Zobrazeno 1 - 10
of 79
pro vyhledávání: '"C. Hackbarth"'
Publikováno v:
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bad5d7a82839c9df79c420ff1d980064
https://doi.org/10.1055/s-0040-1703289
https://doi.org/10.1055/s-0040-1703289
Publikováno v:
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68034e68aa3d53ea0dba99a920e30f93
https://doi.org/10.1055/s-0038-1668443
https://doi.org/10.1055/s-0038-1668443
Publikováno v:
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84fb16d54c341ae3a5c8f2d375a18ce9
https://doi.org/10.1055/s-0037-1605505
https://doi.org/10.1055/s-0037-1605505
Autor:
Steven R. Larson, Kent C. Hackbarth, Ronald G. Brisbois, Percy Y. Griffin, Aubrey J. Ellison, Alexandra M. Bergan
Publikováno v:
Tetrahedron Letters. 54:272-276
The 1,2,3-triazole scaffold is an important pharmacophore and a versatile, increasingly leveraged, substructure in biochemical, materials, polymer, and metal-coordinating applications. Continuing advances in 1,2,3-triazole construction, by either non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ae2c8a154ff3eb37b7ad4abd2aa0ef
https://doi.org/10.1016/j.tetlet.2012.11.019
https://doi.org/10.1016/j.tetlet.2012.11.019
Publikováno v:
Organometallics. 31:2437-2444
Oxidative decarbonylation of (η5-C5R5)Mo(CO)3X and isoelectronic four-legged piano-stool Mo(II) precursors to homogeneous olefin epoxidation catalysts has garnered significant attention as an alter...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66554e2fcaa2dcb852920eb9b339580
https://doi.org/10.1021/om300057n
https://doi.org/10.1021/om300057n
Publikováno v:
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie. 140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::704800e2fff90ef9841ef6cd8c80fc24
https://doi.org/10.1055/s-0035-1559928
https://doi.org/10.1055/s-0035-1559928
Autor:
Priyadarshini Jaishankar, Dinesh V. Patel, Adam R. Renslo, Mikhail F. Gordeev, C. Hackbarth, Sara L. Lopez, Revathy Venkatachalam
Publikováno v:
Journal of Medicinal Chemistry. 48:5009-5024
The oxazolidinones are a new class of synthetic antibacterials effective against a broad range of pathogenic Gram-positive bacteria, including multi-drug-resistant strains. Linezolid is the first drug from this class to reach the market and has becom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6562a90edc2b02e4e2911dc69b118ef2
https://doi.org/10.1021/jm058204j
https://doi.org/10.1021/jm058204j
Autor:
Gary W. Luehr, Jonathan M. Evans, Gage James R, Barbachyn Michael R, Joaquim Trias, Christian N. Parker, Lee S. Banitt, Gary E. Zurenko, Sara E. Morin, Dinesh V. Patel, Mikhail F. Gordeev, C. Hackbarth, Richard White, Marcela Gomez
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4213-4216
Antimicrobial compounds incorporating oxazolidinone and quinolone pharmacophore substructures have been synthesized and evaluated. Representative analogues 2, 5, and 6 display an improved potency versus linezolid against gram-positive and fastidious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d313a2797a32d31df009120095a7ca
https://doi.org/10.1016/j.bmcl.2003.07.021
https://doi.org/10.1016/j.bmcl.2003.07.021
Autor:
C. Hackbarth, Wen Wang, Charlotte Wu, Rakesh K. Jain, Dinesh V. Patel, A. Sundram, Richard C. White, Sara Lopez, Joaquim Trias, Dawn Chen, Zhengyu Yuan, G. Neckermann, Beat Weidmann, Neil S. Ryder
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4223-4228
We report the synthesis and biological activity of analogues of VRC3375 (N-hydroxy-3-R-butyl-3-[(2-S-(tert-butoxycarbonyl)-pyrrolidin-1-ylcarbonyl]propionamide), an orally active peptide deformylase inhibitor. This study explores the structure–acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dd81795156bc5b45898bcc74e7d22f
https://doi.org/10.1016/j.bmcl.2003.07.020
https://doi.org/10.1016/j.bmcl.2003.07.020
Autor:
Dinesh V. Patel, Wen Wang, Joaquim Trias, Geoffrey B. Dreyer, Charlotte Wu, Peter S. Margolis, C. Hackbarth, Zhengyu Yuan, Richard White, Zi-Jie Ni, Dawn Chen, Dennis C. Young
Publikováno v:
Biochemistry. 39:1256-1262
Peptide deformylase (PDF) is essential in prokaryotes and absent in mammalian cells, thus making it an attractive target for the discovery of novel antibiotics. We have identified actinonin, a naturally occurring antibacterial agent, as a potent PDF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed699e548600f2145f0d0e703fe992d6
https://doi.org/10.1021/bi992245y
https://doi.org/10.1021/bi992245y