Zobrazeno 1 - 10
of 26
pro vyhledávání: '"C. David Wood"'
Publikováno v:
International Journal of Biological Sciences, Vol 5, Iss 5, Pp 428-437 (2009)
p38 MAP kinase (MAPK) is activated in response to environmental stress, cytokines and DNA damage, and mediates death, cell differentiation and cell cycle checkpoints. The intracellular localization of p38 MAPK upon activation remains unclear, and may
Externí odkaz:
https://doaj.org/article/547a81a4416045e4a218f05223a7af37
Autor:
Sarika Khasnis, Hildegonda Veenstra, Michael J. McClellan, Opeoluwa Ojeniyi, C. David Wood, Michelle J. West
Publikováno v:
Biochemical Journal. 479:2395-2417
The cancer-associated Epstein–Barr virus (EBV) latently infects and immortalises B lymphocytes. EBV latent membrane protein 2A and EBV-encoded microRNAs are known to manipulate B cell receptor signalling to control cell growth and survival and supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bbb329c2166e8476eaa873a67b1ace
https://doi.org/10.1042/bcj20220417
https://doi.org/10.1042/bcj20220417
Autor:
Rajesh Ponnusamy, Ritika Khatri, Paulo B Correia, C David Wood, Erika J Mancini, Paul J Farrell, Michelle J West
Publikováno v:
PLoS Pathogens, Vol 15, Iss 7, p e1007458 (2019)
Natural variation separates Epstein-Barr virus (EBV) into type 1 and type 2 strains. Type 2 EBV is less transforming in vitro due to sequence differences in the EBV transcription factor EBNA2. This correlates with reduced activation of the EBV oncoge
Externí odkaz:
https://doaj.org/article/d632892b25734a9aacfd5e80f581287a
Autor:
Ieisha Pentland, Karen Campos-León, Marius Cotic, Kelli-Jo Davies, C David Wood, Ian J Groves, Megan Burley, Nicholas Coleman, Joanne D Stockton, Boris Noyvert, Andrew D Beggs, Michelle J West, Sally Roberts, Joanna L Parish
Publikováno v:
PLoS Biology, Vol 16, Iss 10, p e2005752 (2018)
The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted. Upon epithelial differentiation, E6/E7 transcription is increased t
Externí odkaz:
https://doaj.org/article/2b634e44faf441ed83f18dab7b93bedd
Autor:
Alessandro Agnarelli, Simon Mitchell, Gillian Caalim, C. David Wood, Leanne Milton‐Harris, Timothy Chevassut, Michelle J. West, Erika J. Mancini
Publikováno v:
Hematological oncology. 40(3)
B-cell progenitor fate determinant interferon regulatory factor 4 (IRF4) exerts key roles in the pathogenesis and progression of multiple myeloma (MM), a currently incurable plasma cell malignancy. Aberrant expression of IRF4 and the establishment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36915699f99ef90732d7e2841e56318
https://pubmed.ncbi.nlm.nih.gov/35544413
https://pubmed.ncbi.nlm.nih.gov/35544413
Autor:
C David Wood, Hildegonda Veenstra, Sarika Khasnis, Andrea Gunnell, Helen M Webb, Claire Shannon-Lowe, Simon Andrews, Cameron S Osborne, Michelle J West
Publikováno v:
eLife, Vol 5 (2016)
Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apoptosis, often through downregulation of the pro-apoptotic BCL2L11 gene (Bim). Transcription factors (EBNAs) encoded by the lymphoma-associated Epstein-Barr virus
Externí odkaz:
https://doaj.org/article/d0168bf945bb4d54b7a76064f2dbc58e
Autor:
Rajesh, Ponnusamy, Ritika, Khatri, Paulo B, Correia, C David, Wood, Erika J, Mancini, Paul J, Farrell, Michelle J, West
Publikováno v:
PLoS Pathogens
Natural variation separates Epstein-Barr virus (EBV) into type 1 and type 2 strains. Type 2 EBV is less transforming in vitro due to sequence differences in the EBV transcription factor EBNA2. This correlates with reduced activation of the EBV oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8af0b9b64b54fba263c053d760fc0e70
https://pubmed.ncbi.nlm.nih.gov/31283782
https://pubmed.ncbi.nlm.nih.gov/31283782
Autor:
Michelle J. West, Andrea Gunnell, C. David Wood, Thomas Carvell, Cameron S. Osborne, Opeoluwa O. Ojeniyi
The oncogenic microRNA-155 (miR-155) is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in other non-viral lymphomas. Both the EBV nuclear antigen 2 (EBNA2), and B cell transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdde14df0e6bd768538c8c7b4b3e69e4
https://doi.org/10.1101/311886
https://doi.org/10.1101/311886
Autor:
C David, Wood, Thomas, Carvell, Andrea, Gunnell, Opeoluwa O, Ojeniyi, Cameron, Osborne, Michelle J, West
Publikováno v:
Journal of Virology
The oncogenic microRNA (miRNA) miR-155 is the most frequently upregulated miRNA in Epstein-Barr virus (EBV)-positive B cell malignancies and is upregulated in other nonviral lymphomas. Both EBV nuclear antigen 2 (EBNA2) and the B cell transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd3e7b456d5d32597d6893dedf2247e0
https://pubmed.ncbi.nlm.nih.gov/30655383
https://pubmed.ncbi.nlm.nih.gov/30655383
Publikováno v:
Nucleic Acids Research
Response gene to complement-32 (RGC-32) activates cyclin-dependent kinase 1, regulates the cell cycle and is deregulated in many human tumours. We previously showed that RGC-32 expression is upregulated by the cancer-associated Epstein-Barr virus (EB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c446c774507318f0e0d2ffb61125b362
https://pubmed.ncbi.nlm.nih.gov/29385536
https://pubmed.ncbi.nlm.nih.gov/29385536