Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C. D. Kowal"'
Autor:
K Colonello, R Hammond, A J Kunschner, M Baldisseri, Robert P. Edwards, John M. Kirkwood, William E. Gooding, C Paradise, C D Kowal, Barry C. Lembersky, Ronald B. Herberman
Publikováno v:
Journal of Clinical Oncology. 15:3399-3407
PURPOSE To compare the toxicity, pharmacokinetics, and efficacy seen in ovarian cancer patients treated with escalating doses of intraperitoneal (I.P.) interleukin-2 (IL-2) by two different infusion schedules. PATIENTS AND METHODS Forty-five patients
Publikováno v:
European Journal of Cancer. 32:311-315
Stout and colleagues [ Proc Am Assoc Cancer Res 1993, 34, p. 298] previously reported that both hydrocortisone and tamoxifen increased the free fraction of suramin in human plasma. We examined several corticosteroids as well as tamoxifen for their ef
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 48:582-584
Rhythmic myoclonus in an arm began abruptly following an injury and persisted continuously for six years. Topographical EMG showed abnormal activity confined to muscles innervated by the axillary and radial nerves from the posterior cord of the brach
Publikováno v:
Surgery. 104(6)
Elevated levels of carcinoembryonic antigen (CEA) or calcitonin after surgical therapy for medullary carcinoma of the thyroid gland (MCT) indicate the presence of residual or metastatic disease. CEA elevations appear to be prognostically more reliabl
Autor:
C D, Kowal
Publikováno v:
The New England journal of medicine. 290(21)
Autor:
C D, Kowal, J R, Bertino
Publikováno v:
Cancer research. 39(6 Pt 2)
The advantages of hyperthermia for chemotherapy are discussed in detail. These advantages are (a) synergy with chemotherapeutic drugs and also with ionizing radiation, (b) low host toxicity, (c) ease of control (heating precisions in the range of +/-
Publikováno v:
Frontiers of radiation therapy and oncology. 18
Publikováno v:
Cancer research. 41(3)
Mitomycin C and hyperthermia are both toxic to chronically hypoxic EMT6 tumor cells. Combinations of this drug and heat were tested in vitro in normally aerated and chronically hypoxic EMT6 mouse mammary tumor cells to establish whether greater than
Publikováno v:
Seminars in oncology. 10(2 Suppl 2)
5-Fluorouracil (5-FU), when preceded by methotrexate (MTX), results in synergistic tumor cell kill both in vitro and in vivo in mice. Since MTX concentrations 10 microM or greater maximize the synergy in vitro, we administered sequential MTX-5-FU as