Zobrazeno 1 - 10
of 42
pro vyhledávání: '"C. E. Brinckerhoff"'
Autor:
C E Brinckerhoff, C A Whipple
Publikováno v:
British Journal of Cancer
Background: Melanoma, the most lethal form of skin cancer, is responsible for over 80% of all skin cancer deaths and is highly metastatic, readily spreading to the lymph nodes or metastasising to other organs. The frequent genetic mutation found in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d425b213a2878afbd21e28e8bcd9264
http://europepmc.org/articles/PMC4200092
http://europepmc.org/articles/PMC4200092
Publikováno v:
Scandinavian Journal of Immunology. 46:284-291
Serum amyloid A apolipoproteins (apoSAA) appear to compromise the ability of high density lipoprotein to protect against atherosclerosis and it is of interest to determine whether aortic smooth muscle cells can contribute to local pools of apoSAA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0aa380f0192a73cb458af8a1f92b73
https://doi.org/10.1046/j.1365-3083.1997.d01-128.x
https://doi.org/10.1046/j.1365-3083.1997.d01-128.x
Autor:
Donald K. Scott, C O Quinn, J J Jeffrey, C E Brinckerhoff, Nicola C. Partridge, L M Matrisian
Publikováno v:
Journal of Biological Chemistry. 265:22342-22347
We have isolated clones for rat collagenase from a rat osteoblastic cell cDNA library. These clones have been sequenced and the amino acids deduced. The calculated molecular weight is 51,352 for the proenzyme and 42,229 for the active enzyme. The ded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f24be4909048b7a0dbd32c0f475d413
https://doi.org/10.1016/s0021-9258(18)45711-0
https://doi.org/10.1016/s0021-9258(18)45711-0
Autor:
J B, Catterall, S, Carrère, P J, Koshy, B A, Degnan, W D, Shingleton, C E, Brinckerhoff, J, Rutter, T E, Cawston, A D, Rowan
Publikováno v:
Arthritis and rheumatism. 44(10)
To investigate the mechanism of interleukin-1alpha (IL-1alpha) and oncostatin M (OSM) synergistic regulation of matrix metalloproteinase 1 (MMP-1) in human chondrocytes.Using an immortalized human chondrocyte cell line (T/C28a4), we investigated regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1572c72223ddf859d11deac71dbc89d
https://pubmed.ncbi.nlm.nih.gov/11665970
https://pubmed.ncbi.nlm.nih.gov/11665970
Publikováno v:
Arthritis and rheumatism. 44(5)
To address the effects of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), on the induction of matrix metalloproteinases 1 and 13 (MMP-1, MMP-13) by inflammatory cytokines.Human chondrosarcoma cells stimulated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56f3b7826e130505064b758180d15842
https://pubmed.ncbi.nlm.nih.gov/11352241
https://pubmed.ncbi.nlm.nih.gov/11352241
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(12)
Degradation of the extracellular matrix is the sine qua non of tumor invasion and metastasis. Most of this degradation is mediated by matrix metalloproteinases (MMPs), a family of enzymes that, collectively, degrades the extracellular matrix. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8d6373977a4a33c01f35f1ebd6f9ef6
https://pubmed.ncbi.nlm.nih.gov/11156241
https://pubmed.ncbi.nlm.nih.gov/11156241
Publikováno v:
Cytometry. 40(4)
Most assays used to measure invasion are based on manual counting of the number of cells that have migrated completely through commercial coated filters. We describe here a confocal fluorescence-imaging method that can assess the relative rates of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8deeef546be38f8d09eeb67bda9a2be8
https://pubmed.ncbi.nlm.nih.gov/10918276
https://pubmed.ncbi.nlm.nih.gov/10918276
Publikováno v:
Clinicalexperimental metastasis. 17(3)
Matrix metalloproteinases (MMPs) play an important role in tumor cell invasion and metastasis. These processes require the dissolution of the basement membrane and invasion of the stromal matrix (ECM), and are mediated by MMPs. Consequently, MMP inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81504e1e5572a6f5567734e5dbdfb66e
https://pubmed.ncbi.nlm.nih.gov/10432008
https://pubmed.ncbi.nlm.nih.gov/10432008
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(1)
Matrix metalloproteinases (MMPs) play a crucial role in tumor cell invasion and metastasis due to their ability to digest basement membrane and extracellular matrix components, thereby facilitating cell movement through connective tissues. At noncyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3abcd41f997299f0fc509d853c1b955
https://pubmed.ncbi.nlm.nih.gov/9918220
https://pubmed.ncbi.nlm.nih.gov/9918220
Autor:
J L, Rutter, T I, Mitchell, G, Butticè, J, Meyers, J F, Gusella, L J, Ozelius, C E, Brinckerhoff
Publikováno v:
Cancer research. 58(23)
Matrix metalloproteinases (MMPs) facilitate cellular invasion by degrading the extracellular matrix, and their regulation is partially dependent on transcription. Binding sites for members of the Ets family of transcription factors are present within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35f5f22591c4c9d6ce618c3d6376cc07
https://pubmed.ncbi.nlm.nih.gov/9850057
https://pubmed.ncbi.nlm.nih.gov/9850057