Výsledky vyhledávání - "C. E. Calkins"

Expression and regulation of a recurrent anti-erythrocyte autoantibody idiotype in spleen cells from neonatal and adult BALB/c mice

Autor: R D, Miller, M J, Caulfield, C E, Calkins

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 148(8)

BALB/c spleen cells depleted of CD8+ T cells generate an autoantibody response to mouse RBC (MRBC) when cultured 5 days in the presence of syngeneic RBC. More than 80% of the cells secreting anti-MRBC antibody are blocked by an antiidiotypic mAb that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a83dfd45ac8cec77861b8f3c6b3f6a42
https://pubmed.ncbi.nlm.nih.gov/1560201

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Maintenance and cure of the L5178Y murine tumor-dormant state by interleukin 2: in vivo and in vitro effects

Autor: C M, Liu, Y, Suzuki, L P, Chen, T, Okayasu, C E, Calkins, E F, Wheelock

Publikováno v: Cancer research. 50(5)

We studied the antitumor effects of recombinant human interleukin 2 (HuIL-2) in DBA/2 mice which harbor L5178Y lymphoma cells in a tumor-dormant state in the peritoneal cavity and in peritoneal cell (PC) cultures prepared from such mice. Intraperiton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76f7b8949b378fec25d6a05e41e86ed0
https://pubmed.ncbi.nlm.nih.gov/2302701

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Suppressor T cells and self-tolerance. Active suppression required for normal regulation of anti-erythrocyte autoantibody responses in spleen cells from nonautoimmune mice

Autor: R D Miller, C E Calkins

Publikováno v: The Journal of Immunology. 140:3779-3785

Spleen cells from young, nonautoimmune strains of mice cultured with syngeneic E do not develop a significant anti-mouse E response in vitro, consistent with a state of self-tolerance to this Ag. In order to study the role of active suppression in re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e88ed57b66aa7c6b5a52ae8093976ca
https://doi.org/10.4049/jimmunol.140.11.3779

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Changes in suppressor mechanisms during postnatal development in mice

Autor: C E Calkins, O Stutman

Publikováno v: The Journal of Experimental Medicine

The activity of suppressor cells from spleens of mice of varying ages was assessed by their addition to cultures of normal or SRBC immune spleen cells together with a challenge of SRBC. 1-wk and adult spleen cells were highly suppressive of the secon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03b1a7a640a2998a0ea431132195743
https://doi.org/10.1084/jem.147.1.87

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Evidence for interaction between T cell populations of tumor-bearing and normal mice in immune suppression

Autor: G G Ingenito, C E Calkins

Publikováno v: The Journal of Immunology. 127:1236-1240

Spleen cells of DBA/2 mice bearing subcutaneous implants of the syngeneic tumor L5178Y induce suppression of the in vitro antibody response of normal spleen cells to sheep erythrocytes (SRBC). Cells mediating suppression are detected in the spleens o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29b93d1c31ceff75a6c9e62849378b8f
https://doi.org/10.4049/jimmunol.127.3.1236

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In vitro regulation of the pathogenic autoantibody response of New Zealand black mice. I. Loss with age of suppressive activity in T cell populations

Autor: J S Moore, C E Calkins

Publikováno v: The Journal of Immunology. 134:3838-3844

An investigation of the regulation of specific anti-self responses was initiated with the development of an in vitro system in which spleen cells from NZB mice were stimulated by syngeneic mouse erythrocytes (MRBC) to produce MRBC-specific autoantibo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af05da41576483baabe602e1adebd77
https://doi.org/10.4049/jimmunol.134.6.3838

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Development of self-tolerance in normal mice. Appearance of suppressor cells that maintain adult self-tolerance follows the neonatal autoantibody response

Autor: R D Miller, C E Calkins

Publikováno v: The Journal of Immunology. 141:2206-2210

T cell populations from BALB/c mice at different ages were analyzed to determine when in development Ts cells specific for the anti-mouse RBC (MRBC) autoantibody response become activated. Previous studies have shown that adult CD8+ T cells actively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::546f9da2eae566d7abc9cd830f0a2adb
https://doi.org/10.4049/jimmunol.141.7.2206

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B cells in the appendix and other lymphoid organs of the rabbit: complement receptor lymphocytes

Autor: C E, Calkins, J M, Carboni, B H, Waksman

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 115(5)

Complement receptor lymphocytes were demonstrated in rabbit lymphoid organs, the spleen containing the highest numbers (35%) and the thymus none. Extremely variable numbers (up to 50%) were detectablein the appendix. B and T cell depletion, rosette d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a1f4601618cff66fbf5bb7367bf492c
https://pubmed.ncbi.nlm.nih.gov/1080779

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Development of self-tolerance in normal mice. Appearance of suppressor cells that maintain adult self-tolerance follows the neonatal autoantibody response

Autor: R D, Miller, C E, Calkins

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 141(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff3f7b11967ca3bdb0720bdd1996cc9e
https://pubmed.ncbi.nlm.nih.gov/2902137

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