Výsledky vyhledávání

A Protein Interaction Map of Drosophila melanogaster

Publikováno v: Science. 302:1727-1736

Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid–based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587ee6152a0503c63f3d9160ee3a36e4
https://doi.org/10.1126/science.1090289

Zobrazit plný text záznamu

Plný text ve formátu HTML

Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis

Autor: C E, Ooi, E, Rabinovich, A, Dancis, J S, Bonifacino, R D, Klausner

Publikováno v: The EMBO journal. 15(14)

The cell surface protein repertoire needs to be regulated in response to changes in the extracellular environment. In this study, we investigate protein turnover of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p, in response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc0fef4496ab16f0b90a3892b08b32f5
https://pubmed.ncbi.nlm.nih.gov/8670854

Zobrazit plný text záznamu

Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins

Autor: O, Levy, C E, Ooi, P, Elsbach, M E, Doerfler, R I, Lehrer, J, Weiss

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 154(10)

Bactericidal/permeability-increasing protein (BPI), antibacterial 15-kDa protein isoforms (p15s), and defensins (neutrophil peptides or NPs) are granule-associated antibacterial proteins of polymorphonuclear leukocytes (PMN) that have both direct and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5ace967949cd98f071ef8b7d8cc1994
https://pubmed.ncbi.nlm.nih.gov/7730641

Zobrazit plný text záznamu

A phase I/II study of CR011-vcMMAE, an antibody toxin conjugate drug, in patients with unresectable stage III/IV melanoma

Autor: C. E. Ooi, Nicholas E. Papadopoulos, H. Kluger, Peter D. Boasberg, L. Rink, D. Sanders, Omid Hamid, M. Sznol, Patrick Hwu, K. B. Kim

Publikováno v: Journal of Clinical Oncology. 26:9029-9029

9029 Background: Glycoprotein NMB (GPNMB) is highly expressed in melanoma. CR011-vcMMAE is comprised of a human monoclonal antibody against the extracellular domain of GPNMB conjugated to the micro...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cb9615940933f241a84bccb247c9a816
https://doi.org/10.1200/jco.2008.26.15_suppl.9029

Zobrazit plný text záznamu

Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate

Autor: G W, Wright, C E, Ooi, J, Weiss, P, Elsbach

Publikováno v: The Journal of biological chemistry. 265(12)

A granule-associated phospholipase A2 from rabbit polymorphonuclear leukocytes and a closely similar phospholipase A2 from rabbit serum have been purified to near homogeneity by ion-exchange and reverse-phase chromatography. The cellular (polymorphon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4cfb36c94a555f682b7c0b7984b0e25f
https://pubmed.ncbi.nlm.nih.gov/2182625

Zobrazit plný text záznamu

A phase Ib/II study of PXD101 alone and in combination with 5-fluorouracil in patients with advanced solid tumors

Autor: Donald W. Northfelt, Eric M. Bonnem, C. E. Ooi, Thomas Hawthorne, J. Grem, A. Clarke, D. D. Von Hoff, R. Gerwien, Robert F. Marschke, P. Buhl-Jensen

Publikováno v: Journal of Clinical Oncology. 25:3501-3501

3501 Background: PXD101 is a hydroxamate HDAC inhibitor that has broad anti-neoplastic activity in vivo and in vitro. Preclinical data showing PXD101 down-regulation of thymidylate synthase (TS), an in vivo target of 5-fluorouracil (5-FU) provide a r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::592d549b9943bb9b3d7908f9f78bd7a5
https://doi.org/10.1200/jco.2007.25.18_suppl.3501

Zobrazit plný text záznamu

181 POSTER A Phase Ib safety and pharmacodynamic study of PXD101 alone and in combination with 5-fluorouracil in patients with advanced solid tumors

Autor: T. Hawthorne, C. E. Ooi, Donald W. Northfelt, P. Buhl-Jensen, R. Gerwien, J. Grem, Gladys Rodriguez, D. D. Von Hoff, A. Clarke, Siân Jones

Publikováno v: European Journal of Cancer Supplements. 4:57

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73d332095b2495ed935b61be36ed8528
https://doi.org/10.1016/s1359-6349(06)70186-0

Zobrazit plný text záznamu

Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

Autor: P W, Gray, G, Flaggs, S R, Leong, R J, Gumina, J, Weiss, C E, Ooi, P, Elsbach

Publikováno v: The Journal of biological chemistry. 264(16)

The bactericidal permeability increasing protein (BPI) is a 50-60-kDa membrane-associated protein isolated from granules of polymorphonuclear leukocytes. A full-length cDNA clone encoding human BPI has been isolated and the derived amino acid sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a6393aba684e38819a49d2f0a8a73a3
https://pubmed.ncbi.nlm.nih.gov/2722846

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání