Výsledky vyhledávání - "C. Erik Hack"

Akademický článek

Human IAPP is a contributor to painful diabetic peripheral neuropathy

Autor: Mohammed M.H. Albariqi, Sabine Versteeg, Elisabeth M. Brakkee, J. Henk Coert, Barend O.W. Elenbaas, Judith Prado, C. Erik Hack, Jo W.M. Höppener, Niels Eijkelkamp

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)

Peripheral neuropathy is a frequent complication of type 2 diabetes mellitus (T2DM). We investigated whether human islet amyloid polypeptide (hIAPP), which forms pathogenic aggregates that damage pancreatic islet β cells in T2DM, is involved in T2DM

Externí odkaz: https://doaj.org/article/0c6ff11c20e345b8ad647d87d76b2e1e

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Akademický článek

High occurrence of antihistamine resistance in patients with recurrent idiopathic angioedema

Autor: Zonne L. M. Hofman, Nikki van West, C. Erik Hack, André C. Knulst, Coen Maas, Heike Röckmann

Publikováno v: Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-5 (2019)

Abstract Antihistamines are the most prescribed therapy in recurrent idiopathic angioedema, yet little is known about their efficacy. Herein, we report on clinical improvement with antihistamine therapy in 120 patients evaluating angioedema attack fr

Externí odkaz: https://doaj.org/article/05daa0784378499689b97360569d48f6

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Akademický článek

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study

Autor: Kirsten van de Groep, Stefan Nierkens, Olaf L. Cremer, Linda M. Peelen, Peter M. C. Klein Klouwenberg, Marcus J. Schultz, C. Erik Hack, Tom van der Poll, Marc J. M. Bonten, David S. Y. Ong, on behalf of the MARS consortium

Publikováno v: Critical Care, Vol 22, Iss 1, Pp 1-9 (2018)

Abstract Background Cytomegalovirus (CMV) reactivation in previously immunocompetent critically ill patients is associated with increased mortality, which has been hypothesized to result from virus-induced immunomodulation. Therefore, we studied the

Externí odkaz: https://doaj.org/article/4a11f6e182a945c48db8acbb68bbdbb0

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Akademický článek

Quantification of neutralizing anti-drug antibodies and their neutralizing capacity using competitive displacement and tandem mass spectrometry: Infliximab as proof of principle

Autor: Mohsin El Amrani, Camiel Göbel, Annelies C. Egas, Stefan Nierkens, C. Erik Hack, Alwin D.R. Huitema, Erik M. van Maarseveen

Publikováno v: Journal of Translational Autoimmunity, Vol 1, Iss , Pp - (2019)

Background: The development of anti-drug antibodies (ADA) in patients treated with therapeutic proteins can result in treatment failure. The clinically most relevant fraction of these antibodies are the neutralizing anti-drug antibodies (NAb) that bl

Externí odkaz: https://doaj.org/article/233fb804500e42faa13ec88e51fbb4c0

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Akademický článek

The Autoimmune-Associated Single Nucleotide Polymorphism Within PTPN22 Correlates With Clinical Outcome After Lung Transplantation

Autor: Kevin Budding, Jessica van Setten, Eduard A. van de Graaf, Oliver A. van Rossum, Tineke Kardol-Hoefnagel, Johanna M. Kwakkel-van Erp, Erik-Jan D. Oudijk, C. Erik Hack, Henderikus G. Otten

Publikováno v: Frontiers in Immunology, Vol 9 (2019)

Obstructive chronic lung allograft dysfunction (BOS) is the major limiting factor for lung transplantation (LTx) outcome. PTPN22 is described as the hallmark autoimmunity gene, and one specific single nucleotide polymorphism (SNP), rs2476601, is asso

Externí odkaz: https://doaj.org/article/66bf25cf89784506a742cc981965ac8b

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Akademický článek

Autor: Kirsten Geneugelijk, Matthias Niemann, Julia Drylewicz, Arjan D. van Zuilen, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, C. Erik Hack, Franka E. van Reekum, Marianne C. Verhaar, Elena G. Kamburova, Michiel L. Bots, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Joris Vanderlocht, Christien E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Azam Nurmohamed, Junior N. M. Lardy, Wendy Swelsen, Karlijn A. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Fréderike J. Bemelman, Andries Hoitsma, Paul J. M. van der Boog, Johan W. de Fijter, Michiel G. H. Betjes, Sebastiaan Heidt, Dave L. Roelen, Frans H. Claas, Henny G. Otten, Eric Spierings

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Individual HLA mismatches may differentially impact graft survival after kidney transplantation. Therefore, there is a need for a reliable tool to define permissible HLA mismatches in kidney transplantation. We previously demonstrated that donor-deri

Externí odkaz: https://doaj.org/article/dfbc004143624e37972462011bc75b2a

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Akademický článek

Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation

Autor: Kevin Budding, Jessica van Setten, Eduard A. van de Graaf, Oliver A. van Rossum, Tineke Kardol-Hoefnagel, Erik-Jan D. Oudijk, C. Erik Hack, Henderikus G. Otten

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Lung transplantation (LTx) outcome is hampered by development of chronic rejection, often manifested as the bronchiolitis obliterans syndrome (BOS). Low serum levels of thymus and activation-regulated chemokine (TARC/CCL17), a chemoattractant, measur

Externí odkaz: https://doaj.org/article/bdeed6ac8b31494c9ed8885be5224f57

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