Zobrazeno 1 - 8
of 8
pro vyhledávání: '"C. J. Doecke"'
Autor:
R. Gasser, John O. Miners, U. A. Meyer, Maurice E. Veronese, Peter I. Mackenzie, Donald J. Birkett, D. L. P. Rees, C. J. Doecke, Michael E. McManus
Publikováno v:
Biochemical Journal. 289:533-538
Evidence from human studies in vivo and in vitro strongly suggests that the methylhydroxylation of tolbutamide and the 4-hydroxylation of phenytoin, the major pathways in the elimination of these two drugs, are catalysed by the same cytochrome P-450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7092bd29713095414092ca244734af77
https://doi.org/10.1042/bj2890533
https://doi.org/10.1042/bj2890533
Autor:
John O. Miners, Peter I. Mackenzie, Maurice E. Veronese, Michael E. McManus, Donald J. Birkett, C. J. Doecke
Publikováno v:
Biochemical and Biophysical Research Communications. 175:1112-1118
A human cytochrome P4502C9 cDNA clone has been isolated from a human liver bacteriophage Lambda gt11 library using oligonucleotide probes. Expression of the 1762 base pair cDNA in COS cells demonstrated that the encoded enzyme has a molecular mass of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f8805e5cef1276fbe9ee2a99307566
https://doi.org/10.1016/0006-291x(91)91680-b
https://doi.org/10.1016/0006-291x(91)91680-b
Publikováno v:
Biochemical and Biophysical Research Communications. 166:860-866
The ability of rabbit liver microsomes to 4-hydroxylate phenytoin to 5-(4-hydroxyphenyl)-5-phenylhydantoin was studied. No significant difference was observed between the capacity of control and rifampicin, phenobarbital, acetone, 2,3,7,8-tetrachloro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efad637c665531cf000daf7c568a6a62
https://doi.org/10.1016/0006-291x(90)90889-u
https://doi.org/10.1016/0006-291x(90)90889-u
Autor:
C J, Doecke
Publikováno v:
Journal of quality in clinical practice. 19(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b9035832b9644962ffdfbecb14955fd
https://pubmed.ncbi.nlm.nih.gov/10096715
https://pubmed.ncbi.nlm.nih.gov/10096715
Publikováno v:
Anaesthesia and intensive care. 23(4)
The efficacy of ginger for the prevention of postoperative nausea and vomiting was studied in a double-blind, randomized, controlled trial in 108 ASA 1 or 2 patients undergoing gynaecological laparoscopic surgery under general anaesthesia. Patients r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147b57c861bb3fbf150e5b7cf77a6246
https://pubmed.ncbi.nlm.nih.gov/7485935
https://pubmed.ncbi.nlm.nih.gov/7485935
Publikováno v:
Australian and New Zealand journal of medicine. 21(3)
We report a comparison of warfarin treatment outcomes in 172 inpatients in two general hospitals randomly assigned to commence warfarin therapy by one of two methods; the first where warfarin dosage was determined using a flexible dose induction prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815e9aad81a7d9cb521b8cbf7887e6f5
https://pubmed.ncbi.nlm.nih.gov/1953510
https://pubmed.ncbi.nlm.nih.gov/1953510
Autor:
John O. Miners, C. J. Doecke, S. M. Pond, Maurice E. Veronese, Donald J. Birkett, L. N. Sansom, Michael E. McManus
1. The metabolic interaction of phenytoin and tolbutamide in human liver microsomes was investigated. 2. Phenytoin 4-hydroxylation (mean Km 29.6 microM, n = 3) was competitively inhibited by tolbutamide (mean Ki 106.2 microM, n = 3) and tolbutamide m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b080942147c1fd50273338bbd910a9
https://europepmc.org/articles/PMC1368377/
https://europepmc.org/articles/PMC1368377/
Autor:
Lloyd Sansom, Roy G. Beran, Philip E. Stanley, C. J. Doecke, W. J. O'Reilly, Graham J. Schapel, Phillip A. Reece, R. H. C. Rischbieth
Publikováno v:
European journal of clinical pharmacology. 17(1)
Pharmacokinetic analysis of the plasma valproic acid concentration-time course, following a single oral dose (600 mg) of sodium valproate, was performed in 20 epileptic patients as an aid to the prediction of a proper chronic dosage regimen. A simple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89cbe72c89215170b75e0a273f65917e
https://pubmed.ncbi.nlm.nih.gov/6768573
https://pubmed.ncbi.nlm.nih.gov/6768573