Zobrazeno 1 - 10
of 38
pro vyhledávání: '"C. David L. Thomas"'
Autor:
Isabel S. Maggiano, Corey M. Maggiano, Yasmin Carter, C. David L. Thomas, David M. L. Cooper, John G. Clement
Publikováno v:
Journal of Anatomy. 228:719-732
This study uses synchrotron radiation‐based micro‐computed tomography (CT) scans to reconstruct three‐dimensional networks of Haversian systems in human cortical bone in order to observe and analyse interconnectivity of Haversian systems and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::109b65870c62fc2d773512892eff160f
https://doi.org/10.1111/joa.12430
https://doi.org/10.1111/joa.12430
Publikováno v:
Journal of Anatomy. 225:328-336
The most abundant cell in bone, osteocytes form an interconnected system upon which the regulation of healthy bone relies. Although the complete nature of the role of osteocytes has yet to be defined, they are generally accepted to play a part in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068696bf6ac3439b39ceec68c7ff420f
https://doi.org/10.1111/joa.12213
https://doi.org/10.1111/joa.12213
Publikováno v:
International Journal for Numerical Methods in Biomedical Engineering. 29:1307-1322
Age-related bone loss and postmenopausal osteoporosis are disorders of bone remodelling, in which less bone is reformed than resorbed. Yet, this dysregulation of bone remodelling does not occur equally in all bone regions. Loss of bone is more pronou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093f63894275a47ef9699dc1d45575de
https://doi.org/10.1002/cnm.2567
https://doi.org/10.1002/cnm.2567
Autor:
David M.L. Cooper, Kevin. Hannah, Andrew G. Peele, Yasmin Carter, John G. Clement, C. David L. Thomas
Publikováno v:
Bone. 52:126-132
In recent years there has been growing interest in the spatial properties of osteocytes (including density and morphology) and how these potentially relate to adaptation, disease and aging. This interest has, in part, arisen from the availability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e98a14073ea60c79353ef341dba1b25
https://doi.org/10.1016/j.bone.2012.09.010
https://doi.org/10.1016/j.bone.2012.09.010
Autor:
J. Power, Nigel Loveridge, John G. Clement, PM Mayhew, Kenneth E. S. Poole, C. David L. Thomas, Jonathan Reeve, CJ Burgoyne
Publikováno v:
Journal of Bone and Mineral Research. 24:1808-1818
Hip fracture risk rises 100- to 1000-fold over six decades of age, but only a minor part of this increase is explained by declining BMD. A potentially independent cause of fragility is cortical thinning predisposing to local crushing, in which bone t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea32c1f8440000b89c963bf0c0576d2
https://doi.org/10.1359/jbmr.090504
https://doi.org/10.1359/jbmr.090504
Publikováno v:
American Journal of Physical Anthropology. 133:808-816
We have measured the (14)C content of human femoral mid-shaft collagen to determine the dynamics of adult collagen turnover, using the sudden doubling and subsequent slow relaxation of global atmospheric (14)C content due to nuclear bomb testing in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024386a043434201e06e62120ee9dd96
https://doi.org/10.1002/ajpa.20598
https://doi.org/10.1002/ajpa.20598
The primary microstructural unit of cortical bone, the secondary osteon or Haversian system, is widely assumed to have a cylindrical shape. It is generally accepted that osteons are roughly circular in cross-section and deviations from circularity ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9a5c6f6700788d90638c761fc0d778
https://europepmc.org/articles/PMC4580107/
https://europepmc.org/articles/PMC4580107/
Publikováno v:
Journal of Anatomy. 209:219-230
This study investigated the relative contributions of pore size and pore density (number of pores per mm2) to porosity in the midshaft of the human femur. Cross-sections were obtained from 168 individuals from a modern Australian population (mostly A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec249e3a765d237af90ae7fae9b9972
https://doi.org/10.1111/j.1469-7580.2006.00589.x
https://doi.org/10.1111/j.1469-7580.2006.00589.x
Autor:
Jonathan Reeve, John G. Clement, William Bonfield, C. David L. Thomas, PM Mayhew, Nigel Loveridge, CJ Burgoyne, Thomas J. Beck
Publikováno v:
The Lancet. 366:129-135
BACKGROUND: Hip fracture risk rises 100 to 1000-fold over 60 years of ageing. Loss of resistance to bending is not a major feature of normal ageing of the femoral neck. Another cause of fragility is local buckling or elastic instability. Bones adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0400a8c3512718d4b9221a9ecd7ee2b
https://doi.org/10.1016/s0140-6736(05)66870-5
https://doi.org/10.1016/s0140-6736(05)66870-5