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Down‐regulation of cyclooxygenase‐2 (COX‐2) by interleukin‐1 receptor antagonist in human monocytes

Autor: Marcella Reale, Pio Conti, Giovanna Baccante, M. Di Gioacchino, Franco Cuccurullo, Renato C. Barbacane, Ettore Porreca, M.L. Castellani, C. Di Febbo

Publikováno v: Immunology. 89:424-429

Cyclooxygenase (COX) is the key rate-limiting enzyme in the synthesis of prostanoids from arachidonic acid. Two isoforms of COX have been described in mammalian cells, referred to as cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cebadf83a672bb0f0fef50c435a5dcb
https://doi.org/10.1046/j.1365-2567.1996.d01-753.x

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Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo

Autor: Napolitano Am, Franco Cuccurullo, Domenico Angelucci, Andrea Mezzetti, Sante Ucchino, Ettore Porreca, C. Di Febbo, N Di Bartolomeo

Publikováno v: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 14:299-304

Vascular smooth muscle cell (VSMC) growth is a primary component of accelerated and spontaneous atherosclerosis. Previous studies have shown that iron may be involved in the control of enzymatic activities that modulate DNA synthesis in human cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53520b477ea2dae389017b4597c8492d
https://doi.org/10.1161/01.atv.14.2.299

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Microsatellite polymorphism of the human leptin gene (LEP) and risk of cardiovascular disease

Autor: M Di Nisio, Valentina Gatta, S Pintor, Franco Cuccurullo, C. Di Febbo, Valeria Moretta, Ettore Porreca, Giovanna Baccante, Chiara Palka, Liborio Stuppia

Publikováno v: International journal of obesity 30.2 (2006): 209–213.
info:cnr-pdr/source/autori:E. PORRECA, C. DI FEBBO, S. PINTOR, G. BACCANTE, V. GATTA, V. MORETTA, M.D. NISIO, C. PALKA, F. CUCCURULLO, L. STUPPIA,/titolo:Microsatellite polymorphism of the human leptin gene (LEP) and risk of cardiovascular disease,/doi:/rivista:International journal of obesity/anno:2006/pagina_da:209/pagina_a:213/intervallo_pagine:209–213/volume:30.2

No data have been so far reported on the relationship between polymorphisms of LEP gene and cardiovascular disease.We genotyped a tetranucleotide repeat mapped in the 3'UTR of the LEP gene (LEP-tet) in 109 subjects with cardiovascular events and in 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42c4d82a03deb38d2f74da169776ae4
https://pubmed.ncbi.nlm.nih.gov/16261186

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Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus

Autor: Giovanni Davì, M. Di Nicola, Angela Falco, Gino Avellone, C. Di Febbo, Ester Vitacolonna, Giovanni Ciabattoni, Antonio Pinto, F. Salvati, Enzo Ballone

Triflusal is an antiplatelet drug related to aspirin, with different pharmacological properties and a lower haemorrhagic risk. We aimed at comparing their effects on platelet and endothelial activation in type 2 diabetes mellitus (T2DM). In a randomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3b0239da26b1fc31eacdc72ad2820
http://hdl.handle.net/10447/2036

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Expression of interleukin 8 (IL-8) and substance P in human chronic pancreatitis

Autor: Markus W. Büchler, Ettore Porreca, Giovanna Baccante, C. Di Febbo, F.F. di Mola, Helmut Friess, Paolo Innocenti, P. Di Sebastiano

Publikováno v: Gut. 47(3)

BACKGROUND—Changes in substance P content and a relationship between the degree of perineural inflammation and pain has been demonstrated in chronic pancreatitis. Whether a relationship exists between neural alteration and pancreatic inflammation (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4b01b87bfd75628e5cc35b50e42de5
https://pubmed.ncbi.nlm.nih.gov/10940282

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Infra-red laser irradiation enhances interleukin-1 receptor antagonist, increases 3H-thymidine incorporation and the release of [3H]arachidonic acid in human monocytes

Autor: M, Reale, C, Orso, M L, Castellani, R C, Barbacane, F C, Placido, E, Porreca, C, Di Febbo, I, Cataldo, D, Vacalis, G, Anogianakis, A, Trakatellis, P, Conti

Publikováno v: Molecular and cellular biochemistry. 169(1-2)

The effect of infra-red laser irradiation has been experimented on various biological systems and particularly in human tissues, in vitro as well as in vivo. In order to examine the influence of laser irradiation on cells of the monocytic lineage we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a236b2a2dc6c2ee9dd1b72250ea92d2
https://pubmed.ncbi.nlm.nih.gov/9089631

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Cysteinyl leukotriene D4 induced vascular smooth muscle cell proliferation: a possible role in myointimal hyperplasia

Autor: Franco Cuccurullo, Ettore Porreca, Domenico Angelucci, Andreina Poggi, Mimmo Nasuti, P Vitullo, A Di Sciullo, Pio Conti, C. Di Febbo, Marcella Reale

Publikováno v: Thrombosis and haemostasis. 76(1)

SummaryCysteinyl leukotrienes (i.e. LTC4, LTD4), produced by activated leukocytes or by transcellular metabolism may act at different levels on vascular smooth muscle cells (VSMC) during inflammatory processes or atherosclerosis. We studied the effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691ac6fc0c6d16722cd291b822b513a4
https://pubmed.ncbi.nlm.nih.gov/8819260

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