Zobrazeno 1 - 10
of 84
pro vyhledávání: '"C. I. Ragan"'
Publikováno v:
Journal of Biological Chemistry. 269:16020-16028
Antibodies specific for subunits of the gamma-aminobutyric acid A (GABAA) receptor have been used to immunoprecipitate [3H]muscimol, [3H]Ro 15-4513, and [3H]Ro 15-1788 binding sites from deoxycholate-solubilized preparations of rat cerebellum. Of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76489d7b283cf7003263f62852446da6
https://doi.org/10.1016/s0021-9258(17)33967-4
https://doi.org/10.1016/s0021-9258(17)33967-4
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1470-1474
An in vitro tissue culture cell model system for investigating the biochemical mechanisms involved in the neurodegenerative actions of beta-amyloid has been established. Using rat pheochromocytoma PC12 cells, it was found that an early, specific resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5b71580d138f99c5363f8e733e9221
https://doi.org/10.1073/pnas.91.4.1470
https://doi.org/10.1073/pnas.91.4.1470
Autor:
Stephen B. Freedman, Smita Patel, F. Emms, Shil Patel, C. I. Ragan, Ian Collins, Rosemarie Marwood, Howard B. Broughton, Richard G. Ball, Michael Rowley, Raymond Baker, Paul D. Leeson, William B Davey
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c9eb90da8f4c856d11aa2e4d21fb7f
https://doi.org/10.1002/chin.199746141
https://doi.org/10.1002/chin.199746141
Autor:
K Quirk, C I Ragan, Eric A. Barnard, P C Harkness, Paul J. Whiting, B. Le Bourdelles, Ruth M. McKernan, K. L. Hadingham, A. L. Horne, John A. Kemp
Publikováno v:
Proceedings of the National Academy of Sciences. 89:6378-6382
The differential sensitivity of type A gamma-aminobutyric acid (GABAA) receptors to benzodiazepine ligands seen in the mammalian nervous system is thought to be generated by the existence of a number of different receptor subtypes, assembled from a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f474aa3ff5906690d76a930a1bb3190e
https://doi.org/10.1073/pnas.89.14.6378
https://doi.org/10.1073/pnas.89.14.6378
Autor:
Martin Richard Teall, R. Baker, E.A. Harley, Paul D. Leeson, C I Ragan, Stephen Robert Fletcher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 2:627-630
Hydroxymethylenebisphosphonate derivatives have been found to be competitive inhibitors of myo-inositol monophosphatase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb1dcd92f2791987078560756f43b9b
https://doi.org/10.1016/s0960-894x(01)81212-9
https://doi.org/10.1016/s0960-894x(01)81212-9
Autor:
Maria S. Meinz, Richard W. Burg, Gerald F. Bills, G G Reid, L. Guariglia, C I Ragan, Robert A. Giacobbe, Yiu-Kuen T. Lam, Susan S. Honeycutt, R G Jackson, Sagrario Mochales, Richard L. Monaghan, J. J. Maguire, D. L. Zink, L. Huang, Li Kong, A. T. Mcknight, Carol F. Wichmann
Publikováno v:
The Journal of Antibiotics. 45:1397-1402
A novel inositol mono-phosphatase inhibitor, L-671, 776 (1), was discovered from a culture of the hyphomycete, Memnoniella echinata (ATCC 20928). 1 has a molecular weight of 388 and a molecular formula of C23H32O5. The mode of inhibition is non-compe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd8d3e396f266f7677f61e6631dd314
https://doi.org/10.7164/antibiotics.45.1397
https://doi.org/10.7164/antibiotics.45.1397
Autor:
J. G. Lindsay, S. P. M. Fussey, Margaret F. Bassendine, Stephen J. Yeaman, S. M. West, O.F.W. James, C. I. Ragan
Publikováno v:
Clinical Science. 80:451-455
1. In primary biliary cirrhosis, the major M2 autoantigen, reacting with antimitochondrial antibodies in sera from >90% of patients, has been identified as the E2 component of the pyruvate dehydrogenase complex. However, two recent reports suggest th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc217239457f1361e98822ccbde90a11
https://doi.org/10.1042/cs0800451
https://doi.org/10.1042/cs0800451
Publikováno v:
Biochemical Journal. 272:465-468
Bovine brain inositol monophosphatase is rapidly cleaved by endoprotease lys-C at a single site in the absence of SDS. Further sites are revealed only after prolonged incubation with high concentrations of protease. The initial cleavage occurs near o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406c579132275e8b51947e70b74f146f
https://doi.org/10.1042/bj2720465
https://doi.org/10.1042/bj2720465
Publikováno v:
Biochemical Journal. 269:623-628
The 5-HT3 hydroxytryptamine receptor from NCB 20 cells was solubilized and the molecular and hydrodynamic properties of the receptor were investigated. The receptor was identified by binding of the radioligand 3-NN′-[3H]dimethyl-8-azabicyclo[3.2.1]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96852a49665687a517c4f69e60ad3c5
https://doi.org/10.1042/bj2690623
https://doi.org/10.1042/bj2690623
Autor:
C O Kneen, G I Stevenson, K Quirk, Christopher John Swain, C I Ragan, Ruth M. McKernan, N P Gillard
Publikováno v:
Journal of Biological Chemistry. 265:13572-13577
A 5-hydroxytryptamine 5-HT3 receptor binding site has been purified from deoxycholate-solubilized NCB20 cell membranes. Purification (1,700-fold) was achieved in one step by affinity chromatography with L-685,603 immobilized on agarose. The 5-HT3 sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3056ec419b5a4250eb6ea4ea8228c57
https://doi.org/10.1016/s0021-9258(18)77386-9
https://doi.org/10.1016/s0021-9258(18)77386-9