Sphingolipids in Inflammation: Roles and Implications

Autor: Yusuf A. Hannun, C. E. Chalfant, Benjamin J. Pettus

Publikováno v: Current Molecular Medicine. 4:405-418

Sphingolipids, historically described as potential reservoirs for bioactive lipids, presently define a new family of cellular mediators, joining the well-established glycerolipid-derived mediators of signal transduction such as diacylglycerol, phosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038e6bb94b6e845a0103ef5fd0d4f2b1
https://doi.org/10.2174/1566524043360573

Analysis of ceramide-activated protein phosphatases

Autor: C E, Chalfant, K, Kishikawa, A, Bielawska, Y A, Hannun

Publikováno v: Methods in enzymology. 312

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ecd7dd5ca566b9c67070f29f6e11e8c0
https://pubmed.ncbi.nlm.nih.gov/11070890

Ectopic expression of protein kinase CbetaII, -delta, and -epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose uptake in NIH-3T3 cells

Autor: D R, Cooper, J E, Watson, N, Patel, P, Illingworth, M, Acevedo-Duncan, J, Goodnight, C E, Chalfant, H, Mischak

Publikováno v: Archives of biochemistry and biophysics. 372(1)

Insulin regulates a diverse array of signaling pathways involved in the control of growth, differentiation, proliferation, and metabolism. Insulin increases in glucose uptake via a protein kinase C-dependent pathway in target tissues such as fat and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2d2c5457417a154213f37e1c7429f06
https://pubmed.ncbi.nlm.nih.gov/10562418

Insulin regulates protein kinase CbetaII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-i-induced 5' splice site selection

Autor: C E, Chalfant, J E, Watson, L D, Bisnauth, J B, Kang, N, Patel, L M, Obeid, D C, Eichler, D R, Cooper

Publikováno v: The Journal of biological chemistry. 273(2)

The protein kinase Cbeta (PKCbeta) gene encodes two isoforms, PKCbetaI and PKCbetaII, as a result of alternative splicing. The unique mechanism that underlies insulin-induced alternative splicing of PKCbeta pre-mRNA was examined in L6 myotubes. Matur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c85f2b9eceb4f30d06327351bb5af648
https://pubmed.ncbi.nlm.nih.gov/9422749

Purification of Cytosolic Phospholipase A 2 α C2-domain after Expression in Soluble Form in Escherichia coli .

Autor: Hirano Y; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, U.S.A.; Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST), Takayama, Japan., Gao YG; Hormel Institute, University of Minnesota, Austin, MN, U.S.A., K Simanshu D; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, U.S.A., J Stephenson D; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University Medical Center, Richmond, VA, U.S.A.; Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, U.S.A., T Vu N; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University Medical Center, Richmond, VA, U.S.A., Malinina L; Hormel Institute, University of Minnesota, Austin, MN, U.S.A., E Chalfant C; Department of Biochemistry and Molecular Biology, Virginia Commonwealth University Medical Center, Richmond, VA, U.S.A.; Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, FL, U.S.A.; Research Service, James A. Haley Veterans Hospital, Tampa, FL, U.S.A.; The Moffitt Cancer Center, Tampa, FL, U.S.A., J Patel D; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, U.S.A., E Brown R; Hormel Institute, University of Minnesota, Austin, MN, U.S.A.

Publikováno v: Bio-protocol [Bio Protoc] 2021 Feb 05; Vol. 11 (3), pp. e3906. Date of Electronic Publication: 2021 Feb 05 (Print Publication: 2021).