Zobrazeno 1 - 10
of 91
pro vyhledávání: '"C. DeFelice"'
Autor:
Takeshi Tsusaka, Juan A. Oses-Prieto, Christina Lee, Brian C. DeFelice, Alma L. Burlingame, Emily L. Goldberg
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107235- (2023)
Summary: Ketone bodies are short-chain fatty acids produced in the liver during periods of limited glucose availability that provide an alternative energy source for the brain, heart, and skeletal muscle. Beyond this metabolic role, β-hydroxybutyrat
Externí odkaz:
https://doaj.org/article/2f93bf1dffc04c3f838dc092a45f7ba9
Autor:
Cecilia Noecker, Juan Sanchez, Jordan E Bisanz, Veronica Escalante, Margaret Alexander, Kai Trepka, Almut Heinken, Yuanyuan Liu, Dylan Dodd, Ines Thiele, Brian C DeFelice, Peter J Turnbaugh
Publikováno v:
PLoS Biology, Vol 21, Iss 5, p e3002125 (2023)
Human gut bacteria perform diverse metabolic functions with consequences for host health. The prevalent and disease-linked Actinobacterium Eggerthella lenta performs several unusual chemical transformations, but it does not metabolize sugars and its
Externí odkaz:
https://doaj.org/article/4aca52c64575452cb35fdf8e9432cf85
Autor:
Abby Sarkar, Yinhua Jin, Brian C DeFelice, Catriona Y Logan, Yan Yang, Teni Anbarchian, Peng Wu, Maurizio Morri, Norma F Neff, Huy Nguyen, Eric Rulifson, Matthew Fish, Avi Gurion Kaye, Azalia M Martínez Jaimes, Roel Nusse
Publikováno v:
eLife, Vol 12 (2023)
Nutrient availability fluctuates in most natural populations, forcing organisms to undergo periods of fasting and re-feeding. It is unknown how dietary changes influence liver homeostasis. Here, we show that a switch from ad libitum feeding to interm
Externí odkaz:
https://doaj.org/article/fe8e1759692e4b93a965fbb77529eaf8
Autor:
Jessica Spring, Vera Beilinson, Brian C. DeFelice, Juan M. Sanchez, Michael Fischbach, Alexander Chervonsky, Tatyana Golovkina
Publikováno v:
Viruses, Vol 15, Iss 2, p 386 (2023)
Both viruses and bacteria produce “pathogen associated molecular patterns” that may affect microbial pathogenesis and anti-microbial responses. Additionally, bacteria produce metabolites, while viruses could change the metabolic profiles of the i
Externí odkaz:
https://doaj.org/article/de175d4fd6454ba1aa7d7dbbf05ea48d
Autor:
Brian C. DeFelice, Oliver Fiehn, Peter Belafsky, Constanze Ditterich, Michael Moore, Marianne Abouyared, Angela M. Beliveau, D. Gregory Farwell, Arnaud F. Bewley, Shannon M. Clayton, Joehleen A. Archard, Jordan Pavlic, Shyam Rao, Maggie Kuhn, Peter Deng, Julian Halmai, Kyle D. Fink, Andrew C. Birkeland, Johnathon D. Anderson
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 797 (2022)
Background: Novel, non-invasive diagnostic biomarkers that facilitate early intervention in head and neck cancer are urgently needed. Polyamine metabolites have been observed to be elevated in numerous cancer types and correlated with poor prognosis.
Externí odkaz:
https://doaj.org/article/bfcb0005f6684b4da7b98da07248dadf
Autor:
Tim Vigers, Lauren A. Vanderlinden, Randi K. Johnson, Patrick M. Carry, Ivana Yang, Brian C. DeFelice, Alexander M. Kaizer, Laura Pyle, Marian Rewers, Oliver Fiehn, Jill M. Norris, Katerina Kechris
Publikováno v:
Metabolites, Vol 11, Iss 8, p 542 (2021)
Environmental factors including viruses, diet, and the metabolome have been linked with the appearance of islet autoimmunity (IA) that precedes development of type 1 diabetes (T1D). We measured global DNA methylation (DNAm) and untargeted metabolomic
Externí odkaz:
https://doaj.org/article/714dbdf695d241429a1a4ba14acd0040
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Akademický článek
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Akademický článek
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Autor:
Suzanne Miyamoto, Karen Kelly, Oliver Fiehn, David T. Cooke, Ken Y. Yoneda, David R. Gandara, Sandra L. Taylor, Brian C. DeFelice, Kyoungmi Kim, Johannes F. Fahrmann
Word - 708 KB, Supplementary Materials and Methods. Supplemental Table S1. All detected serum metabolites in ADC1 Training and ADC2 Test set. Supplemental Table S2. All detected plasma metabolites in ADC1 Training and ADC2 Test set. Supplemental Tabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d654d13882968d7aafec989491210a17
https://doi.org/10.1158/1055-9965.22436937
https://doi.org/10.1158/1055-9965.22436937
