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Akademický článek

Dissecting components of the Campylobacter jejuni fetMP-fetABCDEF gene cluster under iron limitation

Autor: Tomas Richardson-Sanchez, Anson C. K. Chan, Brendil Sabatino, Helen Lin, Erin C. Gaynor, Michael E. P. Murphy

Publikováno v: Microbiology Spectrum, Vol 12, Iss 1 (2024)

ABSTRACT Campylobacter jejuni is a leading cause of bacterial gastroenteritis worldwide. Acute infection can be an antecedent to highly debilitating long-term sequelae. The expression of iron acquisition systems is vital for C. jejuni to survive the

Externí odkaz: https://doaj.org/article/983e1be7015c46ff8f34e0d904fd628d

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Akademický článek

Multiple Campylobacter jejuni proteins affecting the peptidoglycan structure and the degree of helical cell curvature

Autor: Emilisa Frirdich, Jenny Vermeulen, Jacob Biboy, Waldemar Vollmer, Erin C. Gaynor

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

Campylobacter jejuni is a Gram-negative helical bacterium. Its helical morphology, maintained by the peptidoglycan (PG) layer, plays a key role in its transmission in the environment, colonization, and pathogenic properties. The previously characteri

Externí odkaz: https://doaj.org/article/975fb56cf7dd44b08c858f4f4d616f1f

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Male-specific association of the 2p25 region with suicide attempt in bipolar disorder

Autor: Rachel D. Reichman, Marie E. Gaine, Virginia L. Willour, Meredith G. Parsons, James B. Potash, Michael S. Chimenti, Peter P. Zandi, Eric T. Monson, Sophia C. Gaynor, Lalita Oonthonpan

Publikováno v: J Psychiatr Res

We previously conducted a genome-wide association study (GWAS) of attempted suicide within bipolar disorder, which implicated common variation in the 2p25 region primarily in males. The top association signal from our GWAS occurred in an intergenic r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2a3b8e35755873ac2108569d3989e0
https://doi.org/10.1016/j.jpsychires.2019.11.009

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Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder

Autor: Marie E. Gaine, James B. Potash, Virginia L. Willour, Sophia C. Gaynor, Peter P. Zandi, Rachel D. Reichman, Meredith G. Parsons, Eric T. Monson

Publikováno v: Am J Med Genet B Neuropsychiatr Genet

Glutamatergic signaling is the primary excitatory neurotransmission pathway in the brain, and its relationship to neuropsychiatric disorders is of considerable interest. Our previous attempted suicide genome-wide association study, and numerous studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f34da36cc6d3c1605e8a7fe36ec4e2
https://doi.org/10.1002/ajmg.b.32767

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Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni

Autor: Martin E. Tanner, Jacob A. Brockerman, Chang Sheng-Huei Lin, Jean-Pierre Simorre, Erin C. Gaynor, Jenny Vermeulen, Lawrence P. McIntosh, Anson C. K. Chan, Arvind Soni, Michael E. P. Murphy

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 296, pp.100528. ⟨10.1016/j.jbc.2021.100528⟩
The Journal of Biological Chemistry

International audience; The helical morphology of Campylobacter jejuni, a bacterium involved in host gut colonization and pathogenesis in humans, is determined by the structure of the peptidoglycan (PG) layer. This structure is dictated by trimming o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0e0e23388d36bc0f74269c64db3c73
https://hal.science/hal-03328690

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