Zobrazeno 1 - 10
of 54
pro vyhledávání: '"C. De Saeger"'
Autor:
Isabelle Leclercq, Peter Stärkel, Ivan Borbath, Jorge Abarca, C. De Saeger, Yves Horsmans, N. Charette, T. Schneider-Merck
Publikováno v:
European Journal of Cancer. 45:2050-2060
BACKGROUND: Aberrant activation of oncogenes, such as Ras, likely contributes to the development of hepatocarcinoma (HCC). AIMS/METHODS: We evaluated in vivo the effect of intraperitoneal injections of the Ras inhibitor S-trans, trans-farnesylthiosal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5bd3f7a254fc70f35f6621cb560525
https://doi.org/10.1016/j.ejca.2009.04.014
https://doi.org/10.1016/j.ejca.2009.04.014
Publikováno v:
European Journal of Clinical Investigation. 38:397-403
Background Conflicting data concerning the involvement of ghrelin in the pathophysiology of alcohol dependence have been reported. The aim of this study is to investigate how chronic alcohol ingestion influences plasma ghrelin levels and whether pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0dae745054eb2833715377558b257ab
https://doi.org/10.1111/j.1365-2362.2008.01947.x
https://doi.org/10.1111/j.1365-2362.2008.01947.x
Autor:
Christine Sempoux, Luc Lambotte, C. De Saeger, Dominique Maiter, Peter Stärkel, Y. Horsmans, Alain Saliez
Publikováno v:
Gut, Vol. 49, no. 1, p. 119-130 (2001)
BACKGROUND—In liver regeneration after portal branch ligation we previously showed that early cellular changes are observed in both the proliferating and atrophying liver lobes. They are therefore not indicative of future proliferative response. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768e47e8689770eff6a3968597537cf7
https://doi.org/10.1136/gut.49.1.119
https://doi.org/10.1136/gut.49.1.119
Publikováno v:
Cell Death & Disease, Vol. 4, no.epub, p. e471 (2013)
Cell Death & Disease
Cell Death & Disease
Ras activation is a frequent event in human hepatocarcinoma that may contribute to resistance towards apoptosis. Salirasib is a ras and mTOR inhibitor that induces a pro-apoptotic phenotype in human hepatocarcinoma cell lines. In this work, we evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da0eb629240f8bde217c1d957906a8a
https://hdl.handle.net/2078.1/136289
https://hdl.handle.net/2078.1/136289
Publikováno v:
European journal of clinical investigation. 38(6)
Conflicting data concerning the involvement of ghrelin in the pathophysiology of alcohol dependence have been reported. The aim of this study is to investigate how chronic alcohol ingestion influences plasma ghrelin levels and whether potential chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b91846f3df62b453b5055fa9cc102a5
https://pubmed.ncbi.nlm.nih.gov/18422979
https://pubmed.ncbi.nlm.nih.gov/18422979
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:819-822
We report a three-step synthesis of thymidine, starting from trace amounts of urea, that allows rapid introduction of radioactivity in C2-position of the pyrimidine ring. Thymine was produced within 5 min with a 60% yield by cyclocondensation of urea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a78a81a2bd678486c7fb9f1b645646c
https://doi.org/10.1002/jlcr.2580280711
https://doi.org/10.1002/jlcr.2580280711
Publikováno v:
Alcohol and Alcoholism. 50:i12.2-i12
Background. Alcohol-dependent (AD) subjects are characterized by increased intestinal permeability, elevated blood lipopolysaccharides (LPS) levels and low-grade inflammation that was shown to be associated with psychological symptoms of alcohol-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fa56aba4deba6bdfafff9a27cffd99f
https://doi.org/10.1093/alcalc/agv076.41
https://doi.org/10.1093/alcalc/agv076.41
Autor:
Isabelle Leclercq, Peter Stärkel, C. De Saeger, Christine Sempoux, Nicolas Lanthier, Y. Horsmans
Publikováno v:
Journal of Hepatology. 60:S176
Background and aims : Animal data suggest a pathogenic role for TLR4 with subsequent activation of NFkB in alcohol liver injury. Here, we assessed cytokines, TLR and TLR-dependent pathways expressions in human ALD. Methods : Liver biopsies from 41 ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ccf60b0e7d9eddf29c5dd9e9b05edff
https://doi.org/10.1016/s0168-8278(14)60492-x
https://doi.org/10.1016/s0168-8278(14)60492-x
Publikováno v:
Hepatology (Baltimore, Md.). 29(5)
Several studies have emphasized the involvement of transcription factors, cytokines, and proto-oncogenes in initiating the regenerative process after partial hepatectomy. To assess whether these events do specifically occur in a cellular system under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b2e32def9d1044996736ddb5579cef6
https://pubmed.ncbi.nlm.nih.gov/10216130
https://pubmed.ncbi.nlm.nih.gov/10216130
Autor:
C. De Saeger, Y. Horsmans, N. Charette, Isabelle Leclercq, Ivan Borbath, Jorge Abarca, Peter Stärkel, T. Schneider-Merck
Publikováno v:
International Journal of Infectious Diseases. 12:S1-S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fc26ee8984820619d37be81c3bc184
https://doi.org/10.1016/s1201-9712(09)60006-0
https://doi.org/10.1016/s1201-9712(09)60006-0