Zobrazeno 1 - 10
of 26
pro vyhledávání: '"C. George Carlson"'
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 3, Pp 719-730 (2005)
The potential pathogenic role of increased NFκB signaling in passively stretched dystrophic skeletal muscle was examined by treating adult mdx mice with an agent that stabilized cytosolic IκB-α (pyrollidine dithiocarbamate, PDTC)and examining the
Externí odkaz:
https://doaj.org/article/ba0f9ad84e5f41aba359bac8cec5838e
Autor:
Christopher Borowy, Ravi Kumar, C. George Carlson, Cory Nielsen, Kimberly Jacinto, Ross M. Potter
Publikováno v:
Journal of Cellular Physiology. 232:1774-1793
The efficacy of two ActRIIB ligand-trapping agents (RAP-031 and RAP-435) in treating muscular dystrophy was examined by determining their morphological effects on the severely dystrophic triangularis sterni (TS) muscle of the mdx mouse, a model for D
Publikováno v:
Muscle & Nerve. 53:431-437
Introduction Previous experiments have indicated that in vivo administration of ursodeoxycholic acid (UDCA) inhibits nuclear NF-κB activation and has beneficial effects on the structure and function of dystrophic (mdx) muscle. We examined the effect
Publikováno v:
Journal of Cellular Physiology. 231:788-797
Inhibiting the NF-κB signaling pathway provides morphological and functional benefits for the mdx mouse, a model for Duchenne muscular dystrophy characterized by chronic elevations in the nuclear expression of p65, the transactivating component of t
Autor:
Cory, Nielsen, Ross M, Potter, Christopher, Borowy, Kimberly, Jacinto, Ravi, Kumar, C George, Carlson
Publikováno v:
Journal of cellular physiology. 232(7)
The efficacy of two ActRIIB ligand-trapping agents (RAP-031 and RAP-435) in treating muscular dystrophy was examined by determining their morphological effects on the severely dystrophic triangularis sterni (TS) muscle of the mdx mouse, a model for D
Autor:
Cathy Bledsoe, Jonas Berge, W. Tyler Winders, C. George Carlson, Eric Turin, Ashley Siegel, Beniamino Palmeiri, Gregory Millman, Jesse Lavin, John Rutter, Francesca Gatti
Publikováno v:
Neuromuscular Disorders. 19:131-139
The whole body tension (WBT) method was used to evaluate the hypothesis that long term treatment with NF-kappaB inhibitors improves the total forward pulling tension exerted by the limb musculature of the mdx mouse. Mdx mice exhibited significantly r
Publikováno v:
Journal of cellular physiology. 231(4)
Inhibiting the NF-κB signaling pathway provides morphological and functional benefits for the mdx mouse, a model for Duchenne muscular dystrophy characterized by chronic elevations in the nuclear expression of p65, the transactivating component of t
Autor:
Carter Kaminski, Cory Nielsen, Ross M. Potter, C. George Carlson, Kimberly Jacinto, Ravi Kumar, Christopher Borowy
Publikováno v:
The FASEB Journal. 29
Autor:
Christopher Borowy, Ross M. Potter, Cory Nielsen, C. George Carlson, Kimberly Jacinto, Ravi Kumar
Publikováno v:
The FASEB Journal. 29
Duchenne muscular dystrophy is characterized by repeated cycles of degeneration and regeneration ultimately leading to respiratory failure and death. Muscle growth is largely under the control of m...
Publikováno v:
American journal of translational research. 7(4)
The efficacy of two highly specific IκB-α kinase β (IKK-β) inhibitors in reducing the enhanced basal activation of the NF-κB pathway in dystrophic muscle was assessed by determining the effects of these inhibitors in increasing the expression of