Zobrazeno 1 - 10
of 32 727
pro vyhledávání: '"C. Elegans"'
Autor:
Luca Golinelli, Ellen Geens, Allister Irvine, Ciaran J. McCoy, Elke Vandewyer, Louise E. Atkinson, Angela Mousley, Liesbet Temmerman, Isabel Beets
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background The phylum Nematoda is incredibly diverse and includes many parasites of humans, livestock, and plants. Peptide-activated G protein-coupled receptors (GPCRs) are central to the regulation of physiology and numerous behaviors, and
Externí odkaz:
https://doaj.org/article/c2d670455c1b439c9fcacc8998ab993e
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-10 (2024)
ABSTRACTTransgene silencing is a common phenomenon observed in Caenorhabditis elegans, particularly in the germline, but the precise mechanisms underlying this process remain elusive. Through an analysis of the transcription factors profile of C. ele
Externí odkaz:
https://doaj.org/article/c149a1698de14bbba6bd5cd90d2e12ae
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract 2K4L is a rationally designed analog of the short α-helical peptide temporin-1CEc, a natural peptide isolated and purified from the skin secretions of the Chinese brown frog Rana chensinensis by substituting amino acid residues. 2K4L displa
Externí odkaz:
https://doaj.org/article/3e302973277b434dbee0bc1785959e39
Autor:
Wenfeng Li, Shuming Chen, Jing Lang, Jing Luo, Jiahui Chen, Liping Zhang, Zhijie Sun, Deli Dong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3266-3280 (2024)
The drugs extending healthspan in clinic have always been searched. Nitazoxanide is an FDA-approved clinical antiprotozoal drug. Nitazoxanide is rapidly metabolized to tizoxanide after absorption in vivo. Our previous studies find that nitazoxanide a
Externí odkaz:
https://doaj.org/article/a97e426a84d445f1b4e36333464de582
Autor:
Calabrese Vittorio, Wenzel Uwe, Piccoli Tommaso, Jacob Ursula M., Nicolosi Lidia, Fazzolari Giovanni, Failla Gabriella, Fritsch Tilman, Osakabe Naomi, Calabrese Edward J.
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 376-97 (2024)
Mitochondria-derived reactive oxygen species production at a moderate physiological level plays a fundamental role in the anti-aging signaling, due to their action as redox-active sensors for the maintenance of optimal mitochondrial balance between i
Externí odkaz:
https://doaj.org/article/544acd620ffc4832928b7acde9e5f14d
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 286, Iss , Pp 117226- (2024)
6-PPD quinone (6-PPDQ) is extensively existed in various environments. In Caenorhabditis elegans, exposure to 6-PPDQ could cause multiple toxic effects. In the current study, we further used C. elegans to investigate the effect of paeoniflorin (PF) t
Externí odkaz:
https://doaj.org/article/edb61525415b4bd8b33ceb5baabd1de9
Autor:
Malaimegu Subhadra, Dilawar Ahmad Mir, Koley Ankita, Muthukrishnan Sindunathy, Hambram David Kishore, Velayutham Ravichandiran, Krishnaswamy Balamurugan
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionDiabesity, characterized by obesity-driven Type 2 diabetes mellitus (T2DM), arises from intricate genetic and environmental interplays that induce various metabolic disorders. The systemic lipid and glucose homeostasis is controlled by an
Externí odkaz:
https://doaj.org/article/2c0635fc5258455b84af4fd9882aaa7a
Autor:
Seunghyun Kim, Yu-Ri Lee, Haneol Yang, Chan-Hyeok Park, Chan-Seok Yun, Byung-Chun Jang, Yeongjin Hong, Doo-Sang Park
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Probiotics are live microorganisms that provide health benefits when administered in appropriate amounts by improving or restoring the balance of intestinal microbiota. Various functional probiotic products have been developed due to the growing inte
Externí odkaz:
https://doaj.org/article/cbe3cf93e84a4f6fbfa26160ce26e594