Zobrazeno 1 - 10
of 44
pro vyhledávání: '"C. D. Platsoucas"'
Publikováno v:
The Journal of Immunology. 146:1700-1707
CTL clones were developed from tumor infiltrating lymphocytes (TIL) from the ascites of a patient with ovarian carcinoma by coculture of TIL with autologous tumor cells and subsequent cloning in the presence of autologous tumor cells. These CTL clone
Autor:
B, Xu, L I, Sakkas, C A, Slachta, B I, Goldman, V, Jeevanandam, E L, Oleszak, C D, Platsoucas
Publikováno v:
Transplantation. 71(8)
We investigated the role of apoptosis (programed cell death) in the pathogenesis of chronic rejection.Epicardial coronary arteries from cardiac allografts with chronic rejection were examined for apoptosis by the TUNEL assay. Double labeling was carr
Autor:
R S, Freedman, A P, Kudelka, J J, Kavanagh, C, Verschraegen, C L, Edwards, M, Nash, L, Levy, E N, Atkinson, H Z, Zhang, B, Melichar, R, Patenia, S, Templin, W, Scott, C D, Platsoucas
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
To identify strategies that enhance tumor-specific immunity in patients with ovarian carcinoma, 22 patients received four to six doses of i.p. recombinant IFN-gamma (rIFN-gamma), 200 microg/m2 on days 1, 3, 5, 8, 10, and 12, and i.p. recombinant inte
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(11)
A newly described subset of monocytes has been identified in peritoneal exudate cells (PEC) from the malignant ascites from patients with ovarian cancer. These cells were characterized by the production of IL-10 and TGF-beta2, but not IL-12, IL-1alph
Autor:
M E, Gordinier, H Z, Zhang, R, Patenia, L B, Levy, E N, Atkinson, M A, Nash, R L, Katz, C D, Platsoucas, R S, Freedman
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(9)
Transforming growth factor beta (TGF-beta) is an important family of cytokines that may promote tumor growth in vivo through several mechanisms including interference with antitumor T-cell immune responses, alteration of factors in the stroma and mat
Publikováno v:
Cytokines, cellularmolecular therapy. 4(2)
Carcinomas that originate in the ovary or from different sites in the gastrointestinal tract frequently develop metastases that involve the peritoneal and serosal surfaces. Carcinomatous involvement of the peritoneum is a significant cause of morbidi
Publikováno v:
Hematopathology and molecular hematology. 11(2)
We employed the nonpalindromic adaptor-PCR (NPA-PCR) method to amplify T-cell receptor (TCR) alpha- and beta-chain transcripts from the spleen of normal SJL mice. The NPA-PCR method has been specifically designed for the amplification of transcripts
Autor:
B, Melichar, C, Savary, A P, Kudelka, C, Verschraegen, J J, Kavanagh, C L, Edwards, C D, Platsoucas, R S, Freedman
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(3)
The characteristics of antigen-presenting cells in carcinomas that involve the abdominopelvic cavity are unknown. Dendritic cells, a population of antigen-presenting cells, have been identified as lineage-negative human leukocyte antigen (HLA)-DR+ ce
Autor:
J S, Yang, G, Mathioudakis, E, Kruzel, L S, Angelo, L I, Sakkas, J E, Lee, E L, Oleszak, C D, Platsoucas
Publikováno v:
Hematopathology and molecular hematology. 11(1)
The human leukocyte-function-associated antigen-1 (LFA-1) plays a key role in intercellular adhesion interactions of the immune response. A monoclonal antibody (mab), designated LDA-8, is described that recognizes LFA-1. In contrast to nearly all oth
Publikováno v:
Cancer. 78(4)
Melanoma patients who carry the human leukocyte antigen (HLA) Class II allele DQB1*0301 have an increased frequency of metastases at presentation compared with those lacking HLA-DQB1*0301. This study was designed to determine whether HLA-DQB1*0301 is