Zobrazeno 1 - 10
of 19
pro vyhledávání: '"C. E. Smithen"'
Publikováno v:
Radiation research. 178(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfe016287b35de0ebcf5b796758e9c90
https://pubmed.ncbi.nlm.nih.gov/22870968
https://pubmed.ncbi.nlm.nih.gov/22870968
Autor:
D Bradshaw, C R Self, J C Wickens, D. P. Bloxham, Peter James Machin, C H Cashin, B P Tong, W E Barber, C E Smithen, John Mervyn Osbond
Publikováno v:
Journal of Medicinal Chemistry. 34:772-777
The synthesis of a series of substituted heterocyclic alkoxypropionic acids is described. They were evaluated for antiinflammatory effects in two animal models of chronic inflammation; adjuvant arthritis and type II collagen arthritis in the rat. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dbaf20a951916425ef40322324f05e
https://doi.org/10.1021/jm00106a044
https://doi.org/10.1021/jm00106a044
Autor:
Barry D. Michael, Andrew I. Minchinton, Juliana Denekamp, N H Terry, Michael R.L. Stratford, F.A. Stewart, C E Smithen
Publikováno v:
British Journal of Cancer
The survival of epidermal cells in vivo has been used to assess potential radiosensitizers. Mouse skin was made acutely hypoxic for the irradiations, to give radioprotection by a factor of 2.7-3.0. Several concentrations of each drug were used to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1670d3fc33341a2ae6dc6eebde167177
https://doi.org/10.1038/bjc.1982.40
https://doi.org/10.1038/bjc.1982.40
Publikováno v:
Radiation research. 60(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e2d17daddc30d471d235516fbaba02f
https://pubmed.ncbi.nlm.nih.gov/10881704
https://pubmed.ncbi.nlm.nih.gov/10881704
Autor:
C. R. Hardy, C. E. Smithen
Publikováno v:
Advanced Topics on Radiosensitizers of Hypoxic Cells ISBN: 9781475704013
It is now well recognised that the imidazole ring system is an important component of many different types of natural products having a wide range of biological activities, including those essential for life itself. For example, in the form of the am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc1bbdcb2854ae11f132129ffaa2070
https://doi.org/10.1007/978-1-4757-0399-3_1
https://doi.org/10.1007/978-1-4757-0399-3_1
Publikováno v:
Radiation research. 101(1)
Bothtrans-N,N'-bis(2,2,6,6-tetramethyl-1-oxyl-4-piperidinyl)-1, 2-diaminocyclopropane[Ro31-2269] and its cis isomer [Ro 31-2778] selectively sensitized hypoxic Chinese hamster cells, line V-79-753B, to radiation by decreasing both the D0 value and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08817f6aeb2a4e09f35445c97b80f1d7
https://pubmed.ncbi.nlm.nih.gov/3969438
https://pubmed.ncbi.nlm.nih.gov/3969438
Publikováno v:
The British journal of cancer. Supplement. 3
The two nitropyridinium compounds tested sensitize hypoxic Serratia marcescens to irradiation up to the oxygen enhancement level by two components which can be separated as a function of compound concentration. Sensitization above the initial plateau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fb6465fdd0a6e759878318d063a9f65
https://pubmed.ncbi.nlm.nih.gov/354674
https://pubmed.ncbi.nlm.nih.gov/354674
Publikováno v:
Radiation research. 67(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80c30c5e637f22279ae5f609ff3ae079
https://pubmed.ncbi.nlm.nih.gov/940937
https://pubmed.ncbi.nlm.nih.gov/940937
Publikováno v:
The British journal of cancer. Supplement. 3
Three biradical nitroxyl compounds have been shown to modify the slope and shoulder region of the hypoxic cell survival curve of V79 cells to different degrees. The amount of sensitization produced by these compounds is dependent on the cell-drug con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::576d0637f4546b4cc26e6e11a4e17305
https://pubmed.ncbi.nlm.nih.gov/277261
https://pubmed.ncbi.nlm.nih.gov/277261