Zobrazeno 1 - 10
of 25
pro vyhledávání: '"C. Fiona Cullen"'
Autor:
Charlotte Repton, C Fiona Cullen, Mariana F A Costa, Christos Spanos, Juri Rappsilber, Hiroyuki Ohkura
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1009995 (2022)
Global regulation of spindle-associated proteins is crucial in oocytes due to the absence of centrosomes and their very large cytoplasmic volume, but little is known about how this is achieved beyond involvement of the Ran-importin pathway. We previo
Externí odkaz:
https://doaj.org/article/6cb74425aff44e2e90782b6fafd3e4a8
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001179 (2010)
The meiotic recombination checkpoint is a signalling pathway that blocks meiotic progression when the repair of DNA breaks formed during recombination is delayed. In comparison to the signalling pathway itself, however, the molecular targets of the c
Externí odkaz:
https://doaj.org/article/9f5a5a78f1a94949b907d75eae76084f
Autor:
Weiping Lu, C. Fiona Cullen, Russell S. Hamilton, Graeme Ball, Richard M. Parton, Hiroyuki Ohkura, Ilan Davis, Lei Yang
Publikováno v:
The Journal of Cell Biology
Parton, R, Hamilton, R, Ball, G, Yang, L, Cullen, F, Lu, W, Ohkura, H & Davis, I 2011, ' A PAR-1-dependent orientation gradient of dynamic microtubules directs posterior cargo transport in the Drosophila oocyte ', Journal of Cell Biology, vol. 194, no. 1, pp. 121-135 . https://doi.org/10.1083/jcb.201103160
Parton, R, Hamilton, R, Ball, G, Yang, L, Cullen, F, Lu, W, Ohkura, H & Davis, I 2011, ' A PAR-1-dependent orientation gradient of dynamic microtubules directs posterior cargo transport in the Drosophila oocyte ', Journal of Cell Biology, vol. 194, no. 1, pp. 121-135 . https://doi.org/10.1083/jcb.201103160
A PAR-1–mediated bias in microtubule organization in the Drosophila oocyte underlies posterior-directed mRNA transport.
Cytoskeletal organization is central to establishing cell polarity in various cellular contexts, including during messenger
Cytoskeletal organization is central to establishing cell polarity in various cellular contexts, including during messenger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27933d4f47c8dda96b0d1c5be4ca91de
https://doi.org/10.1083/jcb.201103160
https://doi.org/10.1083/jcb.201103160
Publikováno v:
The Journal of Cell Biology
Accurate chromosome segregation in meiosis requires dynamic changes in chromatin organization. In Drosophila melanogaster, upon completion of recombination, meiotic chromosomes form a single, compact cluster called the karyosome in an enlarged oocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b940422c4aae240e4b6f7e230919e984
https://doi.org/10.1083/jcb.200706067
https://doi.org/10.1083/jcb.200706067
Autor:
Gohta Goshima, A. Agata Głuszek, Kim S. McKim, Mariana F A Costa, Hiroyuki Ohkura, Rachel A. Battaglia, Wenjing Li, C. Fiona Cullen, Sarah J. Radford
Publikováno v:
Głuszek, A A, Cullen, C F, Li, W, Battaglia, R A, Radford, S J, Costa, M F, McKim, K S, Goshima, G & Ohkura, H 2015, ' The microtubule catastrophe promoter Sentin delays stable kinetochore-microtubule attachment in oocytes ', Journal of Cell Biology, vol. 211, no. 6, pp. 1113-20 . https://doi.org/10.1083/jcb.201507006
The Journal of Cell Biology
The Journal of Cell Biology
The microtubule catastrophe-promoting complex Sentin-EB1 delays stable kinetochore–microtubule attachment and facilitates bipolar attachment of homologous chromosomes in Drosophila oocytes.
The critical step in meiosis is to attach homologous
The critical step in meiosis is to attach homologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defe39af59cd131e40be14937d9ee710
https://www.pure.ed.ac.uk/ws/files/22100022/The_microtubule_catastrophe_promoter_Sentin_delays_stable.....pdf
https://www.pure.ed.ac.uk/ws/files/22100022/The_microtubule_catastrophe_promoter_Sentin_delays_stable.....pdf
Publikováno v:
The Journal of Cell Biology
The fission yeast plo1+ gene encodes a polo-like kinase, a member of a conserved family of kinases which play multiple roles during the cell cycle. We show that Plo1 kinase physically interacts with the anaphase-promoting complex (APC)/cyclosome thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c571a1519ae89462d98b1573d0695215
http://europepmc.org/articles/PMC2173567
http://europepmc.org/articles/PMC2173567
Publikováno v:
The Journal of Cell Biology
We describe a new Drosophila gene, mini spindles (msps) identified in a cytological screen for mitotic mutant. Mutation in msps disrupts the structural integrity of the mitotic spindle, resulting in the formation of one or more small additional spind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3ab4cd87bfc95ddc8b7e0e67a1d018
https://doi.org/10.1083/jcb.146.5.1005
https://doi.org/10.1083/jcb.146.5.1005
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001179 (2010)
PLoS Genetics
Lancaster, O M, Breuer, M, Cullen, C F, Ito, T & Ohkura, H 2010, ' The Meiotic Recombination Checkpoint Suppresses NHK-1 Kinase to Prevent Reorganisation of the Oocyte Nucleus in Drosophila ', PLoS Genetics, vol. 6, no. 10, e1001179, pp.-. https://doi.org/10.1371/journal.pgen.1001179
PLoS Genetics
Lancaster, O M, Breuer, M, Cullen, C F, Ito, T & Ohkura, H 2010, ' The Meiotic Recombination Checkpoint Suppresses NHK-1 Kinase to Prevent Reorganisation of the Oocyte Nucleus in Drosophila ', PLoS Genetics, vol. 6, no. 10, e1001179, pp.-. https://doi.org/10.1371/journal.pgen.1001179
The meiotic recombination checkpoint is a signalling pathway that blocks meiotic progression when the repair of DNA breaks formed during recombination is delayed. In comparison to the signalling pathway itself, however, the molecular targets of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86a206051ff7465e4bf53f43898fbc5
http://europepmc.org/articles/PMC2965759?pdf=render
http://europepmc.org/articles/PMC2965759?pdf=render
Akademický článek
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Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis
Autor:
Mar Carmena, Janet K. Jang, Hiroyuki Ohkura, Kim S. McKim, C. Fiona Cullen, Nathalie Colombié, William C. Earnshaw, Amy L. Brittle
Publikováno v:
Colombie, N, Cullen, F, Brittle, A, Jang, J, Earnshaw, B, Carmena, M, McKim, K & Ohkura, H 2008, ' Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis ', Development, vol. 135, no. 19, pp. 3239-3246 . https://doi.org/10.1242/dev.022624
Spindle formation in female meiosis differs from mitosis in many animals,as it takes place independently of centrosomes, and the molecular requirements of this pathway remain to be understood. Here, we report two crucial roles of Incenp, an essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7cb41ab9ff8dc8c288a97fb35a1e9e
https://pubmed.ncbi.nlm.nih.gov/18755775
https://pubmed.ncbi.nlm.nih.gov/18755775