Zobrazeno 1 - 10
of 911
pro vyhledávání: '"C. Hendrickson"'
Autor:
Atsushi Tanaka, Makiko Ogawa, Yihua Zhou, Ronald C. Hendrickson, Matthew M. Miele, Zhuoning Li, David S. Klimstra, Julia Y. Wang, Michael H. A. Roehrl
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract Acinar cell carcinoma (ACC) and pancreatoblastoma (PBL) are rare pancreatic malignancies with acinar differentiation. Proteogenomic profiling of ACC and PBL revealed distinct protein expression patterns compared to pancreatic ductal adenocar
Externí odkaz:
https://doaj.org/article/fcb1a2cb83e44e2bbcaa159805c9eca9
Autor:
Alexander H. Settle, Benjamin Y. Winer, Miguel M. de Jesus, Lauren Seeman, Zhaoquan Wang, Eric Chan, Yevgeniy Romin, Zhuoning Li, Matthew M. Miele, Ronald C. Hendrickson, Daan Vorselen, Justin S. A. Perry, Morgan Huse
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Phagocytosis is an intensely physical process that depends on the mechanical properties of both the phagocytic cell and its chosen target. Here, we employed differentially deformable hydrogel microparticles to examine the role of cargo rigid
Externí odkaz:
https://doaj.org/article/7bde948fab0947f0a3ebd774da92a46f
Autor:
Christopher P. Wardlaw, Matthew M. Miele, Zhuoning Li, Ronald C. Hendrickson, John H.J. Petrini
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102843- (2024)
Summary: Ubiquitin-like protein ISG15 plays an important role in an array of cellular functions via its covalent attachment to target proteins (ISGylation). Here, we present a protocol for the identification of ISGylated proteins that avoids the cave
Externí odkaz:
https://doaj.org/article/d50ab92c3a204377acfc589d3b9f06be
Autor:
Atsushi Tanaka, Makiko Ogawa, Yihua Zhou, Kei Namba, Ronald C. Hendrickson, Matthew M. Miele, Zhuoning Li, David S. Klimstra, Patrick G. Buckley, Jeffrey Gulcher, Julia Y. Wang, Michael H.A. Roehrl
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113810- (2024)
Summary: Metastatic progression of colorectal adenocarcinoma (CRC) remains poorly understood and poses significant challenges for treatment. To overcome these challenges, we performed multiomics analyses of primary CRC and liver metastases. Genomic a
Externí odkaz:
https://doaj.org/article/f4e4d723c6044042aa3cf7bf829ec054
Autor:
Rebecca C. Hendrickson, Catherine A. McCall, Aaron F. Rosser, Kathleen F. Pagulayan, Bernard P. Chang, Ellen D. Sano, Ronald G. Thomas, Murray A. Raskind
Publikováno v:
Sleep Medicine: X, Vol 5, Iss , Pp 100067- (2023)
Objective/Background: Healthcare workers have experienced high rates of psychiatric symptom burden and occupational attrition during the COVID-19 pandemic. Identifying contributory factors can inform prevention and mitigation measures. Here, we explo
Externí odkaz:
https://doaj.org/article/acf2c7c4880444c89da1b8cbb683b2f9
Autor:
Antonio Strillacci, Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng, Brian Houck-Loomis, David Brown, Michael F. Berger, Ronald C. Hendrickson, Qing Chang, Elisa de Stanchina, Fresia Pareja, Jorge S. Reis-Filho, Ramya Segu Rajappachetty, Isabella Del Priore, Bo Liu, Yanyan Cai, Alex Penson, Chiara Mastroleo, Marjan Berishaj, Francesca Borsetti, Enzo Spisni, David Lyden, Sarat Chandarlapaty, Jacqueline Bromberg
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Estrogen receptor alpha (ERα) drives mammary gland development and breast cancer (BC) growth through an evolutionarily conserved linkage of DNA binding and hormone activation functions. Therapeutic targeting of the hormone binding pocket is
Externí odkaz:
https://doaj.org/article/f78ea24d939745a8868b8fcd4d4bff37
Autor:
Ryan C. Hendrickson
During President Barack Obama's first term in office, the United States expanded its military presence in Afghanistan and increased drone missile strikes across Pakistan, Yemen, and Somalia. The administration also deployed the military to combat pir
Autor:
Divya Ramchandani, Mirela Berisa, Diamile A. Tavarez, Zhuoning Li, Matthew Miele, Yang Bai, Sharrell B. Lee, Yi Ban, Noah Dephoure, Ronald C. Hendrickson, Suzanne M. Cloonan, Dingcheng Gao, Justin R. Cross, Linda T. Vahdat, Vivek Mittal
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Copper depletion has been reported to improve survival in patients with triple negative breast cancer (TNBC) but the underlying mechanisms are not completely understood. Here, the authors show that copper chelation reduces mitochondrial oxidative pho
Externí odkaz:
https://doaj.org/article/84f3fe60af3143d88e9dc7a8c45b3a7d
Autor:
Paulina M. Wojnarowicz, Marta Garcia Escolano, Yun-Han Huang, Bina Desai, Yvette Chin, Riddhi Shah, Sijia Xu, Saurabh Yadav, Sergey Yaklichkin, Ouathek Ouerfelli, Rajesh Kumar Soni, John Philip, David C. Montrose, John H. Healey, Vinagolu K. Rajasekhar, William A. Garland, Jeremy Ratiu, Yuan Zhuang, Larry Norton, Neal Rosen, Ronald C. Hendrickson, Xi Kathy Zhou, Antonio Iavarone, Joan Massague, Andrew J. Dannenberg, Anna Lasorella, Robert Benezra
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)
Abstract ID proteins are helix-loop-helix (HLH) transcriptional regulators frequently overexpressed in cancer. ID proteins inhibit basic-HLH transcription factors often blocking differentiation and sustaining proliferation. A small-molecule, AGX51, t
Externí odkaz:
https://doaj.org/article/fcc94ce778e043e9991e8da7d30777e4
Autor:
Atsushi Tanaka, Julia Y. Wang, Jinru Shia, Yihua Zhou, Makiko Ogawa, Ronald C. Hendrickson, David S. Klimstra, Michael H. Roehrl
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract DEAD-box RNA helicase DDX21 (also named nucleolar RNA helicase 2) is a nuclear autoantigen with undefined roles in cancer. To explore possible roles of autoimmune recognition in cancer immunity, we examined DDX21 protein expression in colore
Externí odkaz:
https://doaj.org/article/c2c9bb8563534cf2977d98f7085af19d