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of 272
pro vyhledávání: '"C. Demougeot"'
Autor:
C. Peyronnel, P. Totoson, V. Petitcolin, F. Bonnefoy, X. Guillot, P. Saas, F. Verhoeven, H. Martin, C. Demougeot
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Aim This study explored the systemic vascular effects of local cryotherapy with a focus on endothelial changes and arterial inflammation in the model of rat adjuvant-induced arthritis (AIA). Methods Cryotherapy was applied twice a day on hin
Externí odkaz:
https://doaj.org/article/b49d30876c244456beb30edafdec1b48
Akademický článek
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Human-based evidence for the therapeutic potential of arginase inhibitors in cardiovascular diseases
Publikováno v:
Drug Discovery Today
Drug Discovery Today, Elsevier, 2021, 26 (1), pp.138-147. ⟨10.1016/j.drudis.2020.11.005⟩
Drug Discovery Today, Elsevier, 2021, 26 (1), pp.138-147. ⟨10.1016/j.drudis.2020.11.005⟩
Arginase is a ubiquitous enzyme that regulates polyamine- and nitric-oxide-requiring vascular functions. It is well-established that, in mammals, arginase overactivation contributes to endothelial dysfunction, a hallmark of cardiovascular diseases. T
Publikováno v:
Revue du Rhumatisme. 89:A263-A264
Publikováno v:
Joint Bone Spine. 87:413-418
Introduction Psoriatic arthritis (PsA) is a chronic inflammatory rheumatism characterized for a long time by a high degree of cardiovascular risk. Chronic inflammation is one of the mechanisms that explain this cardiovascular excess of risk through d
Publikováno v:
South African Journal of Botany
South African Journal of Botany, Elsevier, 2019, 120, pp.313-318. ⟨10.1016/j.sajb.2018.09.022⟩
South African Journal of Botany, Elsevier, 2019, 120, pp.313-318. ⟨10.1016/j.sajb.2018.09.022⟩
Arginase has been the focus of a particular interest since it has been shown that the increase of its activity is involved in various pathologies for which the inhibition of this enzyme could be a promising treatment. The several existing synthetic i
Autor:
H. Martin, V. Petitcolin, Philippe Saas, Xavier Guillot, Perle Totoson, C. Peyronnel, C. Demougeot, F. Bonnefoy
Publikováno v:
Revue du Rhumatisme. 88:A124-A125
Publikováno v:
Annals of the Rheumatic Diseases. 81:1186.1-1186
BackgroundGrowing evidence indicated that the intestine is not only a target but also an actor of the pathogenesis in chronic inflammatory rheumatic diseases (CIRD). Consistently, increased intestinal permeability (IP) and damage (ID) as well as bact
Autor:
C. Peyronnel, P. Totoson, V. Petitcolin, F. Bonnefoy, F. Verhoeven, X. Guillot, P. Saas, H. Martin, C. Demougeot
Publikováno v:
Annals of the Rheumatic Diseases. 81:464.1-464
BackgroundRheumatoid arthritis (RA) is characterized by endothelial activation (EA), endothelial dysfunction and vascular inflammation, leading to accelerated atherosclerosis. In the last decade, a renewed interest in cryotherapy - local or whole bod
Autor:
Clément Prati, Amit Kumar, Daniel Wendling, Perle Totoson, Sébastien Pasquereau, Frank Verhoeven, Zeina Nehme, C. Demougeot, Georges Herbein, Wasim Abbas
Publikováno v:
Epigenetics
The class III histone deacetylase sirtuin 1 (SIRT1) plays a pivotal role in numerous biological and physiological functions, including inflammation. An association between SIRT1 and proinflammatory cytokines might exist. In addition to their importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c188a65d6ae959357b82854f8a47f7