Zobrazeno 1 - 10
of 54
pro vyhledávání: '"C. Dominique Toran-Allerand"'
Autor:
C. Dominique Toran-Allerand
Publikováno v:
Annals of the New York Academy of Sciences. 1052:136-144
The brain of both sexes is a major target of estradiol and a site of estrogen synthesis during development and in the adult. In addition to the classical intranuclear estrogen receptors (ERs) ER-alpha and ER-beta, we have recently identified a novel,
Publikováno v:
Neurochemical Research. 30:779-790
Our laboratory showed previously that estrogen activates ERK in neocortical cultures. To further elucidate the precise signaling sequelae that lead to estrogen-induced ERK activity, we evaluated the involvement of protein kinase C (PKC). We found tha
Autor:
Tamas L. Horvath, C. Dominique Toran-Allerand, Xiaoping Guan, Sabrina Diano, E. Sander Connolly, Imam S. Nethrapalli, Neil J. MacLusky, Alexander A. Tinnikov, Meharvan Singh
Publikováno v:
The Journal of Neuroscience. 22:8391-8401
We showed previously in neocortical explants, derived from developing wild-type and estrogen receptor (ER)-alpha gene-disrupted (ERKO) mice, that both 17alpha- and 17beta-estradiol elicit the rapid and sustained phosphorylation and activation of the
Publikováno v:
Journal of Neurobiology. 50:1-12
Confocal laser scanning microscopy was used to identify the cells within organotypic slice cultures of the developing mouse cerebral cortex that respond to estradiol treatment by phosphorylation of ERK1 and ERK2. Estrogen-responsive cells resembled n
Autor:
Kenneth S. Korach, Xiaoping Guan, Imam S. Nethrapalli, C. Dominique Toran-Allerand, QiongFen Guo, Dennis B. Lubahn, Meharvan Singh
Publikováno v:
Endocrinology. 142:5145-5148
In neocortical explants, E2 activates various signaling components of the MAPK cascade, including B-Raf and MAPK kinase-dependent ERK, suggesting a possible role in the differentiative actions of E2 in the brain. To further characterize the signaling
Autor:
Ningning Guo, Imam S. Nethrapalli, C. Michael Astle, Kevin A. Schug, Li Li, David E. Harrison, Hien P. Nguyen, C. Dominique Toran-Allerand
Publikováno v:
Journal of separation science. 34(15)
Matrix effects of different biological samples, including phosphate-buffered saline-bovine serum albumin (PBS-BSA), gelded horse serum, mouse serum, and mouse brain, were investigated for the determination of 17α- and β-estradiol using derivatizati
Publikováno v:
Cerebral Cortex. 2:1-15
The distribution of estrogen receptor mRNA expression was studied in the developing rat cerebral cortex by in situ hybridization histochemistry. We used a specific, nonisotopically (digoxigenin) labeled, synthetic oligodeoxyribonucleotide complementa
Autor:
Silke A. von Esenwein, Sergei Musatov, Larry J. Young, Jill B. Becker, Kristin N. Schultz, Robert T. Kennedy, Michael G. Kaplitt, Amy L. Bennett, C. Dominique Toran-Allerand, Ming Hu
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(6)
Classical estrogen receptor-signaling mechanisms involve estradiol binding to intracellular nuclear receptors [estrogen receptor-α (ERα) and estrogen receptor-β (ERβ)] to promote changes in protein expression. Estradiol can also exert effects wit
Autor:
C. Dominique Toran-Allerand
Publikováno v:
Brain Research. 513:353-357
In living explants of the developing CNS ‘true’ neurites (neuronal processes) may appear virtually indistinguishable from the processes of radial and Bergmann glia. This inability to clearly distinguish the phenotype of responsive ‘neurites’
Autor:
C Dominique, Toran-Allerand
Publikováno v:
Annals of the New York Academy of Sciences. 1052
The brain of both sexes is a major target of estradiol and a site of estrogen synthesis during development and in the adult. In addition to the classical intranuclear estrogen receptors (ERs) ER-alpha and ER-beta, we have recently identified a novel,