Zobrazeno 1 - 10
of 46
pro vyhledávání: '"C. H. Quek"'
Autor:
Kam W. Leong, Yiling Zhong, Dan Shao, Jianati Dawulieti, Shu Sheng, Chao Yang, Feng Liu, Huayu Tian, Jie Zhou, Yanbing Wang, Yongqiang Xiao, C. H. Quek, Xuesi Chen
Publikováno v:
Matter. 4:3677-3695
Summary Treatments that target single mediators of sepsis have failed to reduce its high mortality rate. Here we developed multifunctional tannic acid-Zn2+-gentamicin nanoparticles (TA-Zn-Gen NPs) that target multiple mediators of sepsis to improve s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a44ef768b08cca2d9945db586ea12a59
https://doi.org/10.1016/j.matt.2021.09.001
https://doi.org/10.1016/j.matt.2021.09.001
Autor:
Dan Shao, Kam W. Leong, Jie Zhou, Feng Liu, Yanbing Wang, Yongqiang Xiao, Huayu Tian, Yanhui Li, Yiling Zhong, C. H. Quek, Zhiming Hu, Heshi Liu, Xuesi Chen, Shu Sheng
Publikováno v:
Nano Lett
Circulating cell-free DNA (cfDNA) released by damaged cells causes inflammation and has been associated with the progression of sepsis. One proposed strategy to treat sepsis is to scavenge this inflammatory circulating cfDNA. Here, we develop a cfDNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5e105e8c45ca69c30cd41443ee1f5d
https://doi.org/10.1021/acs.nanolett.0c04759
https://doi.org/10.1021/acs.nanolett.0c04759
Autor:
Dan Shao, Hanyao Huang, Hye Sung Kim, Lei Zhao, Sheng-Min Zhang, Baoding Huang, Bing Shi, Tzu-Chieh Ho, Weiyi Pan, Kam W. Leong, Jiayu Shi, C. H. Quek, Yeh-Hsing Lao, Yi-Fan Wang
Periodontitis is a common type of inflammatory bone loss and is a risk factor for systemic diseases. The pathogenesis of periodontitis relies on inflammatory dysregulation, which represents a target for new therapeutic strategies to treat periodontit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f65124a100b5f70dad948047917d2d
https://doi.org/10.21203/rs.3.rs-139744/v1
https://doi.org/10.21203/rs.3.rs-139744/v1
Autor:
Kam W. Leong, Sihong Wang, Rachel L. Mintz, Yeh-Hsing Lao, Boyuan Chen, Chun-Wei Chi, Jing Han, C. H. Quek, Dan Shao, Mingqiang Li, Siyu He
Publikováno v:
Bioengineering & Translational Medicine, Vol 5, Iss 1, Pp n/a-n/a (2020)
For patients carrying BRCA1 mutations, at least one‐third develop triple negative breast cancer (TNBC). Not only is TNBC difficult to treat due to the lack of molecular target receptors, but BRCA1 mutations (BRCA1m) also result in chemotherapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b30a09b954f2760862505fd7de2bfa8
https://doaj.org/article/8aa2dd66bd4e4311a93ad83ab768f12f
https://doaj.org/article/8aa2dd66bd4e4311a93ad83ab768f12f
Autor:
Ha Yeun Ji, Ki-Bum Lee, Smruthi Suryaprakash, Dantong Huang, Hyeon-Yeol Cho, Mingqiang Li, Rachel L. Mintz, Hanze Hu, Kam W. Leong, Dan Shao, C. H. Quek, Juli R. Bagó, Shawn Hingtgen, Yeh-Hsing Lao
Publikováno v:
Nano letters. 19(3)
Mesenchymal stem cell (MSC) has been increasingly applied to cancer therapy because of its tumor-tropic capability. However, short retention at target tissue and limited payload option hinder the progress of MSC-based cancer therapy. Herein, we propo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dc63b0db2487830bf4f83832ec27d5
https://pubmed.ncbi.nlm.nih.gov/30773888
https://pubmed.ncbi.nlm.nih.gov/30773888
Autor:
C. H. Quek, Kam W. Leong
Publikováno v:
Nanomaterials, Vol 2, Iss 2, Pp 92-112 (2012)
Nanomaterials
Nanomaterials
Near-infrared (NIR) fluorescent probes offer advantages of high photon penetration, reduced light scattering and minimal autofluorescence from living tissues, rendering them valuable for noninvasive mapping of molecular events, assessment of therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2f22752ece80988a0f4221e46244a7
http://www.mdpi.com/2079-4991/2/2/92
http://www.mdpi.com/2079-4991/2/2/92
Autor:
Natelle C. H. Quek, Dora C. Leahy, David S. Bellows, John H. Miller, Jacqueline M. Barber, Peter T. Northcote
Publikováno v:
Journal of Natural Products. 74:809-815
Spectroscopy-guided chemical analysis of a marine sponge from the genus Plakortis, collected in Tonga, yielded seven new metabolites of polyketide origin, lehualides E-K (5-11), four of which incorporate various sulfur functionalities. The structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73a803df08106ba005d46772dfccf3d
https://doi.org/10.1021/np100868t
https://doi.org/10.1021/np100868t
Publikováno v:
Biomaterials. 30:1133-1142
Living tissues consist of groups of cells organized in a controlled manner to perform a specific function. Spatial distribution of cells within a three-dimensional matrix is critical for the success of any tissue-engineering construct. Fibers endowed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ec12b33d35e9fd6edb1d0ca28af28a
https://doi.org/10.1016/j.biomaterials.2008.11.003
https://doi.org/10.1016/j.biomaterials.2008.11.003
Autor:
Mah-Lee Ng, Chao Yin, Pao-Chun Lin, Cho-Hong Goh, C. H. Quek, Hanry Yu, Hai-Quan Mao, Kam W. Leong, Ser-Mien Chia, Xi Xu
Publikováno v:
Journal of Biotechnology. 118:434-447
Tissue engineering involves ex vivo seeding of anchorage-dependent mammalian cells onto scaffolds, or transplanting cells in vivo. The cell expansion currently requires repeated cell detachment from solid substrata by enzymatic, chemical or mechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2317a33a6396683d740be737e0cae83b
https://doi.org/10.1016/j.jbiotec.2005.05.012
https://doi.org/10.1016/j.jbiotec.2005.05.012
Autor:
Kam W. Leong, Jun Li, Hanry Yu, Tao Sun, Hai-Quan Mao, Leong Ming Gan, C. H. Quek, Melinda Ling Hou Chan
Publikováno v:
Scopus-Elsevier
New anionic polyelectrolyte tetra-copolymers with photo-crosslinkable 4-(4-methoxycinnamoyl)phenyl methacrylate monomer in addition to a HEMA-MMA-MAA ter-copolymer system were synthesized. The tetra-copolymers were used to form photo-crosslinkable mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3ef18469abe1b74c50086e87383ed7
https://doi.org/10.1016/j.biomaterials.2003.09.112
https://doi.org/10.1016/j.biomaterials.2003.09.112