Zobrazeno 1 - 10 of 103 pro vyhledávání: '"C. H. W. Horne"'
1
Wild-Type Estrogen Receptor Beta Expression in Normal and Neoplastic Paraffin-Embedded Tissues
Autor: Julie Gray, Mark Rees, Ian Marshall, Ian D. Milton, Kenneth Mitchell, Mik Pinkney, Gary McIntosh, C. H. W. Horne, Nigel H. Piggott
Publikováno v: Hybridoma and Hybridomics. 23:11-18
Recently, several antibodies have allowed the detection of estrogen receptor beta (ER-beta) in paraffin-embedded tissue; however, these attempts have failed to specifically identify the wild-type form and revealed technical difficulties such as the n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3944b30f2868c8946dc74cc459bab548
https://doi.org/10.1089/153685904322771971
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2
Expression of topoisomerase III α in normal and neoplastic tissues determined by immunohistochemistry using novel monoclonal antibody
Autor: M Steward, John Anderson, C. H. W. Horne, A J Lodge, B. Haugk, F Fenwick, B. Angus, S W Ng
Publikováno v: British Journal of Cancer
Topoisomerases are nuclear enzymes that modulate the topological structure of DNA in order to facilitate cellular events such as replication and transcription. These enzymes are also the cellular targets of certain classes of chemotherapeutic agents
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6e1566e8686ad21085b9e4a20d678a
http://europepmc.org/articles/PMC2374664
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3
Monoclonal antibodies recognizing CD5, CD10 and CD23 in formalin-fixed, paraffin-embedded tissue: production and assessment of their value in the diagnosis of small B-cell lymphoma
Autor: P. Watson, Nigel H. Piggott, I. D. Milton, C. H. W. Horne, S. Smith, Stephen J. Proctor, Brian Angus, A. Lodge, H Bell, G. G. Mcintosh, Penelope R. A. Taylor, John Anderson, M Steward, Katrina M Wood, F. Jack
Publikováno v: Histopathology. 36:145-150
Aims Assessment of the expression of antigens CD5, CD10 and CD23 can be of value in the differential diagnosis of small B-cell lymphoma. Correct subclassification is important since optimal treatment regimes differ between the subtypes. The aim of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::335160058629e640a470c5e9705475f2
https://doi.org/10.1046/j.1365-2559.2000.00813.x
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5
New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry
Autor: Bruce R. Westley, Nigel Piggot, T. W. J. Lennard, Michael J. Carter, C. H. W. Horne, Brian Angus, Geoffrey L. Toms, Linda Henry, Ian D. Milton, Debra J. Bevitt
Publikováno v: The Journal of Pathology. 183:228-232
Assessment of oestrogen and progesterone receptors (ER and PgR) in breast cancer is widely used for the prediction of response to endocrine therapy and as a prognostic marker. Cytosolic assays have been replaced in many centres by immunochemical tech
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e21a82a55f734f5c6fae6630c8dd54d
https://doi.org/10.1002/(sici)1096-9896(199710)183:2<228::aid-path895>3.0.co
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7
A novel quantitative immunoassay system for p53 using antibodies selected for optimum designation of p53 status
Autor: Gary McIntosh, C. H. W. Horne, John Anderson, M. D. Thomas, D. M. Mckenna, R. Johnstone, T. W. J. Lennard, A. H. Parr, Brian Angus
Publikováno v: Journal of Clinical Pathology. 50:143-147
AIM: To develop a highly sensitive and specific enzyme linked immunosorbent assay (ELISA) system for analysis of p53 protein in cancer lysates. METHODS: The anti-p53 monoclonal antibodies DO7, 1801, BP53.12, and 421, and anti-p53 polyclonal antiserum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c2a18101e0942aa5d253729a659a9e
https://doi.org/10.1136/jcp.50.2.143
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8
Production and characterization of a new monoclonal antibody effective in recognizing the CD3 T‐cell associated antigen in formalin‐fixed embedded tissue
Autor: Brian Angus, M Steward, R. Bishop, I. D. Milton, C. H. W. Horne, Nigel H. Piggott
Publikováno v: Histopathology. 30:16-22
Phenotypic analysis of lymphoproliferative disorders is now considered mandatory for accurate classification which is the basis for optimum patient management. This is presently carried out in most cases using a range of antibodies recognizing B and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3633168345fb0f8e56ac379c4bc92865
https://doi.org/10.1046/j.1365-2559.1997.d01-553.x
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9
RETINOBLASTOMA PROTEIN IN HUMAN BREAST CARCINOMA: IMMUNOHISTOCHEMICAL STUDY USING A NEW MONOCLONAL ANTIBODY EFFECTIVE ON ROUTINELY PROCESSED TISSUES
Autor: Myles D. Thomas, Dina Tiniakos, Glenda M. Horne, Thomas W. J. Lennard, John Anderson, Pernille Autzen, C. H. W. Horne, J. A. Henry, Gary G. McINTOSH, Brian Angus, J B Reed
Publikováno v: The Journal of Pathology. 180:65-70
Cyclic phosphorylation/dephosphorylation of the retinoblastoma gene product (pRB) has been found to play a central role in the progression of the normal cell cycle, through modulation of the activity of the E2F family of transcription factors. Mutati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c798bd9864881336d631261f67d994b
https://doi.org/10.1002/(sici)1096-9896(199609)180:1<65::aid-path607>3.0.co
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10
c-erbB -2 and p53 expression in breast cancer fine needle aspirates
Autor: H. Greenwood, C. H. W. Horne, K. B. Robinson, A. I. M. Cook, P. Cullen, B. Angus, Dina Tiniakos
Publikováno v: Cytopathology. 7:178-186
The aim of this study was to co-evaluate c-erb B-2 and p53 protein expression in breast cancer fine needle aspirates (FNA) and to compare this with histological variables and the immunohistochemical phenotype of the tumours. Furthermore, we assessed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36540bf52d5864475bfe8670baa38aaf
https://doi.org/10.1046/j.1365-2303.1996.39482394.x
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