Zobrazeno 1 - 10
of 545
pro vyhledávání: '"C. Earnshaw"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Multiple microtubule-directed activities concentrate on mitotic chromosomes to ensure their faithful segregation. These include couplers and dynamics regulators localized at the kinetochore, the microtubule interface built on centromeric chr
Externí odkaz:
https://doaj.org/article/9194aac344124d20b7a3b93d51bd888c
Autor:
Natalia Y. Kochanova, Petra Vizjak, Maria Alba Abad, William C. Earnshaw, A. Arockia Jeyaprakash, Georg Kustatscher
Publikováno v:
Wellcome Open Research, Vol 8 (2024)
Background Unicorn™ software on Äkta liquid chromatography instruments outputs chromatography profiles of purified biological macromolecules. While the plots generated by the instrument software are very helpful to inspect basic chromatogram prope
Externí odkaz:
https://doaj.org/article/ee935080b91b48e3bb133dcad9ca0ad1
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/0c0c030dc1c54c61a794787a99cca008
Autor:
Natalia Y. Kochanova, Petra Vizjak, Maria Alba Abad, William C. Earnshaw, A. Arockia Jeyaprakash, Georg Kustatscher
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Background: UnicornTM software on Äkta liquid chromatography instruments outputs chromatography profiles of purified biological macromolecules. While the plots generated by the instrument software are very helpful to inspect basic chromatogram prope
Externí odkaz:
https://doaj.org/article/e04a79c7246140bdb577940e882246dc
Autor:
Lucy Remnant, Natalia Y. Kochanova, Caitlin Reid, Fernanda Cisneros-Soberanis, William C. Earnshaw
Publikováno v:
Open Biology, Vol 11, Iss 8 (2021)
Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review some of the current literature regarding the protein. Despite
Externí odkaz:
https://doaj.org/article/35ca6220cccf483eae229c9aafbdb243
Autor:
Koei Okazaki, Megumi Nakano, Jun-ichirou Ohzeki, Koichiro Otake, Kazuto Kugou, Vladimir Larionov, William C. Earnshaw, Hiroshi Masumoto
Publikováno v:
Cells, Vol 11, Iss 9, p 1378 (2022)
Human artificial chromosomes (HACs) can be formed de novo by introducing large (>30 kb) centromeric sequences consisting of highly repeated 171-bp alpha satellite (alphoid) DNA into HT1080 cells. However, only a subset of transformed cells successful
Externí odkaz:
https://doaj.org/article/7ed9bd2928dc495dbaf0357bfe984312
Autor:
Lora Boteva, Ryu-Suke Nozawa, Catherine Naughton, Kumiko Samejima, William C. Earnshaw, Nick Gilbert
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108177- (2020)
Summary: Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer
Externí odkaz:
https://doaj.org/article/bd191e3aabbf4a60bf450f5a8d71b639
Autor:
Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond, Su Chu, Alan R. Healy, Gergana Popova, Andrés Pastor Fernández, Tanzina Mollick, Suhas Darekar, Saikiran K. Sedimbi, Marta Nekulova, Marijke C. C. Sachweh, Johanna Campbell, Maureen Higgins, Chloe Tuck, Mihaela Popa, Mireia Mayoral Safont, Pascal Gelebart, Zinayida Fandalyuk, Alastair M. Thompson, Richard Svensson, Anna-Lena Gustavsson, Lars Johansson, Katarina Färnegårdh, Ulrika Yngve, Aljona Saleh, Martin Haraldsson, Agathe C. A. D’Hollander, Marcela Franco, Yan Zhao, Maria Håkansson, Björn Walse, Karin Larsson, Emma M. Peat, Vicent Pelechano, John Lunec, Borivoj Vojtesek, Mar Carmena, William C. Earnshaw, Anna R. McCarthy, Nicholas J. Westwood, Marie Arsenian-Henriksson, David P. Lane, Ravi Bhatia, Emmet McCormack, Sonia Laín
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract The development of non-genotoxic therapies that activate wild-type p53 in tumors is of great interest since the discovery of p53 as a tumor suppressor. Here we report the identification of over 100 small-molecules activating p53 in cells. We
Externí odkaz:
https://doaj.org/article/c70bab1df6ec4076bb2c93aa455abeeb
Autor:
Raeann M. Dalton, Young Son, Brian M. Thomas, Abdullah Junayed, Megan E. Donlick, Kathryn P. Goettle, Lance C. Earnshaw, Wei Jiang, Wilbur Bowne, Thomas J. Mueller
Publikováno v:
The Korean Journal of Urological Oncology. 20:273-277
Liposarcomas of the spermatic cord are rare and often clinically and histologically misdiagnosed, leading to ineffective management and poor outcomes. We present a case of metastatic dedifferentiated liposarcoma of the spermatic cord, which recurred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9085060eaaffceae34337a9cd7c8b7ad
https://doi.org/10.22465/kjuo.2022.20.4.273
https://doi.org/10.22465/kjuo.2022.20.4.273
Autor:
Mikhail Liskovykh, Nikolai S. Petrov, Vladimir N. Noskov, Hiroshi Masumoto, William C. Earnshaw, David Schlessinger, Svetlana A. Shabalina, Vladimir Larionov, Natalay Kouprina
Publikováno v:
Liskovykh, M, Petrov, N S, Noskov, V N, Masumoto, H, Earnshaw, W C, Schlessinger, D, Shabalina, S A, Larionov, V & Kouprina, N 2023, ' Actively transcribed rDNA and distal junction (DJ) sequence are involved in association of NORs with nucleoli ', Cellular and Molecular Life Sciences, vol. 80, no. 5, 121 . https://doi.org/10.1007/s00018-023-04770-3
Although they are organelles without a limiting membrane, nucleoli have an exclusive structure, built upon the rDNA-rich acrocentric short arms of five human chromosomes (nucleolar organizer regions or NORs). This has raised the question: what are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c6d0a17bc08a5f209032b9cf607d0c
https://hdl.handle.net/20.500.11820/bf60b92a-f13e-4419-90da-6aaf6adb3a3a
https://hdl.handle.net/20.500.11820/bf60b92a-f13e-4419-90da-6aaf6adb3a3a
