Cannabinoids and psychotic symptoms: A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene

Autor: Tomáš Paus, Patricia J. Conrod, Christiaan H. Vinkers, Elly M. Hol, Marco P. Boks, Lot de Witte, René S. Kahn, Guillaume Huguet, Willemijn A. van Gastel, Yujie He, C. D. Schubart, Kristel R. van Eijk, Laurent Elkrief

Publikováno v: Brain, Behavior, and Immunity, 88, 573-581. Academic Press Inc.
Boks, M P, He, Y, Schubart, C D, Gastel, W V, Elkrief, L, Huguet, G, Eijk, K V, Vinkers, C H, Kahn, R S, Paus, T, Conrod, P, Hol, E M & de Witte, L D 2020, ' Cannabinoids and psychotic symptoms : A potential role for a genetic variant in the P2X purinoceptor 7 (P2RX7) gene ', Brain, Behavior, and Immunity, vol. 88, pp. 573-581 . https://doi.org/10.1016/j.bbi.2020.04.051
Brain, Behavior, and Immunity, 88, 573-581. Academic Press

To investigate the biological mechanisms underlying the higher risk for psychosis in those that use cannabis, we conducted a genome-wide environment-interaction study (GWEIS). In a sample of individuals without a psychiatric disorder (N = 1262), we a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac07c102520e2edc07d49866f3b6dbad
https://pubmed.ncbi.nlm.nih.gov/32629043

Change in cannabis use in the general population: A longitudinal study on the impact on psychotic experiences

Autor: James H. MacCabe, René S. Kahn, C. D. Schubart, W. A. van Gastel, Marco P. Boks, Annabel Vreeker

Publikováno v: Schizophrenia research, 157(1-3), 266-270. Elsevier

article i nfo Objective: To prospectively assess the relationship between cannabis use and psychotic experiences over time. Method: In a longitudinal design,young adults aged 18-27 years (N = 705) gave online information on cannabis use and completed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb3a9010b6f745b3eadcb9868499f06
https://doi.org/10.1016/j.schres.2014.04.023

Cannabidiol as a potential treatment for psychosis

Autor: Paolo Fusar-Poli, Iris E. C. Sommer, L D de Witte, C. D. Schubart, Marco P. Boks, R.S. Kahn

Publikováno v: European Neuropsychopharmacology. 24:51-64

Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the developmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98036032aa077587aa5bfc629e22d0e4
https://doi.org/10.1016/j.euroneuro.2013.11.002

Liprin alfa 2 gene expression is increased by cannabis use and associated with neuropsychological function

Autor: Simone de Jong, Lot de Witte, Willemijn A. van Gastel, Bobby P. C. Koeleman, Marco P. Boks, Elly M. Hol, Roel A. Ophoff, C. D. Schubart, Yujie He

Publikováno v: European Neuropsychopharmacology, 29(5), 643. Elsevier
European Neuropsychopharmacology, 29, 643-652. Elsevier B.V.

The relation of heavy cannabis use with decreased neuropsychological function has frequently been described but the underlying biological mechanisms are still largely unknown. This study investigates the relation of cannabis use with genome wide gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ad70b9b9d22a56fbc1d5dc5a5d8605
https://doi.org/10.1016/j.euroneuro.2019.03.004

Treatment of unipolar psychotic depression: The use of evidence in practice guidelines

Autor: Willem A. Nolen, C. D. Schubart, Jaap Wijkstra

Publikováno v: World journal of biological psychiatry, 10(4), 409-415. Taylor & Francis Ltd

Introduction. In a recent meta-analysis we found no evidence that an antidepressant plus an antipsychotic is more effective than an antidepressant alone in unipolar psychotic depression. However, most current guidelines recommend the combination over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce74fb03ea5022d8296e24977b28601
https://doi.org/10.1080/15622970701599052