Oikonomakos, Mark R. Wormald, Spyros E. Zographos, C. J. F. Bichard, Kimberly A. Watson, Louise N. Johnson, Demetra D. Koutra, E. P. Mitchell
Publikováno v:
ChemInform. 26
The synthesis of two epimeric spirohydantoins of glucopyranose provides the first examples of pyranose analogues of hydantocidin: molecular modelling correctly predicted that one of the epimers would be a potent inhibitor of glycogen phosphorylase. T
Autor:
Tilmann W. Brandstetter, C. J. F. Bichard, Juan C. Estévez, David Hughes, Joseph R. Wheatley, George W. J. Fleet
Publikováno v:
ChemInform. 28
A practical synthesis of epimeric C-glycosides of glucofuranose from the cheap gluco-heptono-1,4-lactone is reported; the ring contractions of 2-O-triflates of protected gluco-heptono-1,5-lactones are discussed. No tetrahydropyrancarboxylates were is