Zobrazeno 1 - 10
of 111
pro vyhledávání: '"C. G. WERMUTH"'
Autor:
M. Chorghade, N. Koga, C. G. Wermuth, T.J. Perun, Charon Robin Ganellin, Paul W. Erhardt, J.G. Topliss, P. Lindberg, B.K. Trivedi, Antonio Monge
Publikováno v:
European Journal of Medicinal Chemistry. 35:1121-1125
This document has been elaborated by the IUPAC Medicinal Chemistry section and is backed by a large number of scientists, many of whom have had direct involvement and whose names appear at the end of the article. This work discusses the role that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b4c32d6298efa993c4cedd3a69dde4
https://doi.org/10.1016/s0223-5234(00)01196-x
https://doi.org/10.1016/s0223-5234(00)01196-x
Publikováno v:
Pure and Applied Chemistry. 70:1129-1143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9de25ec18e1a40815d0fafda64d1a75a
https://doi.org/10.1351/pac199870051129
https://doi.org/10.1351/pac199870051129
Autor:
C. G. Wermuth, F. Sautel, C. Pilon, Pierre Sokoloff, J. Diaz, D. Levesque, P. Simon, J.-C. Schwartz, A. Mann, Nathalie Griffon, J. Costentin
Publikováno v:
Biochemical Society Transactions. 24:193-198
Functional models for the dopamine D3 receptor N. Griffon*II, F. Sautel*, C. Pilon*, D. Levesque*, P. SokolofP, 1.-C. Schwartz*, J. Diazt, P. Simon*, J. Costentin*, A. Mann§ and C. G. Wermuthg *Unite de Neurobiologie et Pharrnacologie, Centre Paul B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453c964854aa683b04e01f4059b27c23
https://doi.org/10.1042/bst0240193
https://doi.org/10.1042/bst0240193
Autor:
C. G. Wermuth
Publikováno v:
ChemInform. 25
In the search for central cholinergic agents which do not derive from already well-known agonists such as arecoline, pilocarpine or oxotremorine, we selected minaprine [3-(beta-morpholinoethylamino)-4-methyl-6-phenyl-pyridazine dihydrochloride] as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fb07dfcb861f42d622a0857c7ec624
https://doi.org/10.1002/chin.199412216
https://doi.org/10.1002/chin.199412216
Autor:
C. G. WERMUTH
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dae5cb7897ca6d65c5af05798eb119d9
https://doi.org/10.1002/chin.199712310
https://doi.org/10.1002/chin.199712310
Publikováno v:
Journal of computer-aided molecular design. 15(5)
The paper describes the construction, validation and application of a structure-based 3D QSAR model of novel acetylcholinesterase (AChE) inhibitors. Initial use was made of four X-ray structures of AChE complexed with small, non-specific inhibitors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fd11d5129f62299f2ea570a292b434e
https://pubmed.ncbi.nlm.nih.gov/11394735
https://pubmed.ncbi.nlm.nih.gov/11394735
Autor:
A, Monge, M, Chorghade, P W, Erhardt, C R, Ganellin, N, Koga, P, Lindberg, T J, Perun, J G, Topliss, B K, Trivedi, C G, Wermuth
Publikováno v:
European journal of medicinal chemistry. 35(12)
This document has been elaborated by the IUPAC Medicinal Chemistry section and is backed by a large number of scientists, many of whom have had direct involvement and whose names appear at the end of the article. This work discusses the role that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9db93eef09fe06f53f5a5b135be47294
https://pubmed.ncbi.nlm.nih.gov/11248411
https://pubmed.ncbi.nlm.nih.gov/11248411
Publikováno v:
Journal of computer-aided molecular design. 11(4)
Our model of the human m1 muscarinic receptor has been refined on the basis of the recently published projection map of bovine rhodopsin. The refined model has a slightly different helix arrangement, which reveals the presence of an extra hydrophobic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a509a182bfd25bd20ea6fc460a872c46
https://pubmed.ncbi.nlm.nih.gov/9334899
https://pubmed.ncbi.nlm.nih.gov/9334899
Autor:
C G, Wermuth
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 48(2)
In the search for central cholinergic agents which do not derive from already well-known agonists such as arecoline, pilocarpine or oxotremorine, we selected minaprine [3-(beta-morpholinoethylamino)-4-methyl-6-phenyl-pyridazine dihydrochloride] as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12cb41c391cf3a47df6ab95a63afe93f
https://pubmed.ncbi.nlm.nih.gov/8494598
https://pubmed.ncbi.nlm.nih.gov/8494598