Zobrazeno 1 - 10 of 149 pro vyhledávání: '"C. E. Chalfant"'
2
Sphingolipids in Inflammation: Roles and Implications
Autor: Yusuf A. Hannun, C. E. Chalfant, Benjamin J. Pettus
Publikováno v: Current Molecular Medicine. 4:405-418
Sphingolipids, historically described as potential reservoirs for bioactive lipids, presently define a new family of cellular mediators, joining the well-established glycerolipid-derived mediators of signal transduction such as diacylglycerol, phosph
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038e6bb94b6e845a0103ef5fd0d4f2b1
https://doi.org/10.2174/1566524043360573
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3
FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1
Autor: C E, Chalfant, B, Ogretmen, S, Galadari, B J, Kroesen, B J, Pettus, Y A, Hannun
Publikováno v: The Journal of biological chemistry. 276(48)
The search for potential targets for ceramide action led to the identification of ceramide-activated protein phosphatases (CAPP). To date, two serine/threonine protein phosphatases, protein phosphatase 2A (PP2A) and protein phosphatase 1 (PP1), have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75d9749e21af0b511c6b73027a3898b6
https://pubmed.ncbi.nlm.nih.gov/11502750
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5
Protein kinase Ctheta expression is increased upon differentiation of human skeletal muscle cells: dysregulation in type 2 diabetic patients and a possible role for protein kinase Ctheta in insulin-stimulated glycogen synthase activity
Autor: C E, Chalfant, T P, Ciaraldi, J E, Watson, S, Nikoulina, R R, Henry, D R, Cooper
Publikováno v: Endocrinology. 141(8)
Protein kinase C (PKCtheta) is a key enzyme in regulating a variety of cellular functions, including growth and differentiation. PKCtheta is the most abundant PKC isoform expressed in skeletal muscle; however, its role in differentiation and metaboli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8af290934b8b208a8a016df260be5cf
https://pubmed.ncbi.nlm.nih.gov/10919262
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6
Ectopic expression of protein kinase CbetaII, -delta, and -epsilon, but not -betaI or -zeta, provide for insulin stimulation of glucose uptake in NIH-3T3 cells
Autor: D R, Cooper, J E, Watson, N, Patel, P, Illingworth, M, Acevedo-Duncan, J, Goodnight, C E, Chalfant, H, Mischak
Publikováno v: Archives of biochemistry and biophysics. 372(1)
Insulin regulates a diverse array of signaling pathways involved in the control of growth, differentiation, proliferation, and metabolism. Insulin increases in glucose uptake via a protein kinase C-dependent pathway in target tissues such as fat and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2d2c5457417a154213f37e1c7429f06
https://pubmed.ncbi.nlm.nih.gov/10562418
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7
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid
Autor: C E, Chalfant, K, Kishikawa, M C, Mumby, C, Kamibayashi, A, Bielawska, Y A, Hannun
Publikováno v: The Journal of biological chemistry. 274(29)
The search for potential targets for ceramide action led to the identification of ceramide-activated protein phosphatases, which include protein phosphatase-2A (PP2A) and protein phosphatase-1 (PP1) with roles in regulating apoptosis and cell growth.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9db5e0f13f68b26f03c45d74965363cd
https://pubmed.ncbi.nlm.nih.gov/10400653
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8
Insulin regulates protein kinase CbetaII expression through enhanced exon inclusion in L6 skeletal muscle cells. A novel mechanism of insulin- and insulin-like growth factor-i-induced 5' splice site selection
Autor: C E, Chalfant, J E, Watson, L D, Bisnauth, J B, Kang, N, Patel, L M, Obeid, D C, Eichler, D R, Cooper
Publikováno v: The Journal of biological chemistry. 273(2)
The protein kinase Cbeta (PKCbeta) gene encodes two isoforms, PKCbetaI and PKCbetaII, as a result of alternative splicing. The unique mechanism that underlies insulin-induced alternative splicing of PKCbeta pre-mRNA was examined in L6 myotubes. Matur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c85f2b9eceb4f30d06327351bb5af648
https://pubmed.ncbi.nlm.nih.gov/9422749
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9
Akademický článek
Innovative Bio‐based Hydrogel Microspheres Micro‐Cage for Neutrophil Extracellular Traps Scavenging in Diabetic Wound Healing.
Autor: Xiao, Yongqiang1 (AUTHOR), Ding, Tao2 (AUTHOR), Fang, He3 (AUTHOR), Lin, Jiawei1 (AUTHOR), Chen, Lili1 (AUTHOR), Ma, Duan4 (AUTHOR), Zhang, Tianyu1 (AUTHOR) ty_zhang@fudan.edu.cn, Cui, Wenguo2 (AUTHOR) wgcui@sjtu.edu.cn, Ma, Jing1 (AUTHOR) maj14@fudan.edu.cn
Publikováno v: Advanced Science. 6/5/2024, Vol. 11 Issue 21, p1-16. 16p.
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10
Akademický článek
Splicing Factor PQBP1 Curtails BAX Expression to Promote Ovarian Cancer Progression.
Autor: Liu, Xihan1,2 (AUTHOR), Zhang, Jiaojiao1 (AUTHOR), Wang, Zixiang1,2 (AUTHOR), Yan, Mingyao1 (AUTHOR), Xu, Meining1 (AUTHOR), Li, Gaoyuan1 (AUTHOR), Shender, Victoria3 (AUTHOR), Wei, Jian‐jun4 (AUTHOR), Li, Jianqiao5 (AUTHOR), Shao, Changshun6 (AUTHOR), Zhang, Shiqian1 (AUTHOR), Kong, Beihua1 (AUTHOR), Song, Kun1 (AUTHOR) songkun2001226@sdu.edu.cn, Liu, Zhaojian1,2 (AUTHOR) liujian9782@sdu.edu.cn
Publikováno v: Advanced Science. 4/17/2024, Vol. 11 Issue 15, p1-14. 14p.
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