Abstracts

Autor: S. Rosemberg, M. J. Telxelra, V. A. F. Alves, J. R. Perry, L. C. Ang, J. M. Bilbao, P. J. Muller, Kyung -Whan Min, Robert Cashman, Roger A. Brumback, C. Rao, D. Deloso, V. Anderson, A. Seymour, M. Wrzolek, A. Abdu, R. Swanson, M. Honavar, K. B. Waters, S. M. Wise, T. Kubota, K. Sato, M. Kabuto, T. Nakagawa, R. Kitai, H. Nitta, J. Yamashita, C. Vital, J. Rivel, F. Sangalli, B. Benjelloun, A. Vital, F. Leger, V. Riemens, B. Epardeau, J. Guerin, J. M. Coindre, M. M. Ruchoux, P. Dhellemmes, M. Hamon, M. Lecomte, J. Hassoun, Saburo Yagishita, Nobuyuki Kawano, Toru Kameya, R. Bowman, B. H. Liwnicz, N. Peckham, L. M. Barbosa-Coutinho, L. M. Hilbig, A. Hilbig, H. Loiseau, L. Mouton, H. B. Delisle, C. Rummens, F. Akai, M. Taneda, H. Iwasaki, Y. Suzuki, A. M. C. Tsanaclis, P. H. P. Aguiar, A. F. Logullo, M. R. Matamores, A. Yacubian, H. Komatsu, H. Oka, T. Suwa, G. Stoltenburg-Didinger, C. Gotzia, G. Benndorf, J. J. Kepes, R. Baba-Ahmed, K. Wong, J. Raisanen, S. L. Taylor, M. W. McDermott, P. Gutin, Necat Havlioglu, Anantha Manepalli, Lorenzo Galindo, Cirilo Sotelo-Avila, Leonard Grosso, S. Kavavattathayyil, P. Chen, M. A. Wrzolek, J. Cook, D. E. Woodward, P. Tracqui, G. C. Cruywagen, J. D. Murray, G. T. Bartoo, E. C. Alvord, Janusz Szymas, Jacek Jelonek, Krzysztof Krawiec, Roman Slowinski, S. W. Coons, P. C. Johnson, E. Uro, P. H. Bousquet, M. B. Delisle, C. H. U. Rangueil, S. H. Torp, E. Johannesen, C. F. Lindboe, Michael Beil, S. Kato, T. Morita, M. Kato, F. Herz, A. Hirano, E. Ohama, L. Albuquerque, J. Pimentel, L. Távora, N. L. Antunes, S. Weis, D. Protopapa, U. Mäerz, P. A. Winkler, H. J. Reulen, P. Mehraein, Xiao Di, Julia Reifenberger, Guido Reifenberger, Lu Liu, C. David James, Wolfgang Wechsler, V. Peter Collins, R. E. McLendon, S. K. Batra, H. S. Friedman, B. K. A. Rasheed, D. D. Bigner, S. K. Bigner, S. Patt, G. Thiel, F. Labrousse, B. de Néchaud, D. Gomès, C. Daumas-Duport, C. Allarmargot, P. Dupouey, F. Vrionis, P. Qi, V. Cherington, G. Cano, J. Wu, L. A. Lampson, A. Chen, A. O. Vortmeyer, R. S. Slack, I. S. Skerjanc, B. Lach, J. Craig, K. Jardine, M. W. McBurney, R. J. B. Macaulay, J. Dimitroulakos, L. E. Becker, H. Yeger, C. Harker Rhodes, Charles Honsinger, George D. Sorenson, L. C. Goumnerova, R. A. Segal, Y. K. Kwon, C. D. Stiles, S. L. Pomeroy, A. Guha, N. Lau, A. Pawson, Ute Engel, Nick J. Gutowski, Karen Bevan, Mark Noble, C. L. Gladson, V. Pijuan, M. A. Olman, G. Y. Gillespie, I. Yacoub, T. Yamasaki, K. Enomoto, K. Moritake, Y. Akiyama, M. Kawahara, T. Maeno, A. Merzak, C. Parker, S. Koocheckpour, G. V. Sherbet, G. J. Pilkington, K. Martin, J. Akinwunmi, H. K. Rooprai, A. Kennedy, A. Linke, N. Ognjenovic, T. Fujiwara, Y. Matsumoto, K. Miyake, M. Shin, S. Nagao, G. Pulido-Cejudo, K. Jamison, H. Hugenholtz, J. Campione-Piccardo, S. L. Maidment, C. Lins, C. M. Takyia, J. Garcia-Abreu, F. F. Rodrigues, F. Duarte, C. Chagas, H. Chneiweiss, V. Moura Neto

Publikováno v: Journal of Neuro-Oncology. 24:125-139

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::970f25dca0c2f0718be88a6f2c7fa9e3
https://doi.org/10.1007/bf01052669

Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class

Autor: T, Kilic, J A, Alberta, P R, Zdunek, M, Acar, P, Iannarelli, T, O'Reilly, E, Buchdunger, P M, Black, C D, Stiles

Publikováno v: Cancer research. 60(18)

Glioblastoma multiforme is the most common primary human brain tumor, and it is, for all practical purposes, incurable in adult patients. The high mortality rates reflect the fact that glioblastomas are resistant to adjuvant therapies (radiation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bcec8ef45821a932227e9e463abdfad8
https://pubmed.ncbi.nlm.nih.gov/11016641

Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas

Autor: J Y, Kim, M E, Sutton, D J, Lu, T A, Cho, L C, Goumnerova, L, Goritchenko, J R, Kaufman, K K, Lam, A L, Billet, N J, Tarbell, J, Wu, J C, Allen, C D, Stiles, R A, Segal, S L, Pomeroy

Publikováno v: Cancer research. 59(3)

Elevated expression of the neurotrophin-3 (NT-3) receptor TrkC by childhood medulloblastomas is associated with favorable clinical outcome. Here, we provide evidence that TrkC is more than simply a passive marker of prognosis. We demonstrate that: (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a75d8d0e49e33d96a6afc2969e00cf5b
https://pubmed.ncbi.nlm.nih.gov/9973222

Phosphorylation-directed antibodies in high-flux screens for compounds that modulate signal transduction

Autor: J A, Alberta, C D, Stiles

Publikováno v: BioTechniques. 23(3)

Synthetic tyrosine phosphopeptides were used to generate antibodies that recognize phosphotyrosine in the context of a defined sequence of flanking amino acids. Using phosphopeptide immunogens derived from regulatory or signal-generating motifs, "pho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef4a794e32cdc6d41df351fad6c38f33
https://pubmed.ncbi.nlm.nih.gov/9298221

Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator

Autor: R R, Freter, J A, Alberta, G Y, Hwang, A L, Wrentmore, C D, Stiles

Publikováno v: The Journal of biological chemistry. 271(29)

A broad panel of agents including serum, interleukin-1, double-stranded RNA, and platelet-derived growth factor (PDGF) stimulate transcription of the "slow" immediate-early gene MCP-1. These disparate inducers act through a tight cluster of regulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6e2738ab45e59c218fc6436ee6385c9
https://pubmed.ncbi.nlm.nih.gov/8663287